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Diagrama de prevenção de quedas para pessoas idosas: revisão integrativa
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Diniz, Jamylle Lucas

; Sousa, Caroline Ribeiro de

; Aquino, Priscila de Souza

; Silva, Rávida da Rocha Lima

; Evangelista, Brenda Pinheiro

; Coutinho, Janaína Fonseca Victor

; Souza, Rodrigo Lopes de Paula

; Tabosa, Karla Yanca de Sousa

Acta Paulista de Enfermagem

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2024, Volume 37 elocation eAPE02211

Abstract: Es Pt En | Text: Es Pt En | PDF: Es | PDF: Pt | PDF: En

Resumen Objetivo Proponer un diagrama de prevención de caídas para personas mayores, basado en el modelo de promoción de la salud de Nola Pender. Métodos La elaboración del diagrama se basó en el modelo de Nola Pender y sus elementos. Para tal fin, se realizó un estudio de revisión integradora con el objetivo de recopilar datos sobre características y experiencias individuales, sentimientos y conocimientos y adopción de un comportamiento saludable para la prevención de caídas. Después de recopilar la información, se realizó un análisis de similitud de los estudios seleccionados mediante IRaMuTeQ. Los elementos obtenidos del análisis de similitud permitieron agrupar los estudios respecto a los elementos encontrados y, de esta forma, proporcionaron la organización del diagrama de prevención de caídas. Resultados La muestra final estuvo compuesta por 54 artículos, divididos de acuerdo con los elementos del modelo de Nola Pender: 36 abordaban características y experiencias individuales, 40 sentimientos y conocimientos y 20 eran sobre el comportamiento. Los elementos obtenidos del análisis de similitud generaron un conjunto semántico de palabras más frecuentes: caída, prevención, mujer y miedo. Por otro lado, las palabras menos frecuentes fueron: cognición, autoeficacia, transporte y planificación, que contribuyeron para la elaboración del diagrama. Conclusión A partir de la revisión, se elaboró un diagrama que favoreció la identificación de los factores personales, barreras y facilidades para un comportamiento conveniente en la prevención de caídas.

Resumo Objetivo Propor um diagrama de prevenção de quedas para pessoas idosas, baseado no Modelo de Promoção da Saúde de Nola Pender. Métodos A construção do diagrama foi embasada no modelo de Nola Pender e em seus elementos. Para isso, foi realizado um estudo de revisão integrativa, com o objetivo de coletar dados sobre características e experiências individuais, sentimentos e conhecimentos e adoção de comportamento saudável para prevenção de quedas. Após a coleta dessas informações, realizou-se análise de similitude dos estudos selecionados por meio do IRaMuTeQ. Os elementos obtidos da análise de similitude facilitaram o agrupamento dos estudos quanto aos elementos encontrados e, assim, proporcionaram a organização do diagrama de prevenção de quedas. Resultados A amostra final foi constituída de 54 artigos, divididos de acordo com os elementos do modelo de Nola Pender: 36 abordavam características e experiências individuais, 40 sentimentos e conhecimentos, e 20 eram referentes ao comportamento. Os elementos obtidos da análise de similitude geraram um leque semântico de palavras mais frequentes: queda, prevenção, mulher e medo. Já as palavras menos frequentes foram cognição, autoeficácia, transporte e planejamento, os quais contribuíram para a construção do diagrama. Conclusão A partir da revisão, elaborou-se um diagrama, que favoreceu a identificação dos fatores pessoais, barreiras e facilidades, para um comportamento desejável à prevenção de quedas.

Abstract Objective To propose a fall prevention diagram for older adults, based on Nola Pender’s Health Promotion Model. Methods Diagram construction was based on Nola Pender’s model and its elements. For this, an integrative review study was carried out with the objective of collecting data on individual characteristics and experiences, behavior-specific cognitions and affect and behavioral outcome for fall prevention. After collecting this information, a similarity analysis of the selected studies was carried out using IRaMuTeQ. The elements obtained from similarity analysis facilitated the grouping of studies regarding the elements found and thus provided fall prevention diagram organization. Results The final sample consisted of 54 articles, divided according to the elements of Nola Pender’s model: 36 addressed individual characteristics and experiences, 40 referred to behavior-specific cognitions and affect, and 20 referred to behavioral outcome. The elements obtained from the similarity analysis generated a semantic range of the most frequent words: fall, prevention, woman and fear. The least frequent words were cognition, self-efficacy, transportation and planning, which contributed to diagram construction. Conclusion From the review, a diagram was prepared, which favored identifying personal factors, barriers and facilities for a desirable behavior to prevent falls.

https://doi.org/10.37689/acta-ape/2024ar002211

Mineral and Bone Disorder in Patients Living with the Human Immunodeficiency Virus (HIV) on Hemodialysis: a case series
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Vaz, Júlia Braga

; Gueiros, José Edevanilson de Barros

; Coutinho, Luiz Alberto Soares de Araújo

; Russo, Eduarda Cerqueira

; Gueiros, Ana Paula Santana

Portuguese Journal of Nephrology & Hypertension

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dec 2023, Volume 37 N. 4 Pages 201 - 206

Abstract: En | Text: En | PDF: En

ABSTRACT Introduction: Survival of patients living with HIV has increased and low bone mineral density and fractures are reported in this population. Chronic kidney disease causes bone disorder, which also contributes to low bone mineral density, fractures, and vascular calcification. This study aimed to assess the osteometabolic profile in HIV patients undergoing hemodialysis. Methods: Data of 21 patients were assessed. Laboratory: calcium, phosphorus, albumin, intact parathyroid hormone, total alkaline phosphatase, 25OH-vitamin D, CD4 count and HIV viral load. Bone mineral density was assessed by bone densitometry, and x-rays were taken to determine vascular calcification scores. Results: The median age of patients was 48 years (81% male) and the median times of HIV infection and hemodialysis were 132 and 120 months, respectively. Median serum calcium and phosphorus levels were normal and the median intact parathyroid hormone was 360 pg/mL. Osteopenia was diagnosed in 33% of patients and osteoporosis in 33%; 24% of patients had previously suffered fractures. The Kauppila score was higher in patients with fractures (p=0.040). Vascular calcification was identified in 12 (57%) patients. Inverse correlations were demonstrated between the Kauppila score and the T-score of the femoral neck (p<0.001) and the T-score of the lumbar spine (p<0.001); and between the Adragão score and T-score of the femoral neck (p=0.001) and the T-score of the lumbar spine (p=0.001). Conclusion: A high prevalence was observed of low bone mineral density, fractures and vascular calcification in HIV patients on hemodialysis. It is necessary to confirm these results with larger studies and with a control group of non-HIV patients.

https://doi.org/10.32932/pjnh.2023.11.264

Unprepared areas and centralization of oval canals prepared with WaveOne Gold or XP-endo Shaper: microcomputed tomographic analyses
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Marceliano-Alves, Marília FV

; Ronquete, Vivían

; Coutinho, Thais MC

; Boukpessi, Tchilalo

; Salvioni, Amanda LF

; Goulart, Paula ASR

; Limoeiro, Ana GS

; Alves, Flavio RF

; Amoroso-Silva, Pablo A

Acta Odontológica Latinoamericana

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dec 2023, Volume 36 N. 3 Pages 177 - 182

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Current instrumentation systems cannot fully prepare oval root canal systems. This may cause accumulation of hard tissue debris and fail to eliminate bacteria from areas inaccessible to instrumentation, which could perpetuate periapical inflammation and jeopardize the success of endodontic treatment Aim To evaluate the performance of two endodontic systems in oval canals by investigating the changes in volume, unprepared areas, and centering ability of XP-endo Shaper (XPS) and WaveOne Gold (WOG) in oval canals using microcomputed tomography (micro-CT) Materials and Method Thirty mandibular canines were scanned before and after preparation with WOG (25/.07 and 35/.06) or XPS (30/.01) to evaluate the volume, surface area, and canal centralization at 4 mm and 10 mm from the apical foramen Results Volume and surface area increased significantly after preparation with both systems (p<0.05). However, no significant difference was observed in the unprepared areas, regarding either the entire canal (26.21% for WOG and 30.10% for XPS), or the apical segment (18.82% for WOG and 14.63% for XPS) (p >0.05) Conclusions Both systems maintained canal centralization, with no difference between them. XPS and WOG had similar shaping abilities in the mandibular canine, but left almost one third of the unprepared areas.

RESUMO Os sistemas de instrumentação atuais são incapazes de preparar completamente os sistemas de canais radiculares do canal oval, o que pode levar ao acúmulo de detritos de tecido duro e manter micro-organismos em áreas inacessíveis à instrumentação. Essas bactérias poderiam perpetuar a inflamação periapical e comprometer o sucesso do tratamento endodôntico Objetivo Para avaliar o comportamento de dois sistemas endodônticos em canais ovais, esse estudo investigou as alterações no volume, áreas não preparadas e capacidade de centralização do XP-endo Shaper (XPS) e do WaveOne Gold (WOG) em canais ovais usando microtomografia computadorizada (micro-CT) Material e métodos Trinta caninos inferiores foram escaneados antes e depois do preparo com WOG (25/.07 e 35/.06) ou XPS (30/.01) para avaliar o volume, a área de superfície e a centralização do canal a 4 mm e 10 mm do forame apical Resultados O volume e a área de superfície aumentaram significativamente após o preparo com ambos os sistemas (p<0,05). No entanto, não foram observadas diferenças significativas nas áreas não preparadas, não apenas em todo o canal (26,21% para WOG e 30,10% para XPS), mas também no segmento apical (18,82% para WOG e 14,63% para XPS) (p >0,05) Conclusão Ambos os sistemas mantiveram a centralização do canal, sem diferenças entre eles. O XPS e o WOG tiveram habilidades de modelagem semelhantes no canino mandibular, mas deixaram quase um terço das áreas do canal sem preparo.

https://doi.org/10.54589/aol.36/3/177

Physical rehabilitation in Brazilian pediatric intensive care units: a multicenter point prevalence study
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Redivo, Juliana

; Kannan, Harini

; Souza, Andreia Aparecida Freitas

; Colleti Junior, José

; Kudchadkar, Sapna Ravi

; Horigoshi, Nelson Kazunobu

; Costa, Graziela de Araújo

; Castilho, Taísa Roberta Ramos de

; Peron, Paula Peres Domingues

; Scaranto, Walter Perez

; Medeiros, Daniela Nasu Monteiro

; Matsumoto, Toshio

; Almeida, Carlos Gustavo de

; Oliveira, Felipe Rezende Caino de

; Brandão, Marcelo Barciela

; Lima-Setta, Fernanda

; Prata-Barbosa, Arnaldo

; Xavier, Glaciele Nascimento

; Andrade, Livia Barbosa de

; Aguiar, Agda Ultra de

; Coutinho, Marcos Paulo Galdino

; Castro, Roberta Esteves Viera de

; Landy, Glazia André

; Balaniuc, Suzana Lopes Bonfim

; Yamaguchi, Ricardo Silveira

Critical Care Science

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sep 2023, Volume 35 N. 3 Pages 290 - 301

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Objective: To determine the prevalence and factors associated with the physical rehabilitation of critically ill children in Brazilian pediatric intensive care units. Methods: A 2-day, cross-sectional, multicenter point prevalence study comprising 27 pediatric intensive care units (out of 738) was conducted in Brazil in April and June 2019. This Brazilian study was part of a large multinational study called Prevalence of Acute Rehabilitation for Kids in the PICU (PARK-PICU). The primary outcome was the prevalence of mobility provided by physical therapy or occupational therapy. Clinical data on patient mobility, potential mobility safety events, and mobilization barriers were prospectively collected in patients admitted for ≥ 72 hours. Results: Children under the age of 3 years comprised 68% of the patient population. The prevalence of therapist-provided mobility was 74%, or 277 out of the 375 patient-days. Out-of-bed mobility was most positively associated with family presence (adjusted odds ratios 3.31;95%CI 1.70 - 6.43) and most negatively associated with arterial lines (adjusted odds ratios 0.16; 95%CI 0.05 - 0.57). Barriers to mobilization were reported on 27% of patient-days, the most common being lack of physician order (n = 18). Potential safety events occurred in 3% of all mobilization events. Conclusion: Therapist-provided mobility in Brazilian pediatric intensive care units is frequent. Family presence was high and positively associated with out-of-bed mobility. The presence of physiotherapists 24 hours a day in Brazilian pediatric intensive care units may have a substantial impact on the mobilization of critically ill children.

RESUMO Objetivo: Determinar a prevalência e os fatores associados à reabilitação física de crianças em estado grave em unidades de terapia intensiva pediátrica brasileiras. Métodos: Realizou-se um estudo de prevalência pontual multicêntrico, transversal, de 2 dias, abrangendo 27 unidades de terapia intensiva pediátrica (do total de 738) no Brasil em abril e junho de 2019. Este estudo brasileiro fez parte de um grande estudo multinacional chamado Prevalence of Acute Rehabilitation for Kids in the PICU (PARK-PICU). O desfecho primário foi a prevalência de mobilidade proporcionada pela fisioterapia ou pela terapia ocupacional. Foram coletados prospectivamente dados clínicos sobre a mobilidade do paciente, possíveis eventos de segurança de mobilidade e barreiras de mobilização em pacientes admitidos por ≥ 72 horas. Resultados: As crianças com idade inferior a 3 anos eram 68% da população de pacientes. A prevalência de mobilidade fornecida pelo terapeuta foi de 74%, ou 277 dos 375 pacientes-dia. A mobilidade para fora do leito foi mais positivamente associada à presença de familiares (razão de chance ajustada de 3,31; IC95% 1,70 - 6,43) e mais negativamente associada às linhas arteriais (razão de chance ajustada de 0,16; IC95% 0,05 - 0,57). Foram relatadas barreiras à mobilização em 27% dos pacientes-dia, sendo a mais comum a falta de prescrição médica (n = 18). Registaram-se eventuais eventos de segurança em 3% de todos os eventos de mobilização. Conclusão: A mobilidade proporcionada pelo terapeuta nas unidades de terapia intensiva pediátrica brasileiras é frequente. A presença de familiares foi alta e positivamente associada à mobilidade para fora do leito. A presença de fisioterapeutas 24 horas por dia nas unidades de terapia intensiva pediátrica brasileiras pode exercer papel importante na mobilização de crianças em estado grave.

https://doi.org/10.5935/2965-2774.20230388-en

Survival benefit of pediatric-based regimen for adults with acute lymphoblastic leukemia: A single-center retrospective cohort
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Queiroz Neto, Miguel Pedro de

; Costa, Larissa da

; Lisboa, Erica Sabrine Angelo

; Silva, Silvia Nathalia Bueno

; Azambuja, Ana Paula de

; Nunes, Elenaide Coutinho

; Bendlin, Rodrigo Miguel

Hematology, Transfusion and Cell Therapy

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jul 2023, Volume 45 Suppl. 2 Pages S18 - S24

Abstract: En | Text: En | PDF: En

ABSTRACT Introduction: Improving survival of Acute Lymphoblastic Leukemia (ALL) in adult patients has been a challenge. Despite intensive chemotherapy treatment, overall survival is poor. However, several studies demonstrate that young adult patients have better survival when treated with pediatric-based intensive regimens. Considering these results, We decided to treat newly diagnosed ALL patients according to age and risk factors. The goal of this study was to describe the results of this intensive chemotherapy treatment approach for ALL adult patients diagnosed at our institution. Methods: Fifty-eight ALL patients, diagnosed from 2004 to 2013, were included in the analysis. Patients were assigned to either the St. Jude Total Therapy XIIIB high-risk arm (St Jude) or the CALGB 8811 (CALGB). The Kaplan-Meier survival curve was used for the survival analyses and the Cox proportional hazard regression, for multivariable analysis. Results: The overall survival was 22.9% at 10 years. The St. Jude improved survival, compared to the CALGB (p = 0.007), with 32.6% vs. 7.4% survival rate at 10 years. However, no survival benefit was found for patients younger than 20 years old (p = 0.32). The multivariable analysis demonstrated that undetectable minimal residual disease (MRD) and hematopoietic stem cell transplantation (HSCT) had beneficial impact on survival (p = 0.0007 and p = 0.004, respectively). Conclusion: ALL is a disease of poor prognosis for adults. The joint effort to standardize treatment and seek solutions is the way to start improving this scenario.

https://doi.org/10.1016/j.htct.2021.08.016

Prevalence of characteristics associated with sarcopenia in elders: a cross-sectional study
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Sousa, Caroline Ribeiro de

; Coutinho, Janaína Fonseca Victor

; Marques, Marília Braga

; Barbosa, Rachel Gabriel Bastos

; Roriz Filho, Jarbas de Sá

; Soares, Edson Silva

; Nogueira, Charlys Barbosa

; Souza, Rodrigo Lopes de Paula

Revista Brasileira de Enfermagem

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2023, Volume 76 N. 2 elocation e20220209

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

ABSTRACT Objectives: to identify the prevalence and characteristics associated with sarcopenia in elders in Primary Health Care Units. Methods: cross-sectional study with 384 elders. To evaluate sarcopenia, we measured: strength and muscle mass, and physical performance. The elderly were classified as having: probable sarcopenia; sarcopenia; or severe sarcopenia. The chi-squared test and the multinomial logistic regression method were used. Results: the prevalence of probable sarcopenia was 25.52%; of sarcopenia, 11.98%; and of severe sarcopenia, 9.90%. Probable sarcopenia is 1.75 times more prevalent in men; osteoporosis is 2.16 times more prevalent in people with severe sarcopenia; polypharmacy is 1.57 times more likely in individuals with probable sarcopenia; and calf circumference below 31 cm is 2.24 times more likely in patients with sarcopenia and 2.19 times more likely in patients with severe sarcopenia. Conclusions: the highest prevalence was of probable sarcopenia, and the characteristics associated with sarcopenia were sex, osteoporosis, polypharmacy, overweight, obesity, and calf circumference.

RESUMEN Objetivos: identificar prevalencia y características relacionadas a la sarcopenia en personas ancianas de Unidades de Atención Primaria de Salud. Métodos: estudio transversal, con 384 personas ancianas. Para evaluación de sarcopenia, medidos: fuerza y masa muscular, desempeño físico. Clasificadas personas ancianas con: sarcopenia probable; sarcopenia; y sarcopenia grave. Analizado con prueba chi cuadrado y método de regresión logística multinomial. Resultados: la prevalencia de probable sarcopenia fue de 25,52%; sarcopenia, 11,98%; y sarcopenia grave, 9,90%. Hombres son 1,75 vez más prevalentes en individuos con probable sarcopenia; osteoporosis es 2,16 veces más prevalente en la sarcopenia grave; polifarmacia, 1,57 vez más prevalente en la probable sarcopenia; circunferencia de los gemelos menor que 31 cm es 2,24 veces más prevalente en la sarcopenia y 2,19 veces en la sarcopenia grave. Conclusiones: Hubo mayor prevalencia de probable sarcopenia, y las características relacionadas a la sarcopenia fueron: sexo, osteoporosis, polifarmacia, sobrepeso, obesidad y circunferencia de los gemelos.

RESUMO Objetivos: identificar a prevalência e as características associadas à sarcopenia em pessoas idosas de Unidades de Atenção Primária à Saúde. Métodos: estudo transversal, com 384 pessoas idosas. Para avaliação de sarcopenia, mediu-se: força e massa muscular, desempenho físico. Classificaram se pessoas idosas com: sarcopenia provável; sarcopenia; e sarcopenia grave. Analisou-se com teste de qui quadrado e método de regressão logística multinomial. Resultados: a prevalência de provável sarcopenia foi de 25,52%; sarcopenia, 11,98%; e sarcopenia grave, 9,90%. Homens são 1,75 vez mais prevalentes em indivíduos com provável sarcopenia; osteoporose é 2,16 vezes mais prevalente na sarcopenia grave; polifarmácia, 1,57 vez mais prevalente na provável sarcopenia; circunferência da panturrilha menor que 31 cm é 2,24 vezes mais prevalente na sarcopenia e 2,19 vezes na sarcopenia grave. Conclusões: houve maior prevalência de provável sarcopenia, e as características associadas à sarcopenia foram: sexo, osteoporose, polifarmácia, sobrepeso, obesidade e circunferência da panturrilha.

https://doi.org/10.1590/0034-7167-2022-0209

Occult hepatitis B virus infection in patients with chronic liver disease of different etiology in a Brazilian referral center: comparison of two different hepatitis B virus deoxyribonucleic acid amplification protocols: a cross-sectional study
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Faria, Alessandra Coutinho de

; Correa, Bernardo Henrique Mendes

; Faria, Luciana Costa

; Vidigal, Paula Vieira Teixeira

; Xavier, Marcelo Antônio Pascoal

; Ferrari, Teresa Cristina Abreu

Sao Paulo Medical Journal

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2023, Volume 141 N. 3 elocation e2022147

Abstract: En | Text: En | PDF: En

ABSTRACT BACKGROUND: Occult hepatitis B virus infection (OBI) is defined as the presence of hepatitis B virus (HBV) deoxyribonucleic acid (DNA) in the liver of individuals with undetectable hepatitis B virus surface antigen (HBsAg) in the serum. The actual prevalence of OBI and its clinical relevance are not yet fully understood. OBJECTIVE: To evaluate the prevalence of HBV DNA in liver biopsies of HBsAg-negative patients with chronic liver disease of different etiologies in a referral center in Brazil and compare two different HBV DNA amplification protocols to detect HBV. DESIGN AND SETTING: This cross-sectional observational study was conducted at the Liver Outpatient Clinic, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil, between January 2016 and December 2019. METHODS: HBV DNA was investigated in 104 liver biopsy samples from individuals with chronic liver disease of different etiologies, in whom HBsAg was undetectable in serum by nested-polymerase chain reaction (nested-PCR), using two different protocols. RESULTS: OBI, diagnosed by detecting HBV DNA using both protocols, was detected in 6.7% of the 104 individuals investigated. Both protocols showed a good reliability. CONCLUSION: In addition to the differences in the prevalence of HBV infection in different regions, variations in the polymerase chain reaction technique used for HBV DNA amplification may be responsible for the large variations in the prevalence of OBI identified in different studies. There is a need for better standardization of the diagnostic methods used to diagnose this entity.

https://doi.org/10.1590/1516-3180.2022.0147.r1.12072022

Association of Tumor Necrosis Factor-α (-G308A) Polymorphism with risk of Upper Gastrointestinal Bleeding from Schistosomiasis in Pernambuco
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Lima, Bertandrelli Leopoldino de

; Lima, Elker Lene Santos de

; Muniz, Maria Tereza Cartaxo

; Domingues, Ana Lúcia Coutinho

; Silva, Paula Carolina Valença

Revista da Sociedade Brasileira de Medicina Tropical

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2023, Volume 56 elocation e0654-2021

Abstract: En | Text: En | PDF: En

ABSTRACT Background: We evaluated the association between polymorphisms in the tumor necrosis factor alpha (TNF-α) (-G308A) gene and upper gastrointestinal bleeding (UGIB) in schistosomiasis. Methods: This was a transverse study involving 294 Brazilian patients infected with Schistosoma mansoni. Results: The homozygous A/A genotype in TNF-α (-G308A) showed a risk association (prevalence ratio = 1.90, p = 0.008) with UGIB. There was no statistically significant difference in serum TNF-α levels between the clinical groups. Conclusions: The polymorphic TNF-α (-G308A) can be a risk factor for UGIB, in addition to being a potentially predictive factor for the severity of UGIB in schistosomiasis.

https://doi.org/10.1590/0037-8682-0654-2021

Long-term evaluation of patients with BMI = 50kg/m2 who underwent Bariatric Surgery
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MEIRA, MATHEUS DUARTE

; OLIVEIRA, FERNANDO DE SANTA CRUZ

; COUTINHO, LUCAS RIBEIRO

; LEÃO, LUÍS HENRIQUE DE ALBUQUERQUE

; VASCONCELOS, GÉSSICA DE PAULA

; SIQUEIRA, LUCIANA TEIXEIRA DE

; FERRAZ, ÁLVARO ANTÔNIO BANDEIRA

Revista do Colégio Brasileiro de Cirurgiões

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2023, Volume 50 elocation e20233397

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Purpose: to determine the risks and benefits of bariatric surgery in patients with super obesity (SO) in comparison with obesity grades II and III. Methods: retrospective cohort that included a study group of 178 patients with SO and a control group of 181 patients with BMI 35-49.9Kg/m2. The groups were formed in a 1:1 nearest neighbor matching. The main variables were pre- and postoperative BMI and comorbidities, occurrence of severe postoperative complications, bowel obstruction, marginal ulcer, fistulae and 30-day death, besides the necessity of emergency room (ER) admission and abdominal computed tomography (CT) scans in the postoperative period due to acute abdomen. Results: the study group comprised 74.0% of women while the control group had 56.7%. The mean follow-up time was similar between both groups (5.48 x 6.09 years, p=0.216). There was no statistically significant difference on the prevalence of hypertension and T2D between the groups according to the surgical technique. All deaths occurred in the Study group (BMI = 50kg/m2) who underwent RYGB. There was no difference between the groups regarding the occurrence of severe complications. Data on ER admissions and the need for abdominal CT to investigate postoperative abdominal pain did not show statistically significant difference between the groups. Conclusion: despite the high risk related to bariatric surgery in patients with SO, the benefits related to the remission of comorbidities are significant; although being lower than those found in patients with milder grades of obesity.

RESUMO Objetivo: determinar os riscos e benefícios da cirurgia bariátrica em pacientes com superobesidade em comparação com obesidade graus II e III. Métodos: coorte retrospectiva que incluiu um grupo Estudo com 178 pacientes portadores de superobesidade e um controle com 181 pacientes com IMC 35-49.9Kg/m2. Os grupos foram formados numa razão 1:1 com pareamento “vizinho próximo”. As principais variáveis foram comorbidades e IMC pré e pós-operatório, ocorrência de complicações pós-operatórias severas, obstrução intestinal, úlcera marginal, fístula e morte em 30 dias, além da necessidade de idas à emergência e realização de tomografia computadorizada (CT) para investigação de abdome agudo. Resultados: o grupo Estudo foi composto por 74.0% de mulheres, enquanto o Controle teve apenas 56.7%. O tempo médio de seguimento foi similar em ambos os grupos (5.48 x 6.09 anos, p=0.216). Não houve diferença estatisticamente significativa em relação à prevalência de diabetes entre os grupos nem entre a técnica cirúrgica empregada. Todos os óbitos ocorreram no grupo Estudo (IMC = 50kg/m2), com apenas pacientes submetidos ao BGYR. Não houve diferença significativa entre os grupos em relação à ocorrência de complicações pós-operatórias. Ao avaliar idas à emergência e necessidade de TC para investigar dor abdominal, também não foi observada difrença significativa entre os grupos. Conclusão: apesar do alto risco cirúrgico implicado em pacientes portadores de superobesidade, os benefícios relacionados à remissão de comorbidades ainda são significativos; contudo os resultados parecem ser inferiores aos pacientes com graus mais leves de obesidade.

https://doi.org/10.1590/0100-6991e-20233397-en

10.

The impact of post-COVID multicomponent rehabilitation
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Oliveira, Karla Cybele Vieira de

; Ferreira, Ana Paula de Lima

; Silva, Diana de Andrade

; Monteiro, Janaína dos Santos

; Silva, Kennedy Victor

; Lucena, Larissa Coutinho de

; Araújo, Maria das Graças Rodrigues de

Fisioterapia em Movimento

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2023, Volume 36 elocation e36112

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Introduction Post-COVID-19 syndrome is characterized by chronic fatigue and myalgia, among other symptoms, which can limit activities of daily living. Physical therapy protocols with multicomponent exercises combine strength, resistance, balance and gait, producing sig-nificant improvements in functional mobility. Objective Evaluate whether multicomponent rehabilitation is effective in improving functional mobility and quality of life in individuals with post-COVID-19 syndrome. Methods Randomized controlled trial with 59 volunteers, divided into an intervention (IG) and control group (CG), all of whom underwent initial assessment (T0). The IG performed 24 sessions over 12 weeks and the CG did not undergo training. Functional mobility was analyzed using the 6-minute walk test (6MWT) and the Berg balance scale, while the SF-36 questionnaire assessed quality of life. Results In the 6MWT, the IG covered 464.40 + 81.26 meters (T0) and 518.60 + 82.68 meters (T4). The IG Berg scale scores were 48.00 + 4.00 (T0) and 51.90 + 4.26 (T4). In terms of quality of life, the IG obtained mean scores of 96.26 + 10.14 (T0) and 102.60 + 5.53 (T4). None of these measures was statistically significant. Conclusion Individuals who underwent the multicomponent phys-iotherapy protocol showed statistically nonsignificant increases in the variables studied.

Resumo Introdução A síndrome pós-COVID-19 caracteriza-se por fadiga crônica, mialgia, entre outros sintomas que podem causar limitações na realização das atividades de vida diária. Protocolos de fisioterapia com exercício de multicomponentes combinam força, resistência, equi-líbrio e marcha, e produzem melhorias significativas na mobilidade funcional. Objetivo Avaliar se a reabilitação de multicomponentes é eficaz em promover melhora na mobilidade funcional e qualidade de vida em indivíduos com síndrome pós-COVID-19. Métodos Ensaio clínico randomizado, controlado, realizado com 59 voluntários, divididos em grupo intervenção (GI) e grupo controle (GC). Todos fizeram avaliação inicial (T0); GI realizou 24 sessões durante 12 semanas e GC não realizou treinamento. A análise da mobilidade funcional foi realizada através do teste de caminhada de 6 minutos (TC6m) e da escala de equilíbrio de Berg. O questionário SF-36 avaliou a qualidade de vida. Resultados A distância percorrida no TC6m pelo GI foi de 464,40 + 81,26 metros (T0) e de 518,60 + 82,68 metros (T4). A pontuação na escala de Berg do GI foi de 48,00 + 4,00 (T0) e de 51,90 + 4,26 (T4). Na qualidade de vida, GI apresentou escore com média de 96,26 + 10,14 (T0) e 102,60 + 5,53 (T4). Nenhuma destas medidas foram estatisticamente significantes. Conclusão Os indivíduos que foram submetidos ao protocolo fisioterapêutico de multicomponentes apresentaram incrementos nas variáveis estudadas sem significância estatística.

https://doi.org/10.1590/fm.2023.36112

11.

Impact of high-fat diet consumption during prolonged period of pregnancy on placenta structures and umbilical vascular growth in goats
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Bezerra, Alessandra Façanha

; Alves, Juliana Paula Martins

; Fernandes, César Carneiro Linhares

; Cavalcanti, Camila Muniz

; Silva, Maria Raquel Lopes

; Conde, Alfredo José Herrera

; Palomino, Gaby Judith Quispe

; Teixeira, Dárcio Ítalo Alves

; Rego, Aníbal Coutinho do

; Rodrigues, Ana Paula Ribeiro

; Rondina, Davide

Animal Reproduction

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2023, Volume 20 N. 2 elocation e20230019

Abstract: En | Text: En | PDF: En

Abstract This study aimed to verify the impact of high-fat diet consumption for a prolonged period on oxidative stress, fetal growth, umbilical vascular system, and placental structures in pregnant goats. Twenty-two pregnant goats were grouped into the control diet (n= 11) and fat diet (n = 11). Flaxseed meal was added to the fat diet, replacing the corn grain of concentrate, from gestational day 100 to delivery date. Diets were isonitrogenous and isoenergetic, differing in fat content (2.8% vs. 6.3% dry matter). The fat group showed higher feed intake and total plasma lipid levels than the control group (P < 0.001). No difference was found in placentome, and umbilical vascular development. Fat diet-fed goats exhibited a lower systolic peak in the umbilical artery. At delivery, placental traits were similar with the exception of the cotyledon width (P = 0.0075), which was smaller in the fat group and cotyledon surface (P = 0.0047) for multiple pregnancy of fat diet. Cotyledonary epithelium showed more intense staining of lipid droplets and a greater area for lipofuscin staining in the fat group compared to control group (P < 0.001). The mean live weight of the kids was lower in the fat group in the first week after delivery than in control group. Thus, in goats, the continuous administration of a high-fat diet during pregnancy does not appear to modify the fetal-maternal vascular structures but has an impact on a part of the placental structure; therefore, its use must be carefully evaluated.

https://doi.org/10.1590/1984-3143-ar2023-0019

12.

Quality of life and coping in children with cancer
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Matos, Jallana Rios

; Coutinho, Ana Paula Monteiro

; Gonçalves, Ana Luiza Magalhães

; Motta, Alessandra Brunoro

Estudos de Psicologia (Campinas)

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2023, Volume 40 elocation e200210

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Objective: Cancer illness is a stressful event that affects children’s quality of life. This study verified the association between coping and quality of life in 13 children with cancer (6 to 12 years old) from a public hospital in the Southeastern region of the country. Methods: The participants answered the Hospitalization Coping Scale and Pediatric Quality of Life 3.0 (Cancer Module). Descriptive and inferential statistical analyses were applied. A high average of adaptive coping and coping behaviors, such as talking, playing, and taking medicine, were observed. Results: The results suggest a potential positive correlation between quality of life related to the domain nausea, which also showed high scores, and adaptive coping, demonstrating children’s difficulty in dealing with nausea, even after using adaptive coping strategies, and this domain was significant in reducing the quality of life perceived. Conclusion: Understanding coping and qualitywww of life may steer intervention in Pediatric Oncology.

Resumo Objetivo: O adoecimento por câncer é um evento estressor que afeta a qualidade de vida das crianças. Este estudo verificou associações entre coping e qualidade de vida em 13 crianças com câncer (6 a 12 anos), atendidas em um hospital público da região sudeste do país. Método: Os participantes responderam a Escala de Coping da Hospitalização e Pediatric Quality of Life 3.0 (Cancer Module). Análises estatísticas descritivas e inferenciais foram aplicadas. Médias elevadas de coping adaptativo e de comportamentos de coping, como conversar, brincar e tomar remédio, foram verificadas. Resultados: Os resultados sugerem uma possível correlação positiva entre qualidade de vida relacionada ao domínio “enjoo”, que também apresentou escores altos, e coping adaptativo, demonstrando a dificuldade das crianças para lidarem com náuseas, mesmo usando estratégias de coping adaptativo, sendo esse domínio significativo na diminuição da qualidade de vida percebida. Conclusão: Foi concluído que a compreensão do coping e da qualidade de vida pode direcionar a assistência psicológica em Oncologia Pediátrica.

https://doi.org/10.1590/1982-0275202340e200210

13.

Postural Hypervigilance and Perception of Correct Sitting Posture in Individuals With and Without Low Back Pain
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Oliveira, Eduardo Lima de

; Coutinho, Paula Fernanda Ferreira

; Braga, Uiara Martins

; Barsante, Leonardo Drumond

Revista Brasileira de Ortopedia

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nov 2022, Volume 57 N. 6 Pages 947 - 952

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Objectives To verify if there is a difference in postural hypervigilance in sitting in individuals with and without low back pain. Additionally, to observe whether there is a difference in the perception of correct sitting posture between individuals with low back pain and without low back pain. Methods The present study has a cross-sectional observational design, as a sample size of 92 individuals, later divided equally into two groups (with low back pain and without low back pain). Two instruments were used: the hypervigilance scale to analyze the frequency that volunteers correct their sitting posture during the day, and posture scans to investigate the perception of volunteers about the correct sitting posture. The data were submitted to the Shapiro-Wilk Normality test. To compare the values of Hypervigilance Scale, the Mann-Whitney, Chi-Square, and Fisher Exact tests were used to assess correct sitting posture. Results There was no significant difference between postural hypervigilance in sitting between individuals with low back pain and without low back pain. There was no significant difference between the choice of correct sitting posture between the group of individuals with and without low back pain. Conclusion There is no difference between the choice of correct sitting posture and the amount of postural hypervigilance in individuals with or without low back pain.

Resumo Objetivos Verificar se há diferença na hipervigilância postural sentada em indivíduos com e sem dor lombar. Além disso, observar se há diferença na percepção da postura correta sentada entre indivíduos com dor lombar e sem dor lombar. Métodos O presente estudo possui delineamento observacional transversal, como tamanho amostral de 92 indivíduos, posteriormente divididos igualmente em dois grupos (com dor lombar e sem dor lombar). Foram utilizados dois instrumentos: a escala de hipervigilância para analisar a frequência que voluntários corrigem a postura sentada no dia; e o quadro de posturas para investigar a percepção dos voluntários sobre a postura correta sentada. Os dados foram submetidos ao teste de Normalidade de Shapiro-Wilk. Para comparar os valores da Escala de Hipervigilância foi utilizado o teste de Mann-Whitney e o teste Qui-quadrado e exato de Fisher para avaliação da postura correta sentada. Resultados Não houve diferença significativa entre a hipervigilância postural sentada entre indivíduos com dor lombar e sem dor lombar. Não houve diferença significativa entre a escolha da postura correta sentada entre o grupo de indivíduos com e sem dor lombar. Conclusão Não há diferença entre a escolha da postura correta sentada e quantidade de hipervigilância postural em indivíduos com ou sem dor lombar.

https://doi.org/10.1055/s-0042-1756154

14.

Evaluation of 10-minute post-injection 11C-PiB PET and its correlation with 18F-FDG PET in older adults who are cognitively healthy, mildly impaired, or with probable Alzheimer’s disease
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Carneiro, Camila de Godoi

; Faria, Daniele de Paula

; Coutinho, Artur Martins

; Ono, Carla Rachel

; Duran, Fábio Luís de Souza

; da Costa, Naomi Antunes

; Garcez, Alexandre Teles

; da Silveira, Paula Squarzoni

; Forlenza, Orestes Vicente

; Brucki, Sonia Maria Dozzi

; Nitrini, Ricardo

; Busatto Filho, Geraldo

; Buchpiguel, Carlos Alberto

Brazilian Journal of Psychiatry

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oct 2022, Volume 44 N. 5 Pages 495 - 506

Abstract: En | Text: En | PDF: En

Objective: Positron emission tomography (PET) allows in vivo evaluation of molecular targets in neurodegenerative diseases, such as Alzheimer’s disease. Mild cognitive impairment is an intermediate stage between normal cognition and Alzheimer-type dementia. In vivo fibrillar amyloid-beta can be detected in PET using [11C]-labeled Pittsburgh compound B (11C-PiB). In contrast, [18F]fluoro-2-deoxy-d-glucose (18F-FDG) is a neurodegeneration biomarker used to evaluate cerebral glucose metabolism, indicating neuronal injury and synaptic dysfunction. In addition, early cerebral uptake of amyloid-PET tracers can determine regional cerebral blood flow. The present study compared early-phase 11C-PiB and 18F-FDG in older adults without cognitive impairment, amnestic mild cognitive impairment, and clinical diagnosis of probable Alzheimer’s disease. Methods: We selected 90 older adults, clinically classified as healthy controls, with amnestic mild cognitive impairment, or with probable Alzheimer’s disease, who underwent an 18F-FDG PET, early-phase 11C-PiB PET and magnetic resonance imaging. All participants were also classified as amyloid-positive or -negative in late-phase 11C-PiB. The data were analyzed using statistical parametric mapping. Results: We found that the probable Alzheimer’s disease and amnestic mild cognitive impairment group had lower early-phase 11C-PiB uptake in limbic structures than 18F-FDG uptake. The images showed significant interactions between amyloid-beta status (negative or positive). However, early-phase 11C-PiB appears to provide different information from 18F-FDG about neurodegeneration. Conclusions: Our study suggests that early-phase 11C-PiB uptake correlates with 18F-FDG, irrespective of the particular amyloid-beta status. In addition, we observed distinct regional distribution patterns between both biomarkers, reinforcing the need for more robust studies to investigate the real clinical value of early-phase amyloid-PET imaging.

https://doi.org/10.47626/1516-4446-2021-2374

15.

Professor Paula Coutinho (1941-2022)
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Teive, Hélio Afonso Ghizoni

; Coutinho, Léo

; Ferreira, Joaquim José

; Sequeiros, Jorge

Arquivos de Neuro-Psiquiatria

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aug 2022, Volume 80 N. 8 Pages 871 - 874

Abstract: En | Text: En | PDF: En

https://doi.org/10.1055/s-0042-1756170

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