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ABSTRACT This study aimed to determine the antibiotic profile of microorganisms isolated from urine samples of patients with community urine tract infections (UTI) admitted to the University Hospital of the Federal University of Sao Carlos to support an appropriate local empirical treatment. A retrospective cross-sectional study was conducted from October 2018 to October 2020. Data from 1,528 positive urine cultures for bacterial pathogens and antibiograms were tabulated. Bacterial species prevalence and their resistance profile were analyzed and compared by sex and age. For Gram-negative fermenting bacteria, resistance rates were compared between patients with previous hospitalization and the total of infections caused by this group. For comparisons, the Chi-square test was performed, using Fisher’s exact test when necessary (BioEstat program, adopting p ≤ 0.05). A multivariate analysis was applied to assess the effect of the studied variables in predicting multidrug resistance. Infections were more prevalent in women and older adults. Gram-negative bacteria represented 90.44% of total cultures. In both sexes, E. coli prevalence was significantly higher in adults compared with older adults (p < 0.0001). For several antibiotics, resistance rates were higher in the older adults compared with other ages and in patients with Gram-negative fermenting infections and previous hospitalization compared with the total of infections by this group of bacteria. The closer to the hospitalization, the higher the number of antibiotics with superior resistance rates. Resistance rates for aminoglycosides, carbapenems, ceftazidime, nitrofurantoin, piperacillin+tazobactam, and fosfomycin were less than 20%, considered adequate for empirical treatment. Only hospitalization in the previous 90 days was statistically significant in predicting infections by multidrug-resistant bacteria.

https://doi.org/10.1590/s1678-9946202466003

Resistencia antimicrobiana en los principales recursos acuícolas de los departamentos de Tumbes, Piura, San Martin y Puno
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Calizaya, Carla D.

; Reátegui, Erick H.

; Silva, José C.

; Velazco, Rodolfo

; Rodríguez, Liliana

; Angulo, Derly R.

; Llontop, Carlos A.

; Salcedo, Luis A.

; Villena, Carla A.

Uniciencia

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dec 2023, Volume 37 N. 1 Pages 562 - 577

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

Abstract (Objective) The objective of this study was to analyze antimicrobial resistance in Peruvian aquaculture. (Methodology) An observational, descriptive study was carried out. Samples of Argopectenpurpuratus, Oncorhynchus mykiss, Oreochromis niloticus and Litopenaeus vannamei were included. The bacteria Enterococcus spp., Salmonella spp., Erichia coli, Vibrio parahaemolyticus, Aeromonas spp., and Flavobacterium psychrophilum were isolated. Antibiotic resistance was evaluated using antibiograms, and resistant samples were sequenced to identify antimicrobial resistance genes. Absolute and percentage frequencies were calculated. In addition, Wald, Clopper-Pearson, and pooled prevalence confidence intervals were estimated. (Results) In the case of A. purpuratus, 22.2% (95% CI:2.81-60.00) of the E. coli samples were resistant to oxytetracycline. Resistant samples were found in 4.44% (n=2) of the aquaculture production centers (APCs). In O. mykiss, 88.89% (95% CI:51.16-99.72) of the Enterococcus spp. were resistant to osfomycin and oxytetracycline. Resistant samples were found in12.96% of the APCs (n=7). Regarding O. niloticus, 47.31% (95% CI: 37.16-57.46) of the E. coli samples were resistant to oxytetracycline ampicilline>chloramphenicol>fosfomycin and azithromycin. Resistant samples were encountered in 50% of the APCs (n=19). In addition, 89.36% (95% CI:80.55-98.18) of the Enterococcus spp. were resistant to Fosfomycin> chloranphenicol and colistin> oxytetracycline>azithromycin>ampicilline; resistant samples were found in 36.84% of the APCs (n=14). In L. vannamei, 87.11% (95% CI:83.00-91.21) of the Enterococcus spp. samples were resistant to Fosfomycin> colistin> oxytetracycline> azithromycin> ampicilline and resistant samples were found in 100% of the APCs (n=33). Likewise, 35.05% (95% CI:29.74-40.23) of the V. parahaemolyticus samples were resistant to ampicilline>fosfomycin>oxytetracycline>azithromycin>eritromicine>enrofloxacin>ampicilline> chloranfhenicol. Resistant samples were found in 78.79% (n=26) of the APCs (Conclusions) The percentage of APCs with O. niloticus and L. vannamei showed that antimicrobial resistance was high.

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Resumo (Objetivo) O objetivo foi analisar a resistência antimicrobiana na aquicultura peruana. (Metodologia) Foi realizado um estudo observacional, descritivo. Foram incluídas amostras das espécies Argopecten purpuratus, Oncorhynchus mykiss, Oreochromis niloticus e Litopenaeus vannamei. Foram isoladas bactérias dos gêneros Enterococcus spp., Salmonella spp., Aeromonas spp., e espécies de Escherichia coli, Vibrio parahaemolyticus e Flavobacterium psychrophilum. A resistência antimicrobiana foi avaliada por meio de antibiograma, e amostras resistentes foram sequenciadas para identificar genes de resistência antimicrobiana. Foram calculadas as frequências absoluta e percentual, além dos intervalos de confiança de Wald, Clopper-Pearson e as prevalências agrupadas. (Resultados) Em relação a A. purpuratus, 22,2% (IC 95%: 2,81-60,00) das amostras de E. coli foram resistentes à oxitetraciclina. Estes pertenciam a 4,44 % (n=2) dos centros de produção aquícola (CPA). Em O. mykiss, 88,89% (IC 95%: 51,16-99,72) das amostras de rococcus spp. foram resistentes à fosfomicina e oxitetraciclina. Estas pertenciam a 12,96% das CPAs (n=7). Em relação a O. niloticus, 47,31 % IC 95%: 37,16-57,46) das amostras de E. coli foram resistentes à oxitetraciclina>ampicilina>cloranfenicol fosfomicina e azitromicina. Estas pertenciam a 50% das CPAs (n=19). Além disso, 89,36% (IC95%: 80,55-98,18) das amostras de Enterococcus spp. foram resistentes a fosfomicina>cloranfenicol e colistina>oxitetraciclina>azitromicina>ampicilina; estas pertenciam a 36,84% das CPAs (n=14). Em L. vannamei, 87,11% (IC 95%: 83,00-91,21) das amostras de Enterococcus spp foram resistentes à fosfomicina>colistina>oxitetraciclina>azitromicina eritromicina>enrofloxacina> ampicilina>cloranfenicol e pertenciam a 100% das CPAs (n=33). Além disso, 3 ,05% (IC 95%: 29,74-40,23) das amostras de V.parahaemolyticus foram resistentes à ampicilina>fosfomicina>colistina>oxitetraciclina>azitromicina. Estas pertenciam a 78,79% (n=26) das CPAs. (Conclusões) A porcentagem de CPA de O. niloticus L. vannamei, mostrou maior resistência antimicrobiana do estudo.

https://doi.org/10.15359/ru.37-1.30

Glyphosate doses in the suppression of Megathyrsus maximus cv. BRS Quênia intercropped with transgenic maize
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Mello, Carlos E. L.

; Jakelaitis, Adriano

; Silva, Carlos H. de L. e

; Sousa, Gustavo D. de

; Silva, Jaqueline O. da

Revista Brasileira de Engenharia Agrícola e Ambiental

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nov 2023, Volume 27 N. 11 Pages 892 - 899

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT In the intercropping of maize with Megathyrsus maximus, the application of herbicides is a technique that can be used to reduce competition between intercrops. This study aimed to evaluate the effect of different glyphosate doses on suppressing the growth of Megathyrsus maximus cv. BRS Quênia intercropped with maize, as well as in weed control. The randomized block experimental design was used and conducted in the field. The treatments consisted of the application of six glyphosate doses, 0; 48; 96; 240; 480; 960 g acid equivalent [a.e.] ha-1, and a maize treatment without the forage with 960 g acid equivalent [a.e.] ha-1. The dose of 260.87 g a.e. ha-1 provides a 50% response to the forage production variable; therefore, it has the potential to suppress M. maximus cv. BRS Quênia. The presence of forage reduces the density and dry mass of weeds, with the species in the weed community: Ricinus communis, Eleusine indica, Alternanthera tenella, Commelina benghalensis, Conyza sp., and Digitaria horizontalis.

RESUMO No consórcio de milho comMegathyrsus maximus, para reduzir a competição entre as culturas consortes, a aplicação de herbicidas é uma técnica que pode ser utilizada. O objetivo deste estudo foi avaliar o efeito de diferentes doses de glifosato para supressão do crescimento deMegathyrsus maximuscv. BRS Quênia em consórcio com milho, bem como no controle de plantas daninhas. O trabalho foi conduzido a campo, em delineamento experimental de blocos casualizados. Os tratamentos consistiram na aplicação de seis doses de glifosato, 0; 48; 96; 240; 480; 960 g equivalente ácido [e.a.] ha-1 e um tratamento de milho sem a forragem com 960 g equivalente ácido [e.a.] ha-1. A dose de 260,87 g e.a. ha-1 fornece 50% de resposta à variável produção de forragem; portanto, tem potencial para supressão de M. maximuscv. BRS Quênia. A presença da forrageira reduz a densidade e massa seca das plantas daninhas, sendo as principais espécies na comunidade infestante: Ricinus communis, Eleusine indica, Alternanthera tenella, Commelina benghalensis, Conyza sp. e Digitaria horizontalis.

https://doi.org/10.1590/1807-1929/agriambi.v27n11p892-899

Use of glyphosate in the management of Panicum maximum cv. BRS Zuri intercropped with maize
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Silva, Carlos H. de L. e

; Mello, Carlos E. L.

; Silva, Jaqueline O. da

; Jakelaitis, Adriano

; Marques, Renata P.

; Sousa, Gustavo D. de

; Silva, Elias J. da

Revista Brasileira de Engenharia Agrícola e Ambiental

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oct 2023, Volume 27 N. 10 Pages 795 - 802

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT The intercropping between maize and forage species is an alternative commonly used within farming systems. Competition among crops may be a limiting factor in intercropping, compromising maize and forage yield. Although necessary, the literature does not provide satisfactory answers on the interaction of forage crops launched in the market recently, such as BRS Zuri, intercropped with maize. Therefore, techniques such as the use of herbicide subdoses come in as an option to suppress forage growth, making simultaneous cultivation feasible. Thus, the present study aimed to evaluate the effects of glyphosate herbicide subdoses on the development of Panicum maximum cv. BRS Zuri intercropped with Roundup Ready® (RR) maize and how this interaction reflects on the weed population, forage yield, and biometric and yield variables of maize. The experimental design was randomized blocks with treatments consisting of six subdoses of glyphosate herbicide (0, 48, 96, 240, 480, and 960 g acid equivalent [a.e.] ha-1) and maize in monoculture with four replications. For the conditions of this study, the dose of 480 g a.e. ha-1 of glyphosate may be an alternative since there was weed suppression and adequate forage development. Maize yield was not affected by the presence of forage.

RESUMO O consórcio entre milho e espécies forrageiras é uma alternativa comumente utilizada dentro dos sistemas agropecuários. A competição entre as culturas pode ser um fator limitante no consórcio, comprometendo a produção do milho e forragem. Embora necessário, a interação de forrageiras lançadas no mercado nos últimos anos, como a BRS Zuri consorciada com a cultura do milho, não fornece respostas satisfatórias na literatura. Por isso, técnicas como a utilização de subdoses de herbicida entra com uma opção a fim de suprimir o crescimento da forrageira, viabilizando o cultivo simultâneo. Assim, objetivou-se no presente estudo avaliar os efeitos de subdoses do herbicida glyphosate sobre o desenvolvimento de Panicum maximum cv. BRS Zuri consorciado com milho RR (Roundup Ready®) e como essa interação reflete na população de plantas daninhas, no rendimento da forrageira e nas variáveis biométricas e produtivas do milho. O delineamento foi em blocos casualizados, cujos tratamentos consistiram em seis subdoses do herbicida glyphosate (0, 48, 96, 240, 480 e 960 g equivalente ácido [e.a.] ha-1), além do milho em monocultivo com quatro repetições. Para as condições do presente estudo, a dose de 480 g e.a. ha-1 de glyphosate pode ser uma alternativa, visto que houve a supressão de plantas daninhas e um adequado desenvolvimento da forragem. Já o rendimento do milho não foi afetado pela presença da forrageira.

https://doi.org/10.1590/1807-1929/agriambi.v27n10p795-802

Effect of the Temperature and Molar Ratio of Water-Oil on the Enzymatic Hydrolysis Kinetics of the Soybean Oil: Experimental and Mathematical Modeling
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Porcel, Meline G.

; Staudt, Júnior

; Spohr, Gustavo H.

; Silva, Camila da

; Borba, Carlos E.

Journal of the Brazilian Chemical Society

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oct 2023, Volume 34 N. 10 Pages 1486 - 1498

Abstract: En | Text: En | PDF: En

The objective of this paper was to evaluate the kinetics of the hydrolysis of soybean oil by the action of the Lipozyme® TL IM enzyme varying the operational conditions of molar ratio water/oil (9:1-60:1) and temperature (40-64 °C). To describe the experimental data, a mathematical model based on the kinetic mechanism of Ping-Pong Bi Bi (PPBB) was proposed, in which the following steps were not considered formation of the complex enzyme/oil substrate, and formation of the acylated enzyme/oil substrate complex. The results of enzymatic hydrolysis of soybean oil indicated a yield in free fatty acids of 76% at the molar ratio of 46:1 and temperature of 52 °C. Furthermore, based on the values of the determination coefficient and root mean square error, the mathematical model based on the kinetic mechanism of PPBB showed good agreement with the experimental data in a relatively wide temperature range. Thus, it can be a useful tool for the optimization and assessment of the mechanisms of enzymatic hydrolysis of vegetable oil.

https://doi.org/10.21577/0103-5053.20230061

Validation of an Analytical Method by Headspace Gas Chromatography with Flame Ionization and Evaluation of Matrix Effect of Volatile Compounds in Cat Food
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Carvalho, Bruno M.

; Santos, Patrícia D. S. dos

; Silva, Geovane A. R. da

; Senes, Carlos E. R.

; Visentainer, Jesuí V.

; Santos, Oscar O.

Journal of the Brazilian Chemical Society

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aug 2023, Volume 34 N. 8 Pages 1130 - 1138

Abstract: En | Text: En | PDF: En

This study describes the validation of a headspace gas chromatography with flame ionization (HS-GC-FID) method for the determination of propanal, pentanal, hexanal, octanal, and trans-2-nonenal originated by lipid oxidation from cat food samples, as well as the evaluation of the matrix effect in the results. This method was applied to the analysis of commercial cat food and proved to be suitable for the determination of these volatile compounds in different samples. Mean recoveries between 88 and 109% were obtained and repeatability expressed as relative standard deviation was always lower than 6.95%. The intra- and inter-assay precisions ranged from 0.44 to 20.88% and from 0.45 to 20.52%, respectively. In addition, the matrix effect of cat food samples was determined by comparing the slopes of the standard addition method, and the external calibration curve and its influences were verified. These results highlight the high potential of this method, which allows the determination of lipid oxidation products in cat food samples directly, without requiring prior sample preparation techniques.

https://doi.org/10.21577/0103-5053.20230026

Clinical and Urodynamic results of the Argus T® sling in moderate and severe male stress urinary incontinence after radical prostatectomy – a 5 year prospective study.
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Carvalho, Adilson P.

; Silva, André B.

; Lebani, Bruno R.

; Pinto, Eduardo R.

; Felipe, Mariana R.

; Skaf, Milton

; Girotti, Marcia E.

; Zequi, Stenio C.

; Sacomani, Carlos A. R.

; Almeida, Fernando G.

International braz j urol

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aug 2023, Volume 49 N. 4 Pages 452 - 461

Abstract: En | Text: En | PDF: En

ABSTRACT Purpose: Sling as a therapeutic option for male stress urinary incontinence (SUI) has been reviewed in the last two decades, as it is a relatively simpliest surgery compared to artificial urinary sphincter and has the ability to modulate urethral compression. This study aims to evaluate the efficacy, rate of complications, quality of life and the effects on bladder emptying of the Argus T® compressive and ajustable sling in moderate and severe male SUI treatment. Materials and Methods: Men eligible for stress urinary incontinence treatment after radical prostatectomy were recruited and prospectively evaluated, from March 2010 to November 2016. It was selected outpatient men with moderate and severe SUI, after 12 months of radical prostatectomy, who have failed conservative treatment. All patients had a complete clinical and urodynamic pre and post treatment evaluation, by means of clinical history, physical examination, urine culture, 1-hour pad test and ICIq-SF questionnaire. The UDS was performed after 12, 18 and 24 months postoperatively. Results: Thirty-seven men underwent sling surgery, 19 patients (51.4%) with moderate and 18 (48.6%) with severe SUI. The minimum follow-up time was 5 years. Overall, we had a success rate of 56.7% at 60 months follow-up. After surgery, we did not observe significant changes in the urodynamic parameters evaluated during the follow-up. No patient had urodynamic bladder outlet obstruction (BOO) after sling implantation. Readjustment of the Argus T® sling was performed in 16 (41%) of the patients and 51% of the patients reported some adverse event. Conclusion: We demonstrate a long-term efficacy and safety of Sling Argus T® as an alternative to moderate and severe male SUI treatment. Furthermore, in our study bulbar urethra compression does not lead to bladder outlet obstruction.

https://doi.org/10.1590/s1677-5538.ibju.2023.0003

Guía de práctica clínica para el manejo del cáncer de pulmón de células pequeñas: enfermedad extensa
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Cabrera-Miranda, Luis A.

; Díaz-García, Diego A.

; Corona-Cruz, José F.

; Lozano-Ruiz, Francisco J.

; Sánchez-Reyes, Roberto

; Álvarez-Bojórquez, Mario E.

; Blake-Cerda, Mónika

; Rivera-Márquez, Raúl

; López-Saucedo, Raúl A.

; Pérez-Álvarez, Sandra I.

; Bolaño-Guerra, Laura M.

; Alatorre-Alexander, Jorge A.

; Alexander-Meza, Francisco

; Barrón-Barrón, Feliciano

; Blanco-Vázquez, Yazmín C.

; Campos-Gómez, Saúl

; Mata-Moya, Dolores de la

; Figueroa-Martínez, Pedro

; González-Cisneros, Paulina E.

; Íñiguez-García, Marco A.

; Lázaro-León, Jesús M.

; Loyola-García, Ulises

; Morales-Rivera, Marcelino

; Olivares-Torres, Carlos

; Ramos-Ramírez, Maritza

; Sáenz-Frías, Julia A.

; Silva-Bravo, Fernando

; Trejo-Rosales, Rogelio

; Souto-del Bosque, Miguel

; Arrieta, Óscar

Gaceta mexicana de oncología

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jun 2023, Volume 22 N. 2 Pages 55 - 73

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Antecedentes: El cáncer de células pequeñas (CPCP) representa el 13-15% del total de neoplasias primarias de pulmón. Se caracteriza por su rapidez en la tasa de crecimiento y en el desarrollo de metástasis a distancia. Objetivos: Orientar y estandarizar el tratamiento del CPCP enfermedad extensa en México basado en evidencia clínica nacional e internacional. Material y métodos: Este documento se desarrolló como una colaboración del Instituto Nacional de Cancerología y la Sociedad Mexicana de Oncología en cumplimiento con estándares internacionales. Se integró un grupo conformado por oncólogos médicos, cirujanos oncólogos, cirujanos de tórax, radio-oncólogos y metodólogos con experiencia en revisiones sistemáticas de la literatura y guías de práctica clínica. Resultados: Se consensaron, por el método Delphi y en reuniones a distancia, las recomendaciones en CPCP enfermedad extensa, producto de preguntas de trabajo. Se identificó y evaluó la evidencia científica que responde a cada una de dichas preguntas clínicas antes de incorporarla al cuerpo de la guía. Conclusión: Esta guía proporciona recomendaciones clínicas para el manejo de la enfermedad extensa del CPCP y durante el proceso de toma de decisiones de los clínicos involucrados con su manejo en nuestro país para mejorar la calidad de la atención clínica para estos pacientes.

Abstract Background: Small cell lung cancer (SCLC) represents 13-15% of all primary lung neoplasms and is characterized by its rapid growth rate and the rapid development of distant metastases. Objectives: To guide and standardize the treatment of extensive disease small cell lung cancer in Mexico based on national and international clinical evidence. Material and methods: This document was developed as a collaboration between the National Cancer Institute and the Mexican Society of Oncology in compliance with international standards. An interdisciplinary group was formed, including medical oncologists, oncological surgeons, thoracic surgeons, radiation oncologists, and methodologists with experience in systematic reviews of the literature and clinical practice guidelines. Results: A consensus was reached, both by the Delphi method and in remote meetings, of extensive disease recommendations resulting from work questions. The scientific evidence that answers each of these clinical questions was identified and critically evaluated, before being incorporated into the body of evidence of the Guide. Conclusions: This Clinical Practice Guide provides clinical recommendations for the management of extensive disease of SCLC to contribute to the decision-making process of the clinicians involved with its management in our country, hoping that this will contribute to improving the quality of clinical care in these patients.

https://doi.org/10.24875/j.gamo.22000122

Validation of the Compassion Fatigue Short Scale among Portuguese firefighters
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Rodrigues, Fabiana

; Bártolo, Ana

; Sabino, Daniela

; Santos, Isabel M.

; Pereira, Anabela

; Silva, Carlos F.

; Boscarino, Joseph A.

; Adams, Richard E.

Análise Psicológica

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jun 2023, Volume 41 N. 1 Pages 69 - 85

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract This study aimed to adapt the Compassion Fatigue-Short Scale to Portugal and examine the reliability and validity of the Portuguese version of the scale (Pt-CF-Short Scale) among Portuguese firefighters. The factor structure of the Pt-CF-Short Scale was compared to the one-factor model fit and a two-factor model and second-order factor model in a sample of 512 firefighters. Confirmatory factor analysis procedures confirmed the good fit of a second-order factor model with two first-order factors (secondary trauma and job burnout). The Pt-CF-Short Scale showed good internal consistency evidence. The Kessler Psychological Distress Scale (K-10), the Brief Symptom Inventory (BSI) and WHOQOOL-Bref were used as convergent measures to assess psychological distress, anxiety, depression, and interpersonal sensitivity and quality of life, respectively. The measure presented a strong correlation with psychological distress and weak and negative association with quality of life. The Pt-CF-Short Scale contributes to understanding compassion fatigue and its correlates within the context of emergency workers. Results indicate that this scale is a valid and reliable assessment tool in evaluating compassion fatigue.

Resumo Este estudo teve como objetivo adaptar a Compassion Fatigue-Short Scale para Portugal e examinar a fiabilidade e validade da versão portuguesa da escala (Pt-CFShort Scale) entre bombeiros portugueses. A estrutura fatorial da CF-Short Scale foi comparada com o ajuste do modelo de um fator e um modelo de dois fatores e um modelo de fator de segunda ordem em uma amostra de 512 bombeiros. Os procedimentos de análise fatorial confirmatória confirmaram o bom ajuste de um modelo fatorial de segunda ordem com dois fatores de primeira ordem (trauma secundário e esgotamento profissional). As evidências de consistência interna mostraram bons coeficientes e boa validade convergente foi encontrada ao correlacionar essa escala com sofrimento psíquico, ansiedade, depressão e sensibilidade interpessoal. No entanto, essa medida apresentou associação fraca e negativa com as dimensões do WHOQOL-Bref. A validade discriminante foi confirmada. A escala Pt-CF-short contribui para a compreensão da trajetória da fadiga por compaixão e seus correlatos no contexto dos socorristas. Os resultados indicam que esta escala é uma ferramenta de avaliação válida e confiável na avaliação da fadiga por compaixão.

https://doi.org/10.14417/ap.1939

10.

Guía de práctica clínica para el manejo del cáncer de pulmón de células pequeñas: enfermedad limitada
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Cabrera-Miranda, Luis A.

; Lozano-Ruiz, Francisco J.

; Blake-Cerda, Mónika

; Corona-Cruz, José F.

; Sánchez-Reyes, Roberto

; Pérez-Álvarez, Sandra I.

; Díaz-García, Diego A.

; Álvarez-Bojórquez, Mario E.

; Rivera-Márquez, Raúl

; López-Saucedo, Raúl A.

; Bolaño-Guerra, Laura M.

; Maldonado-Magos, Federico

; Aldaco-Sarvide, Fernando

; Alvarado-Zermeño, Adriana

; Barajas-Figueroa, Luis J.

; Bautista-Aragón, Yolanda

; Bolaños-Morales, Francina V.

; Castillo-Ortega, Graciano

; Félix-Leyva, Jesús A.

; Gerson-Cwilich, Raquel

; Guzmán-de Alba, Enrique

; López-Galindo, Ángel A.

; Mariscal-Ramírez, Carlos

; Piñeiro-Retif, Rafael

; Ramos-Prudencio, Rubí

; Rodríguez-Cid, Jerónimo

; Silva-Bravo, Fernando

; Arrieta, Óscar

Gaceta mexicana de oncología

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mar 2023, Volume 22 N. 1 Pages 3 - 23

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Antecedentes: El cáncer de células pequeñas (CPCP) representa el 13-15% del total de neoplasias primarias de pulmón. Se caracteriza por su rapidez en la tasa de crecimiento y en el desarrollo de metástasis a distancia. Objetivos: Orientar y estandarizar el tratamiento del CPCP, enfermedad limitada, en México, basado en evidencia clínica nacional e internacional. Material y métodos: Este documento se desarrolló como una colaboración entre el Instituto Nacional de Cancerología y la Sociedad Mexicana de Oncología en cumplimiento con estándares internacionales. Se integró un grupo conformado por oncólogos médicos, cirujanos oncólogos, cirujanos de tórax, radio-oncólogos y metodólogos con experiencia en revisiones sistemáticas de la literatura y guías de práctica clínica. Resultados: Se consensuaron, por el método Delphi y en reuniones a distancia, las recomendaciones en CPCP enfermedad limitada, producto de las preguntas de trabajo. Se identificó y evaluó críticamente la evidencia científica que responde a cada una de dichas preguntas clínicas, antes de incorporarla a la guía. Conclusión: Esta guía proporciona recomendaciones clínicas para el manejo de la enfermedad limitada del CPCP y durante el proceso de toma de decisiones de los clínicos involucrados con su manejo en nuestro país para mejorar la calidad de la atención clínica en estos pacientes.

Abstract Background: Small cell lung cancer (SCLC) represents 13-15% of all primary lung neoplasms and is characterized by rapid growth rate and development of distant metastases. Objectives: To guide and standardize the treatment of limited disease small cell lung cancer in Mexico based on national and international clinical evidence. Material and methods: This document was developed as a collaboration between the National Cancer Institute and the Mexican Society of Oncology in compliance with international standards. An interdisciplinary group was formed, including medical oncologists, oncological surgeons, thoracic surgeons, radiation oncologists, and methodologists with experience in systematic reviews of the literature and clinical practice guidelines. Results: Consensus recommendations were reached, both by the Delphi method and in remote meetings, for limited SCLC disease resulting from the same number of work questions. The scientific evidence that answers each of these clinical questions was identified and critically evaluated, before being incorporated into the body of evidence of the guide. Conclusion: This guide provides clinical recommendations for the management of limited disease SCLC to contribute to the decision-making process of the clinicians involved with its management in our country, hoping that this will contribute to improving the quality of clinical care in these patients.

https://doi.org/10.24875/j.gamo.22000121

11.

Features Extraction for Classification in Switching Devices using Fiber Bragg Grating
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Benetti, Daniel

; Dureck, Eduardo H.

; Dreyer, Uilian J.

; Lazzaretti, André E.

; Pipa, Daniel R.

; Silva, Jean Carlos Cardozo da

Journal of Microwaves, Optoelectronics and Electromagnetic Applications

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mar 2023, Volume 22 N. 1 Pages 149 - 161

Abstract: En | Text: En | PDF: En

Abstract Vibration analysis systems are used to assess the operational condition of machines and electromechanical components in various applications. This work presents a measurement and feature extraction system that analyzes dynamic strain patterns in signals measured by fiber Bragg grating (FBG). The features were used to identify different simulated operational conditions in an electromechanical relay. The selection of the best feature space in the first approach was performed by statistical criteria that determine the threshold values and frequency bands to calculate each signal's switching time and power spectral density (PSD). These parameters are used in the support vector machine (SVM) algorithm, which presents 98 % accuracy for distinguishing four distinct conditions. Another methodology for extracting features, called wavelet scattering transform (WST), was used to demonstrate that it is possible to achieve even better performance levels. The results allow extending the methodology to more complex systems.

https://doi.org/10.1590/2179-10742023v22i1270775

12.

Parasitism of Automeris liberia (Lepidoptera: Saturniidae) by tachinids (Diptera: Tachinidae) in oil palm in the Brazilian Amazon Lepidoptera (Lepidoptera Saturniidae Diptera (Diptera Tachinidae
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SILVA, Kelly Barbosa da

; SILVA, Chryslane Barbosa da

; GOULART, Henrique Fonseca

; TINÔCO, Ricardo Salles

; SOUZA, Jose Malta de

; CHIA, Gilson Sanchez

; GARCIA, Carlos Henrique

; TOMA, Ronaldo

; GUZZO, Elio Cesar

Acta Amazonica

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mar 2023, Volume 53 N. 1 Pages 20 - 23

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Lagartas de Automeris liberia (Lepidoptera: Saturniidae) são importantes desfolhadoras da palma de óleo, Elaeis guineensis (Arecaceae) nas Américas Central e do Sul. A família Tachinidae (Diptera) compreende moscas parasitoides de muitos insetos-praga, principalmente da ordem Lepidoptera. Contudo, o registro de hospedeiros de taquinídeos ainda é relativamente escasso. No presente trabalho, relatamos a ocorrência de Belvosia sp. aff. williamsi (Diptera: Tachinidae: Exoristinae: Goniini) e Leptostylum oligothrix (Diptera: Tachinidae: Exoristinae: Blondeliini) parasitando lagartas de A. liberia em E. guineensis no município de Tailândia, Pará, Brasil. Trata-se do primeiro registro do parasitismo de A. liberia por Leptostylum no Brasil, bem como o primeiro por Belvosia no mundo. Lepidoptera (Lepidoptera Saturniidae óleo Arecaceae (Arecaceae Sul Diptera (Diptera insetospraga, insetospraga insetos praga, praga insetos-praga Contudo escasso trabalho sp aff Exoristinae Goniini Blondeliini E Tailândia Pará Brasil Tratase Trata se mundo

ABSTRACT Automeris liberia (Lepidoptera: Saturniidae) caterpillars are important defoliators of the African oil palm, Elaeis guineensis (Arecaceae) in Central and South America. The family Tachinidae (Diptera) comprises flies that are parasitoids of many insect pests, mainly from the order Lepidoptera. However, host records for tachinids are still relatively scarce. In the present work, we report the occurrence of Belvosia sp. aff. williamsi (Diptera: Tachinidae: Exoristinae: Goniini) and Leptostylum oligothrix (Diptera: Tachinidae: Exoristinae: Blondeliini) parasitizing caterpillars of A. liberia in E. guineensis in the municipality of Tailândia, state of Pará, Brazil. This is the first record of the parasitism of A. liberia by Leptostylum in Brazil, as well as by Belvosia in the world. Lepidoptera (Lepidoptera Saturniidae palm Arecaceae (Arecaceae America Diptera (Diptera pests However scarce work sp aff Exoristinae Goniini Blondeliini A E Tailândia Pará Brazil world

https://doi.org/10.1590/1809-4392202201361

13.

Profitability of using irrigation in forage cactus-sorghum intercropping for farmers in semi-arid environment
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Silva, Thieres G. F. da

; Jardim, Alexandre M. da R. F.

; Diniz, Wellington J. da S.

; Souza, Luciana S. B. de

; Araújo Júnior, George do N.

; Silva, Gabriel Í. N. da

; Alves, Cleber P.

; Souza, Carlos A. A. de

; Morais, José E. F. de

Revista Brasileira de Engenharia Agrícola e Ambiental

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feb 2023, Volume 27 N. 2 Pages 132 - 139

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O uso da irrigação desempenha papel fundamental no avanço das fronteiras agrícolas e no aumento da produtividade nas áreas de cultivo, principalmente em ambientes semiáridos que apresentam alta variação espaço-temporal de chuvas. Essa prática é sugerida até mesmo para cultivos adaptados como palma forrageira (Opuntia sp.) e sorgo (Sorghum bicolor). Assim, objetivou-se avaliar a rentabilidade do uso da irrigação no sistema solteiro e sistema consorciado palma-sorgo no semiárido. O delineamento experimental foi em blocos casualizados em esquema fatorial 5 × 3: cinco lâminas de irrigação por gotejamento (0, 25, 50, 75 e 100% da evapotranspiração de referência - ET0) e três sistemas de cultivo (palma forrageira solteira, sorgo solteiro e consórcio palma-sorgo), com quatro repetições. O tratamento 0% ET0 correspondeu à condição de sequeiro com uma lâmina de 355 mm. Foi conduzido um ciclo de palma e dois de sorgo (planta e rebrota) compreendidos de novembro 2014 a novembro de 2015. Verificou-se que os maiores custos para implantação dos sistemas de cultivo em condições irrigadas se devem à aquisição do sistema de irrigação e insumos, representando 85,3% do custo operacional efetivo. O sistema sorgo solteiro e o sistema palma forrageira-sorgo proporcionaram as maiores produtividades de matéria fresca (62.013,05 e 60.075,36 kg ha-1), respectivamente. Com base em indicadores econômicos, a adoção de lâminas de irrigação (25, 50, 75 e 100% ET0) promoveu lucros para os sistemas (solteiro e consorciado) a partir do segundo ano de implantação.

ABSTRACT Irrigation plays a fundamental role in advancing agricultural frontiers and increasing crop productivity, especially in semi-arid environments, because they exhibit high spatiotemporal rainfall variation. This practice is suggested even for adapted crops, such as forage cactus (Opuntia sp.), sorghum (Sorghum bicolor), and single or intercropping systems. In this study, aimed to evaluate the profitability of using irrigation in a single and intercropping forage cactus-sorghum system in a semi-arid region. The experimental design was in randomized blocks in a 5 × 3 factorial arrangement: five drip irrigation depths (0, 25, 50, 75, and 100% of the reference evapotranspiration - ET0) and three cropping systems (single forage cactus, single sorghum, and intercropping forage cactus-sorghum), with four replicates. The 0% ET0 treatment corresponded to rainfed conditions at a depth of 355 mm. A cycle of forage cactus and two sorghum cultivars (plant and regrowth) was conducted between November 2014 and November 2015. It was verified that the highest costs for implantation of the crop systems in irrigated conditions are due to the acquisition of irrigation and input systems, representing 85.3% of the effective operational cost. The single sorghum and forage cactus-sorghum systems provided the highest fresh matter productivity (62,013.05 and 60,075.36 kg ha-1, respectively). Based on economic indicators, the adoption of irrigation depths (25, 50, 75, and 100% ET0) promoted profits for the systems (single and intercropping) from the second year of implementation.

https://doi.org/10.1590/1807-1929/agriambi.v27n2p132-139

14.

Salinity-tolerant dwarf cashew rootstock has better ionic homeostasis and morphophysiological performance of seedlings
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Sousa, Valéria F. de O.

; Santos, Gisele L. dos

; Maia, Josemir M.

; Maia Júnior, Sebastião de O.

; Santos, João P. de O.

; Costa, José E.

; Silva, Anselmo F. da

; Dias, Thiago J.

; Ferreira-Silva, Sérgio L.

; Taniguchi, Carlos A. K.

Revista Brasileira de Engenharia Agrícola e Ambiental

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feb 2023, Volume 27 N. 2 Pages 92 - 100

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Considerando a relevância do cajueiro e a limitação imposta pelo estresse salino em regiões semiáridas, o uso de alternativas capazes de mitigar os efeitos deletérios em decorrência da salinidade são de grande importância ao setor produtivo. O uso de plantas enxertadas, principalmente com porta-enxertos de materiais tolerantes, influencia no acúmulo de íons tóxicos nas folhas das mudas enxertadas. Assim, o objetivo deste trabalho foi avaliar características morfofisiológicas e concentração foliar de Na+, K+, Ca+2 de combinações de copa e porta-enxerto de cajueiro anão precoce, contrastantes à salinidade. O experimento foi realizado em delineamento inteiramente casualizado, com cinco repetições, tendo os tratamentos dispostos em arranjo fatorial de 4 × 3, correspondentes a quatro combinações de mudas enxertadas (auto-enxerto CCP 09/CCP 09, CCP 09/CCP 76, auto-enxerto CCP 76/CCP 76 e CCP 76/CCP 09) e a três concentrações de NaCl (0-controle, 50 e 100 mM L-1). Foram avaliados altura, número de folhas, área foliar, massa seca, índice de tolerância e concentração foliar de Na+, K+ e Ca+2 após 30 dias da aplicação das concentrações de NaCl. A combinação copa/porta-enxerto CCP 76/09 apresentou tolerância à salinidade de 50 mM L-1, devido ao aumento da área foliar e número de folhas. A combinação copa/porta-enxerto CCP 76/09 foi mais adequada, pois manteve a concentração foliar de K+ e o menor concentração de Na+.

ABSTRACT Considering the cashew tree’s relevance and the limitations imposed by salinity stress in semi-arid regions, the use of alternatives capable of mitigating the harmful effects due to salinity is of great importance to the production sector. The use of grafted plants, especially with rootstock made of tolerant materials, influences the accumulation of toxic ions in leaves of grafted seedlings. Thus, the objective of this work was to evaluate morphophysiological characteristics and leaf concentrations of Na+, K+ and Ca+2 of combinations of scion and rootstock of early dwarf cashew, contrasting in terms of salinity tolerance. The experiment was carried out in a completely randomized design with five replicates, in a 4 × 3 factorial arrangement, corresponding to four dwarf cashew scion/rootstock combinations (self-graft CCP 09, CCP 09/CCP 76, self-graft CCP 76, and CCP 76/CCP 09) and three NaCl concentrations (0, 50, and 100 mM L-1). Height, number of leaves, leaf area, dry matter, tolerance index and leaf concentrations of Na+, K+ and Ca+2 were evaluated after 30 days of application of NaCl concentrations. The scion/rootstock combination CCP 76/09 showed tolerance to 50 mM L-1, due to the increase of leaf area and number of leaves. The scion/rootstock combination CCP 76/09 was more suitable, as it kept the leaf K+ concentration and had the lowest Na+ concentration.

https://doi.org/10.1590/1807-1929/agriambi.v27n2p92-100

15.

Judicialização do direito à saúde com foco em doenças tropicais negligenciadas: dimensões e desafios no Estado do Piauí, Nordeste do Brasil, 2000-2020
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Andrade, Nayla Rochele Nogueira de

; Nunes, Carlos Francisco Oliveira

; Ferreira, Anderson Fuentes

; Araújo, Carmem E. Leitão

; Albuquerque, Felipe Braga

; Silva, José Alexandre Menezes da

; Araújo Filho, Francisco José de

; Freire, Patrícia de Sá

; Ramos Jr., Alberto Novaes

Ciência & Saúde Coletiva

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jan 2023, Volume 28 N. 1 Pages 7 - 22

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O objetivo deste artigo é analisar a magnitude e o perfil das demandas judiciais por bens e serviços de saúde pública, verificando também a presença de demandas judiciais para doenças tropicais negligenciadas (DTNs) no Estado do Piauí entre 2000-2020. Estudo transversal descritivo a partir de bases de dados do Tribunal de Justiça do Piauí acerca de processos judiciais demandando bens e serviços de saúde à administração pública direta. Foram identificados inicialmente um total de 6.658 processos judiciais. Após análise de elegibilidade, 1.384 processos (20,8%) foram analisados, verificando-se aumento da demanda a partir de 2017. Ressalta-se as características: origem na capital Teresina (614; 44,4%), 40 a 59 anos de idade (372; 26,9%), sexo feminino (761; 55,0%), agricultores (123; 8,9%), assistência jurídica pública (1.063; 76,8%), julgados procedentes (594; 42,9%). Cinco (5; 0,4%) demandas judiciais para DTNs, uma leishmaniose visceral solicitando transporte, procedente; quatro para hanseníase (dois medicamentos, um concedido, outro extinto sem resolução do mérito, uma consulta e um exame, ambos concedidos). A judicialização do direito à saúde é expressiva e crescente no estado do Piauí. A baixa demanda relacionada a DTNs pode traduzir limitação de acesso não apenas à saúde, mas ao Poder Judiciário.

Abstract This article aims to analyse the magnitude and profile of legal demands for public health goods and services, also verifying the presence of legal demands for neglected tropical diseases (NTDs) in the State of Piauí between 2000-2020. Cross-sectional descriptive study based on the databases of the Court of Justice of Piauí on lawsuits demanding from the Direct Public Administration, goods and health services. A total of 6,658 lawsuits were initially identified. After eligibility analysis, 1,384 cases (20.8%) were analysed, with an increase in demand from 2017. We highlight the characteristics: origin in the capital Teresina (614; 44.4%), 40 to 59 years of age (372; 26.9%), female (761; 55.0%), farmers (123; 8.9%), public legal assistance (1,063; 76.8%), upheld (594; 42.9%). Five (5; 0.4%) lawsuits for NTDs, one visceral leishmaniasis requesting transportation, with granting, four for leprosy (two medicines, one granted, other extinguished without resolution of the merit, one consultation and one exam granted). The judicialization of the right to health is expressive and growing in the State of Piauí. The low demand related to NTDs may translate into limited access not only to health care, but also to the judiciary.

https://doi.org/10.1590/1413-81232023281.06402022

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