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Arquivos de Neuro-Psiquiatria

Print version ISSN 0004-282XOn-line version ISSN 1678-4227

Arq. Neuro-Psiquiatr. vol.78 no.7 São Paulo July 2020  Epub July 01, 2020 


Acute ischemic stroke in a patient with COVID-19

Acidente vascular cerebral isquêmico agudo em paciente com COVID-19

Carla Franco Costa LIMA1

Jorge Luis Bezerra HOLANDA1

Mariana Santos Leite PESSOA1

Pablo Picasso de Araújo COIMBRA1

1Hospital Geral de Fortaleza, Departamento de Radiologia, Fortaleza CE, Brasil.

Coronavirus disease 2019 (COVID-19) seems to be associated with a strong thrombotic tendency, due to different mechanisms still unknown1, which may predispose to arterial and venous thrombosis1,2,3. However, risk estimates for these complications are still preliminary1.

We report a case of an 89-year-old female patient admitted to the emergency room of a tertiary hospital with right hemiparesis, aphasia, and dysarthria. Cranial computed tomography (CT) (Figs. 1,2) and cranial CT angiography (Fig. 3) showed findings suggestive of acute ischemic stroke in the area of the left middle cerebral artery. The patient declared having flu-like symptoms for about two weeks, and chest CT findings were suggestive of viral infection (Fig. 4). The rapid test was performed, and the result was positive for SARS-CoV-2.

Figure 1. Axial image of cranial computed tomography showing an area of cortico-subcortical hypoattenuation with loss of white-gray differentiation in the left insular region (arrow). 

Figure 2. Axial (A) and coronal (B) images of cranial computed tomography compatible with hyperdensity in the left middle cerebral artery (arrows). 

Figure 3. Cranial computed tomography angiography images in 3D volume rendering reconstruction (A) and axial maximum intensity projection reconstruction (B) showing interruption of contrast flow in the M2 segment of the left middle cerebral artery (arrows). 

Figure 4. Axial tomography image of the chest with lung window demonstrating peripheral opacity with ground-glass attenuation in the right lung (arrows). 


1. Klok FA, Kruip MJHA, van der Meer NJM, Arbous MS, Gommers DAMPJ, Kant KM, et al. Incidence of thrombotic complications in critically ill ICU patients with COVID-19. Thromb Res. 2020 Jul;191:145-7. [ Links ]

2. Cui S, Chen S, Li X, Liu S, Wang F. Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia. J Thromb Haemost. 2020 Jun;18(6):1421-4. [ Links ]

3. Bikdeli B, Madhavan MV, Jimenez D, Chuich T, Dreyfus I, Driggin E, et al. COVID-19 and thrombotic or thromboembolic disease: implications for prevention, antithrombotic therapy, and follow-up. J Am Coll Cardiol. 2020 Apr. [Epub ahead of print]. [ Links ]

Revised: May 14, 2020; Received: May 26, 2020; Accepted: May 29, 2020

Correspondence: Mariana Santos Leite Pessoa; E-mail:

Conflict of interest: There is no conflict of interest to declare.

Creative Commons License This is an open-access article distributed under the terms of the Creative Commons Attribution License