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Revista Brasileira de Farmacognosia

Print version ISSN 0102-695X

Rev. bras. farmacogn. vol.2-3-4  São Paulo  1989 



Analgésicos e antipiréticos


Analgesic and antipyretic



Elfriede Marianne Bacchi

Departanento de Farmácia da Faculdade de Ciências Farmacêuticas da Universidade de São Paulo - Caixa Postal 30.786 - São Paulo, SP – Brasil




Revisão sobre os analgésicos e antipiréticos existentes no mercado com os respectivos mecanismos de ação, bem como a perspectiva do uso de plantas medicinais brasileiras.


A short revision about analgesic and antipyretic drugs being used in Brazil and few medicinal plants used by the folk.



Texto completo disponível apenas em PDF.

Full text available only in PDF format.




1 – BASILE, A.C.; SERTIÉ, J.A.A.; FREITAS, P.C.D.; ZANINI, A.C. – Antiinflamatory activity of oleoresin from Brazilian Copaifera. Journal of Ethnopharmacology, 22: 101-9, 1988.         [ Links ]

2 - CORBETT, C.E. –Farmacodinâmica. 6.ed. Rio de Janeiro, Guanabara Koo gan, 1982. 1115p.         [ Links ]

3 - DOHERTY, N.S.; BEAVER, T.U.; CILAN, K.Y.; COUTANT, J.E.; WESTRICH, G.L. The role of prostaglandins in the nociceptive response induced by intraperitoneal injection of zymosan in mice. Br. J. Pharmac, 91: 39-47, 1987.         [ Links ]

4 - DROWER, E.J.; STAPELFELD, A.; MUELLER, R.A.; HAMMOND, D.L. - The anti nociceptive effects of prostaglandin antagonists in the rat. Eu­ropean Journal of Pharmacology, 133:249-56, 1987.         [ Links ]

5 - FLOWER, R.J.; MONCADA, S.; VANE, J.R. - Substâncias antiinflamatórias e analgesicas-antipireticas; drogas empregadas no tratamento da gota. In: As bases farmacológicas da terapêutica.    Eds. Gilman, A. G.; Goodman, L.S.; Rall, T.W.; Murad, F.  7.ed. Rio de Janeiro, Guanabara Koogan, 1987. cap. 29, p.443-69.         [ Links ]

6 - GUYTON, A.C. - Tratado de fisiologia médica. 6.ed. Rio de Janeiro, Interamericana Ltda., 1984. 926p.         [ Links ]

7 - HIDAKA, T.; KAZUNORI, H.; YAMASHITA, T.; WATANABE, K.; HIRAMATSU, Y.; FUJIMURA, H. - Analgesic and anti-inflammatory activities in rats of e-(3,5-di-t-butyl-4-hydroxybenzylidene)--y-butyrolactone(KME-4), and its intestinal damage. J. Phar. Pharmacol., 38:748-53, 1986.         [ Links ]

8 - KAMALI, F.; FRY, J.R.; BELL, G.D. - Salivary secretion of paracetamol in man. J. Pharm. Pharmacol., 39:150-2, 1987.         [ Links ]

9 - LEWIS, W.H. & ELVIN-LEWIS, M.P.F. -Medical botany. New York, John Wiley & Sons, 1977. 515p.         [ Links ]

10 - OPAS, E.E.; HEROLD, E.; DALLOB, A.; LUELL, S.; HUMES, J.L. - Pharmacological modulation of eicosanoid levels and hyperalgesia in yeast -induced inflammation. Biochemical Pharmacology, Great Britain, 36 (4):547-51, 1987.         [ Links ]

11 - RUNORE, M.M. & SCHLICHTING, D.A. -Analgesic effects of antihistaminics. Life Sciences, USA, 36:403-16, 1985.         [ Links ]

12- SERTIE, J.A.A.; BASILE, A.C.; PANIZZA, S.; MATIDA, A.; ZELNIK, R. - Pharmacological assay of Cordia verbenaceae; part 1. Anti-inflammatory activity and toxicity of the crude extract of the leaves. Planta Medica, Stuttgart, 54(1):7-10, 1988.         [ Links ]

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