Abstract Objective The outbreak of the COVID-19 pandemic had a considerable impact on the healthcare access, treatment, and follow-up of oncologic patients. The aim of this study was to evaluate how the COVID-19 pandemic has affected consultation and follow-up demand as well as treatment volume at Brazilian Head and Neck Surgery centers. Methods An anonymous online questionnaire was used for collection of data across all Brazilian Head and Neck Surgery Centers across a 3-month period (April‒June 2021). This information included the characteristics of each center, and the perceived self-reported impact of the COVID-19 pandemic on academic activities, residency training, and the diagnosis, treatment, and follow-up of patients with Head and Neck diseases between 2019 and 2020. Results The response rate across the 40 registered Brazilian Head and Neck Surgery Centers was 47.5% (n = 19). The data showed a significant reduction in the total number of consultations (24.8%) and number of attending patients (20.2%) between 2019 and 2020. The total number of diagnostic exams (31.6%) and surgical procedures (13.0%) conducted over this period also decreased significantly. Conclusions The COVID-19 pandemic had a significant national impact on Brazilian Head and Neck Surgery Centers. Future studies should examine the long-term effects of the pandemic on cancer treatment. Level of evidence Evidence from a single descriptive study.

ABSTRACT This article aims to analyze the relationship between economics and history in the work of Gilberto Freyre, particularly in The Masters and the Slaves and The Mansions and the Shanties. During his studies at Columbia University in the 1920s, the author came into contact with the American New History. Similar to the Annales movement in France, it proposed a new way of thinking History, different from 19th century historiography, which claimed to be scientific in the same sense of any other science. Influenced by Barnes and Seligman, both his professors at Columbia, Gilberto Freyre conceived Brazilian social formation as based on the patriarchy, a category he used as a criterion of periodization. The development and decay of rural patriarchy were analyzed from the viewpoint of its materiality - architectural forms, food diets, clothing, furniture, ecology - making for a very unique vision of Brazilian history, understood by Freyre as an economic interpretation of history.

RESUMO O presente artigo propõe-se a analisar a maneira pela qual se apresentou a relação entre economia e história na obra de Gilberto Freyre, particularmente em Casa-grande & Senzala e Sobrados e Mucambos. Durante sua formação em Columbia nos anos 1920, o autor entrou em contato com o movimento da New History americana que, de maneira similar ao movimento dos Annales na França, propunha uma nova forma de pensar a História. As “novas histórias” forjadas no bojo dos anos 1920 e 1930 buscavam desconstruir alguns pressupostos da Historiografia do século XIX, particularmente a pretensão desta em se equiparar às demais ciências, buscando, a partir dos documentos, reconstituir os fatos tal como “teriam acontecido”. Influenciado por Barnes e Seligman, professores, respectivamente, de História Social e de Economia Política em Columbia, Gilberto Freyre repensou a formação social brasileira a partir da categoria patriarcado, utilizada, pelo autor, não somente como expressão síntese da organização social brasileira, mas também como critério de periodização. A formação do patriarcado rural, durante o período colonial, e sua decadência a partir da chegada da corte em 1808, foram analisadas por Freyre a partir de sua materialidade, reveladas nas formas arquitetônicas, dietas alimentares, vestuário, mobiliário, ecologia. O patriarcado como categoria de periodização e sua dimensão material compuseram, dessa maneira, uma interpretação econômica da história muito singular, que é objeto deste artigo.

RESUMO OBJETIVOS Avaliar a qualidade dos dados antropométricos de crianças registradas no Sistema de Vigilância Alimentar e Nutricional (Sisvan) no período 2008-2017. MÉTODOS Estudo descritivo sobre a qualidade dos dados antropométricos de crianças menores de 5 anos atendidas nos serviços de atenção primária do Sistema Único de Saúde, a partir das bases de dados individuais do Sisvan. A qualidade dos dados foi avaliada anualmente por meio dos indicadores: cobertura, completude, razão entre sexos, distribuição da idade, preferência por dígitos de peso e estatura, valores de escore-z implausíveis, desvio-padrão e normalidade dos escores-z. RESULTADOS No total, 73.745.023 registros e 29.852.480 crianças foram identificados. A cobertura aumentou de 17,7% em 2008 para 45,4% em 2017. A completude da data de nascimento, peso e estatura correspondeu a quase 100% para todos os anos. A razão entre sexos foi equilibrada e aproximadamente similar a razão esperada, variando entre 0,8 e 1. A distribuição da idade revelou maiores percentuais de registros entre as idades de 2 a 4 anos até meados de 2015. Uma preferência pelos dígitos terminais “zero” e “cinco” foi identificada entre os registros de peso e estatura. As porcentagens de escores-z implausíveis excederam 1% para todos os índices antropométricos, com redução dos valores a partir de 2014. Uma alta dispersão dos escores-z, incluindo desvios-padrão entre 1,2 e 1,6, foi identificada principalmente nos índices incluindo estatura e nos registros de crianças menores de 2 anos e residentes das regiões Norte, Nordeste e Centro-Oeste. A distribuição dos escores-z foi simétrica para todos os índices e platicúrtica para estatura/idade e peso/idade. CONCLUSÕES A qualidade dos dados antropométricos do Sisvan para crianças menores de 5 anos melhorou substancialmente entre 2008 e 2017. Alguns indicadores requerem atenção, sobretudo para medidas de estatura, cuja qualidade foi principalmente inferior entre os grupos mais vulneráveis a agravos nutricionais.

ABSTRACT OBJECTIVE To evaluate the quality of anthropometric data of children recorded in the Food and Nutrition Surveillance System (SISVAN) from 2008 to 2017. METHOD Descriptive study on the quality of anthropometric data of children under five years of age admitted in primary care services of the Unified Health System, from the individual databases of SISVAN. Data quality was annually assessed using the indicators: coverage, completeness, sex ratio, age distribution, weight and height digit preference, implausible z-score values, standard deviation, and normality of z-scores. RESULTS In total, 73,745,023 records and 29,852,480 children were identified. Coverage increased from 17.7% in 2008 to 45.4% in 2017. Completeness of birth date, weight, and height corresponded to almost 100% in all years. The sex ratio was balanced and approximately similar to the expected ratio, ranging from 0.8 to 1. The age distribution revealed higher percentages of registrations from the ages of two to four years until mid-2015. A preference for terminal digits “zero” and “five” was identified among weight and height records. The percentages of implausible z-scores exceeded 1% for all anthropometric indices, with values decreasing from 2014 onwards. A high dispersion of z-scores, including standard deviations between 1.2 and 1.6, was identified mainly in the indices including height and in the records of children under two years of age and residents in the North, Northeast, and Midwest regions. The distribution of z-scores was symmetric for all indices and platykurtic for height/age and weight/age. CONCLUSIONS The quality of SISVAN anthropometric data for children under five years of age has improved substantially between 2008 and 2017. Some indicators require attention, particularly for height measurements, whose quality was lower especially among groups more vulnerable to nutritional problems.

ABSTRACT. The study aimed to evaluate performance and growth curves of broilers fed different nutritional relations. A total of 1,440 Cobb-500 male day-old chicks were assigned to eight treatments in a 2 x 2 x 2 factorial arrangement with six replicates of 30 birds each. The main factors were nutritional density (control and high), lysine source (HCl and sulfate), and calcium pidolate (presence and absence). Analyses were made for body weight gain (BWG), and feed conversion rate (FCR) at 21, and 42 days of age. The growth curves were adjusted by weighing a bird per plot every three days. Data for BWG were tested by ANOVA to evaluate the effects of treatments and their interactions at 5% significance, and the Gompertz model was adjusted by NLS. Birds fed a high nutritional density had higher BWG and lower FCR. Calcium pidolate and different sources of lysine did not influence the FCR of broilers, however a triple interaction was evidenced for BWG at 1 to 42 days of age. The day with maximum gain adjusted by Gompertz of all treatments was at the 32nd day of age and the maximum weight (A) was around 5.85 kg.

ABSTRACT Based on data from the author’s ethnographic fieldwork as anthropologist and migration lawyer, the article starts from the writing technique here named “fictional proxy”. It aims to analyze the structure and the conditions of eligibility and veracity required of the biographical narratives that justify the requests for refuge made by international migrants, according to the “Formulário de Solicitação de Reconhecimento da Condição de Refugiado”, the pertinent legal norms and the daily practices that are reiterated in this context, in the city of São Paulo. Hence, it also discusses the different functions performed by Law, politics and emotions in the composition of the true speech and the effects of meaning and power that this production arouses both in the narrator and in their relations with the States of origin and reception.

RESUMO Mobilizando dados do trabalho de campo etnográfico do autor como antropólogo e advogado de migrações, o artigo parte da técnica de escrita aqui nomeada de “procuração ficcional” para analisar a estrutura e as condições de elegibilidade e veracidade exigidas das narrativas biográficas que justificam os pedidos de refúgio dos migrantes internacionais, conforme o “Formulário de Solicitação de Reconhecimento da Condição de Refugiado”, as normas jurídicas pertinentes e as práticas cotidianas que se reiteram nesse contexto, na cidade de São Paulo. São discutidas, então, as diferentes funções exercidas pelo Direito, pela política e pelas emoções na composição do discurso verdadeiro e os efeitos de sentido e de poder que esta produção suscita tanto no narrador quanto em suas relações com os Estados de origem e de acolhida.

ABSTRACT OBJECTIVE To evaluate the quality of anthropometric data of children recorded in the Food and Nutrition Surveillance System (SISVAN) from 2008 to 2017. METHOD Descriptive study on the quality of anthropometric data of children under five years of age admitted in primary care services of the Unified Health System, from the individual databases of SISVAN. Data quality was annually assessed using the indicators: coverage, completeness, sex ratio, age distribution, weight and height digit preference, implausible z-score values, standard deviation, and normality of z-scores. RESULTS In total, 73,745,023 records and 29,852,480 children were identified. Coverage increased from 17.7% in 2008 to 45.4% in 2017. Completeness of birth date, weight, and height corresponded to almost 100% in all years. The sex ratio was balanced and approximately similar to the expected ratio, ranging from 0.8 to 1. The age distribution revealed higher percentages of registrations from the ages of two to four years until mid-2015. A preference for terminal digits “zero” and “five” was identified among weight and height records. The percentages of implausible z-scores exceeded 1% for all anthropometric indices, with values decreasing from 2014 onwards. A high dispersion of z-scores, including standard deviations between 1.2 and 1.6, was identified mainly in the indices including height and in the records of children under two years of age and residents in the North, Northeast, and Midwest regions. The distribution of z-scores was symmetric for all indices and platykurtic for height/age and weight/age. CONCLUSIONS The quality of SISVAN anthropometric data for children under five years of age has improved substantially between 2008 and 2017. Some indicators require attention, particularly for height measurements, whose quality was lower especially among groups more vulnerable to nutritional problems.

RESUMO OBJETIVOS Avaliar a qualidade dos dados antropométricos de crianças registradas no Sistema de Vigilância Alimentar e Nutricional (Sisvan) no período 2008-2017. MÉTODOS Estudo descritivo sobre a qualidade dos dados antropométricos de crianças menores de 5 anos atendidas nos serviços de atenção primária do Sistema Único de Saúde, a partir das bases de dados individuais do Sisvan. A qualidade dos dados foi avaliada anualmente por meio dos indicadores: cobertura, completude, razão entre sexos, distribuição da idade, preferência por dígitos de peso e estatura, valores de escore-z implausíveis, desvio-padrão e normalidade dos escores-z. RESULTADOS No total, 73.745.023 registros e 29.852.480 crianças foram identificados. A cobertura aumentou de 17,7% em 2008 para 45,4% em 2017. A completude da data de nascimento, peso e estatura correspondeu a quase 100% para todos os anos. A razão entre sexos foi equilibrada e aproximadamente similar a razão esperada, variando entre 0,8 e 1. A distribuição da idade revelou maiores percentuais de registros entre as idades de 2 a 4 anos até meados de 2015. Uma preferência pelos dígitos terminais “zero” e “cinco” foi identificada entre os registros de peso e estatura. As porcentagens de escores-z implausíveis excederam 1% para todos os índices antropométricos, com redução dos valores a partir de 2014. Uma alta dispersão dos escores-z, incluindo desvios-padrão entre 1,2 e 1,6, foi identificada principalmente nos índices incluindo estatura e nos registros de crianças menores de 2 anos e residentes das regiões Norte, Nordeste e Centro-Oeste. A distribuição dos escores-z foi simétrica para todos os índices e platicúrtica para estatura/idade e peso/idade. CONCLUSÕES A qualidade dos dados antropométricos do Sisvan para crianças menores de 5 anos melhorou substancialmente entre 2008 e 2017. Alguns indicadores requerem atenção, sobretudo para medidas de estatura, cuja qualidade foi principalmente inferior entre os grupos mais vulneráveis a agravos nutricionais.

Resumo Nanotecnologia é a utilização de materiais na escala nanométrica, em que estes adquirem características próprias. A área de pesquisa e desenvolvimento de novos nanomedicamentos é uma das mais promissoras atualmente, todavia essas partículas necessitam de avaliação particular e ainda não há consenso referente às testagens específicas a serem seguidas, o que dificulta a formação de uma legislação que garanta a segurança e eficácia destes medicamentos, além de um processo de registro mais eficaz. Assim, é necessária uma abordagem bioética da nanotecnologia e sua utilização em medicamentos, visando garantir que o progresso científico não acarrete impactos irreversíveis. Diante dessa problemática, busca-se promover uma discussão nanoética referente ao processo de pesquisa e desenvolvimento de nanomedicamentos, por meio de estudo qualitativo, exploratório-descritivo e de caráter analítico, utilizando revisão bibliográfica, análise documental e dados quantitativos disponíveis como técnicas de pesquisa. nanométrica próprias atualmente seguidas medicamentos eficaz Assim irreversíveis problemática buscase busca se qualitativo exploratóriodescritivo exploratório descritivo analítico bibliográfica

Resumen La nanotecnología utiliza materiales nanométricos, en que estos adquieren características propias. El área de investigación y desarrollo de nuevas nanomedicinas es una de las más prometedoras en la actualidad, sin embargo, estas partículas requieren de una evaluación particular y aún no existe consenso en cuanto a las pruebas específicas que seguir, lo que dificulta establecer una legislación que garantice la seguridad y eficacia de estos medicamentos, además de un proceso de registro más efectivo. Por lo tanto, se necesita un enfoque bioético de la nanotecnología y su uso en medicamentos para garantizar que el avance científico no tenga impactos irreversibles. Ante esta problemática, se pretende promover el debate sobre la nanoética en el proceso de investigación y desarrollo de nanomedicinas a partir de un estudio cualitativo, exploratorio-descriptivo y analítico, que utiliza como técnicas de investigación la revisión bibliográfica, el análisis de documentos y los datos cuantitativos disponibles. nanométricos propias actualidad embargo seguir efectivo tanto irreversibles problemática cualitativo exploratoriodescriptivo exploratorio descriptivo analítico bibliográfica disponibles

Abstract Nanotechnology consist of using materials at the nanoscale, in which they acquire specific characteristics. Nanodrug research and development is one of the most promising fields today; however, these particles require particular evaluation. Moreover, studies lack consensus on which specific tests to follow, thus hindering the elaboration of legislation that ensure their safety and efficacy, as well as a more effective registration process. Thus, a bioethical approach to nanotechnology and its use in drug development is necessary to ensure scientific progress without irreversible impacts. Given this scenario, this article proposes a nanoethics discussion regarding nanodrug research and development by means of a qualitative, exploratory and descriptive analysis, based on literature review, documental analysis and quantitative data available. nanoscale characteristics today however evaluation Moreover follow efficacy process Thus impacts scenario qualitative review available

Resumo Partindo das preocupações disciplinares sobre a obsolescência e a perda de autonomia normativa do Direito Civil, este artigo tem como objetivo estabelecer, a partir de um caso concreto sobre a desapropriação indireta de um terreno urbano ocupado, o conceito de “dogmática ascendente” como alternativa aos procedimentos teóricos que buscam apenas na constitucionalização ou na publicização do Direito Privado os mecanismos de sua atualização. Demonstra-se então a potência que estaria implicada numa retomada, para o Direito Civil, de uma de suas tarefas mais tradicionais: a codificação e a recodificação das relações cotidianas. Civil estabelecer ocupado dogmática ascendente atualização Demonstrase Demonstra se retomada tradicionais cotidianas

Abstract Starting from the disciplinary concerns about the obsolescence and loss of normative autonomy of Civil Law, this article aims to establish, from a concrete case about the indirect expropriation of an occupied urban land, the concept of "ascending dogmatics" as an alternative to theoretical procedures that seek only in the constitutionalization or publicization of Private Law the mechanisms of its updating. It then demonstrates the power that would be implied in a recovery, for Civil Law, of one of its most traditional tasks: the encoding and recoding of everyday relationships. establish land ascending dogmatics updating recovery tasks relationships

Abstract Brazil has an extremely limited railroad network compared to other developed and developing countries. There are projects to expand this mesh. Knowing that the cost of implementing a railroad is high, research for solutions that allow cost reduction is of great importance. But the parameters of the materials used in the subgrade and sub-ballast layers are from other countries, which can cause the cost to increase to meet these parameters. Through strength parameters and mineralogical analysis, it is possible to use or not fine tropical soils as a layer of railway pavement. A critical analysis of the standards that are used to scale and/or verify whether a particular soil can be used in these layers was undertaken. For this, the following tests were performed: Granulometry, Atterberg Limits, Compaction, California Support Index (CBR or ISC), Expansion, MCT Classification Test (Miniature, Compacted, Tropical), Dynamic Triaxial and X-Ray Diffraction. From the results, it could be seen that although one of the soils is thin, it presented satisfactory results in relation to the use in layers of the railway pavement. It was verified that it is necessary to use more modern tests, focusing on mechanistic dimensioning for dimensioning pavement layers.

O artigo parte de uma “cena etnográfica” com migrantes estrangeiros em um escritório de advogado para discutir a função que os documentos migratórios exercem sobre o parentesco no movimento transnacional. Por meio dela, evidencia como o Estado e o Direito disciplinam essas relações e como os próprios migrantes, usando a lógica jurídica da produção documental, elaboram a si mesmos como pessoas, em resistência ao poder estatal. A partir dessa experiência, chamada aqui de parentesco de papel, propõe-se uma reelaboração do conceito de documento, abrangendo tanto a agência burocrática quanto aquela dos sujeitos da documentação.

Paper Kinship: Law, Power and Resistance in an Ethnographic Scene with Foreign Migrants starts from an “ethnographic scene” with foreign migrants in a lawyer’s office to discuss the role that migratory documents play on kinship in the transnational movement. By doing this, it highlights how the state and the Law discipline these relations and how migrants themselves, using the legal logic of documentary production, elaborate themselves as persons, in resistance to state power. Based on this experience, named here as paper kinship, a re-elaboration of the concept of document is proposed, encompassing both the bureaucratic agency and that of the subjects of documentation.

ABSTRACT Given the above, the objective of this study was to evaluate the bromatological, mineral and bioactive compounds of blackberry grown in a subtropical region. Blackberries fruits (Rubus sp.), Grown in an orchard of Unioeste, Campus Marechal Cândido Rondon (Paraná, Brazil), were used. Immediately after harvest, the fruits were taken to the Food Technology Laboratory for chemical analysis and bioactive compounds. The fruit samples for the analysis of reducing, bromatological and mineral sugars were frozen and sent to private laboratories. Hybrids are more perishable than cultivars. There is variation in color among the cultivars and hybrids studied. Hybrids and cultivars of black mulberry have a high content of ascorbic acid and fibers, with emphasis on the cultivar Tupy (75.0 mg 100 mL-1 and 7.23, respectively). Higher pH is verified in the cultivars Tupy and Arapaho (3.22 and 3.24, respectively). The Arapaho cultivar has fewer acid fruits (0.25 g 100 g-1), SS/total acidity ratio (36.88) and reducing sugar content (8.28 g 100g-1). Blackberry fruits are a rich source of bioactive compounds, such as cv. Chickasaw obtaining a higher content of total phenolic compounds (1368.84 mg EAG100mL-1) and the Boysenberry hybrid a greater amount of anthocyanin (5.11mg Ci-3-Gly g -1). The Chickasaw cultivar has a higher lipid content (4.59). There is no difference in moisture content, dry biomass and fruit firmness.

RESUMO: A lagarta-do-cartucho Spodoptera frugiperda Smith, 1797 (Lepidoptera: Noctuidae) é uma praga polífaga que ocasiona danos em diversos cultivos, e o conhecimento do seu espectro de hospedeiros é essencial para o estabelecimento de estratégias de manejo e controle. Assim, o presente estudo registra pela primeira vez a ocorrência de S. frugiperda em videiras brasileiras. Desse modo, recomenda-se a realização de estudos adicionais em laboratório para compreender os aspectos biológicos e os danos as diferentes estruturas (vegetativas e uvas). Essa informação será essencial para avaliar o potencial de dano de S. frugiperda se alimentando de videiras.

ABSTRACT: The fall armyworm, Spodoptera frugiperda Smith, 1797 (Lepidoptera: Noctuidae), is a polyphagous pest that causes losses in several crops. The knowledge of host plants is essential for establishing management and control strategies. The present study reported the first occurrence of S. frugiperda in Brazilian grapevines. It is recommended that further studies should be carried out in the laboratory to understand the biological aspects of the damage to different structures (leaves and grapes). This information will be essential to assess the potential of S. frugiperda damage to vines.

ABSTRACT The Alcantara Launch Center (ALC) is the main Brazilian access to space. It is positioned over a complex terrain, and it has some important buildings for assembling, integration and launching activities, such as the Mobile Integration Tower. Being in a region of prevalent trade winds, the flow interaction between the complex terrain and the buildings can affect the safety of operations on the platform, and the dispersion of toxic gases emitted during the launching. The main objective of this work was to study the influence of topography and buildings on the atmospheric flow of ALC using computational fluid dynamics (CFD) techniques. Three geometries were considered: simplified terrain (case 1), smooth complex terrain (case 2), and roughness complex terrain (case 3). The flow conditions over ALC were simulated using the ANSYS Fluent 19.0 CFD commercial code. The numerical simulations used a realizable ?-? to model turbulence effects and the results presented a good agreement with the in-situ field measurements for the most complex geometry (case 3). The topography clearly influences the flow pattern at ALC, with the cliff influence over the wind being the major cause for establishing the flow patterns.

ABSTRACT. The objective of this study was to evaluate the effect of adding exogenous enzymes to the diet on nutrient intake and digestibility, nitrogen balance, ingestive behavior and rumen movement of ewe lambs. Five ewe lambs, Dorper x Santa Inês crossbred, with an average age of 7 ± 1 months, average weight of 36.40 ± 2.36 kg were assigned in a 5x5 Latin square design. The treatments consisted of adding exogenous enzymes to the concentrate: Allzyme, Fibrozyme®, Amaize®, Mix and Control. Analyses of variance were applied and means were compared by the SNK test, and non-parametric Kruskal Wallis test at 5% significance. The dry matter intake in relation to body weight, crude protein intake and nitrogen intake were higher with the use of amylolytic enzyme compared to the other treatments (p <0.05). Nitrogen balance was higher with the use of amylolytic enzymes and the Allzyme® enzyme complex (p <0.05). A longer time spent in total chewing was observed with the inclusion of fibrolytic and amylolytic enzymes without changes in rumen movement. The use of exogenous enzymes promotes better use of nutrients, with high digestibility of dry matter, neutral detergent fiber and crude protein.