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Dementia & Neuropsychologia

Print version ISSN 1980-5764

Dement. neuropsychol. vol.7 no.2 São Paulo Apr./June 2013

http://dx.doi.org/10.1590/S1980-57642013DN70200005 

ORIGINAL ARTICLES

Brief cognitive assessment of Alzheimer's disease in advanced stages: Proposal for a Brazilian version of the Short Battery for Severe Impairment (SIB-8)

Avaliação cognitiva breve da doença de Alzheimer em fases avançadas: proposta de uma versão brasileira para bateria de comprometimento grave SIB-8

José Roberto Wajman1 

Paulo Henrique Ferreira Bertolucci1 

1Behavioral Neurology Sector - Neurology and Neurosurgery Department - Federal University of São Paulo - UNIFESP, São Paulo SP, Brazil.

ABSTRACT

The measurement of cognitive abilities of patients with severe dementia can serve a wide range of methodological and clinical needs. Objective: To validate a proposed severe impairment battery SIB-8 for a Brazilian population sample as part of the neuropsychological assessment of patients with Alzheimer's disease (AD) in advanced stages. Methods: After a systematic process of translation and back-translation, the SIB-8 was applied to 95 patients with AD at different stages; moderate, moderately severe and severe according to FAST subdivisions (5, 6 and 7), with scores on the Mini-Mental State Examination (MMSE) of between 5 and 15 and followed by the Division of Behavioral Neurology and the Center for Aging Brain of the Federal University of São Paulo - UNIFESP. Results: Inferential data revealed that the SIB-8 instrument behaved differently at each stage of the disease with a statistical value of sensitivity p<0.001, gradually reflecting the expected course of the dementia, inherent with the decline of cognitive functions. Conclusion: Findings indicated that the SIB-8 is a useful tool for the evaluation and prospective comparison of AD patients in advanced stages, retaining its original characteristics in our population.

Key words: cognitive assessment; severe impairment; dementia; Alzheimer's disease

RESUMO

A quantificação da capacidade cognitiva de pacientes com demência grave pode ser útil para suprir amplas necessidades metodológicas e clínicas. Objetivo: Foi proposta a validação da bateria para comprometimento grave SIB-8 para uma amostra populacional Brasileira como parte integrante da avaliação neuropsicológica de pacientes com doença de Alzheimer (DA) em fases avançada. Métodos: Após sistemático processo de tradução e retrotradução, a SIB-8 foi aplicada em 95 pacientes com DA nas fases moderada, moderadamente grave e grave conforme as subdivisões 5, 6 e 7 da escala FAST, com escore no Mini-Exame do Estado Mental (MEEM) entre 5 e 15 e acompanhados junto ao Setor de Neurologia do Comportamento e do Núcleo de Envelhecimento Cerebral da Universidade Federal de São Paulo - UNIFESP. Resultados: Dados inferenciais revelaram que o instrumento SIB-8 comportou-se de maneira diferente em cada uma das fases da doença com valor estatístico de sensibilidade de p<0,001, relacionando gradualmente o curso esperado da demência, com o inerente declínio das funções cognitivas. Conclusões: Achados indicam a SIB-8 como uma ferramenta útil na avaliação e comparação prospectiva junto a pacientes com DA em fases avançadas, mantendo suas características originais também em nossa população.

Palavras-chave: Avaliação cognitiva; comprometimento grave; demência; doença de Alzheimer

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Received: November 28, 2012; Accepted: February 22, 2013

José Roberto Wajman. Rua Napoleão de Barros, 618 - 04024-001 São Paulo SP - Brazil. E-mail: jrwajman@gmail.com

Disclosure: The authors report no conflicts of interest

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