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au:SILVA, RONALDO JOSE DA

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Evaluation of the use of a Renal Health application by kidney transplant recipients
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Oliveira, Juliana Gomes Ramalho de

; Sanders-Pinheiro, Hélady

; Freitas Filho, Ronaldo Almeida de

; Vasconcelos Filho, José Eurico

; Askari, Marjan

; Silva Júnior, Geraldo Bezerra da

Revista Latino-Americana de Enfermagem

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dec 2023, Volume 31 elocation e3822

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

Abstract Objective: to evaluate the use of a renal health application by kidney transplant recipients. Method: a retrospective, observational study with a sample composed of individuals registered in the kidney transplant section of the application from July of 2018 to April of 2021. Demographic data, data entry, time of use, weight, blood pressure, blood glucose, creatinine, medication schedules, appointments, and tests were the variables collected. Descriptive analysis of the data was performed. Results: eight hundred and twenty-three downloads of the application were identified, and 12.3% of those were registered as kidney transplant recipients, the majority from southeastern Brazil (44.9%), 36±11 years old, and female (59.1%). Of the sample, 35.1% entered information such as creatinine (62%), weight (58.2%), and blood pressure (51.8%). Most used the application for one day (63.3%) and 13.9% for more than one hundred days. Those who used it for more than one day (36.7%) recorded weight (69%), medication intake (65.5%) and creatinine (62%), and scheduled appointments (69%). Conclusion: the kidney transplant recipient section of the Renal Health application generated interest in the young population, but showed low adherence throughout the assessed months. These results offer a relevant perspective on the implementation of mHealth technologies in kidney transplantation.

Resumen Objetivo: evaluar el uso de la aplicación Renal Health por parte de los receptores de trasplante renal. Método: estudio observacional retrospectivo con una muestra compuesta por usuarios que se registraron en la sección de trasplantados renales dentro de la aplicación desde julio de 2018 hasta abril de 2021. Se recolectaron las siguientes variables: datos demográficos, ingreso de datos, tiempo de uso, registros de peso, presión arterial, glucosa en sangre, creatinina, esquemas de medicación, consultas y exámenes. Se realizó un análisis descriptivo de los datos. Resultados: Ocurrieron 1.823 descargas de la aplicación y 12,3% se registró en la sección de trasplantados, la mayoría del sudeste de Brasil (44,9%), con edad de 36±11 años y del sexo femenino (59,1%). De la muestra, 35,1% ingresó información como: creatinina (62%), peso (58,2%) y presión arterial (51,8%). La mayoría utilizó la aplicación durante un día (63,3%) y el 13,9% más de cien días. Quienes lo usaron por más de un día (36,7%), agregaron peso (69%), programación de consultas (69%), medicación (65,5%) y creatinina (62%). Conclusión: la sección para trasplantados renales de la aplicación Renal Health despertó interés en la población joven, pero mostró baja adherencia en los meses evaluados. Estos resultados ofrecen una perspectiva relevante en la implementación de tecnologías mHealth en el trasplante renal.

Resumo Objetivo: avaliar o uso do aplicativo Renal Health por transplantados renais. Método: estudo observacional retrospectivo com amostra composta por usuários que realizaram cadastro na seção para transplantados renais do aplicativo de julho de 2018 a abril de 2021. Foram coletadas as seguintes variáveis: dados demográficos, inserção de dados, tempo de uso, registros de peso, pressão arterial, glicemia, creatinina, horários das medicações, consultas e exames. Realizou-se análise descritiva dos dados. Resultados: houve 1.823 downloads do aplicativo e 12,3% cadastraram-se na seção para transplantados renais, a maioria do Sudeste do Brasil (44,9%), com 36±11 anos e do sexo feminino (59,1%). Da amostra, 35,1% inseriram informações como creatinina (62%), peso (58,2%) e pressão arterial (51,8%). A maioria utilizou o aplicativo por um dia (63,3%) e 13,9% por mais de cem dias. Os que utilizaram por mais de um dia (36,7%), inseriram peso (69%), agendaram consultas (69%), medicações (65,5%) e creatinina (62%). Conclusão: a seção para transplantados renais do aplicativo Renal Health despertou interesse na população jovem, mas apresentou baixa adesão ao longo dos meses avaliados. Esses resultados oferecem perspectiva relevante na implementação de tecnologias mHealth no transplante renal.

https://doi.org/10.1590/1518-8345.6039.3822

Sexually Transmitted Infections Lesions Found during Colonoscopies
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Gomes, Alexandre

; Sampaio Netto, João Batista

; Ayres, Ricardo de Oliveira

; Rodrigues, José Mauro da Silva

; Borghesi, Ronaldo Antonio

Journal of Coloproctology (Rio de Janeiro)

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jun 2023, Volume 43 N. 2 Pages 75 - 81

Abstract: En | Text: En | PDF: En

Abstract Introduction Anal examination and videoanoscopy (VA) are rarely performed during colonoscopies. In recent years, there has been a considerable increase in lesions of sexually transmitted anal and rectal infections, but these conditions are not noticed or reported during routine colonoscopy. Objective To raise awareness regarding the fortuitous findings of lesions and sexually transmitted infections (STIs) in colonoscopy exams and to demonstrate that anal examination and VA provide important information and should be routinely performed. Methods We conducted a descriptive retrospective study in 16,132 patients screened by colonoscopy and VA between 2006 and 2018. Among numerous other findings, the presence of anal condylomata and sexually transmitted retitis or perianal dermatitis was observed. The rates of each finding were calculated, and the patients were subdivided by sex and into age groups by blocks of ten years. Results Among the 16,132 colonoscopies performed, 26 cases of condyloma (0.16%) and 50 cases of proctitis or perianal dermatitis suspicious for STI (0.33%) were found. Conclusion Performing anal examination and VA systematically in all routine colonoscopies enabled the identification of numerous anal conditions, including several fortuitous cases of STIs. The study proposes that anal examination and VA should be performed in all routine colonoscopies and, in suspected cases, complementary tests for STIs.

https://doi.org/10.1055/s-0043-1769486

Parasitism of Automeris liberia (Lepidoptera: Saturniidae) by tachinids (Diptera: Tachinidae) in oil palm in the Brazilian Amazon Lepidoptera (Lepidoptera Saturniidae Diptera (Diptera Tachinidae
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SILVA, Kelly Barbosa da

; SILVA, Chryslane Barbosa da

; GOULART, Henrique Fonseca

; TINÔCO, Ricardo Salles

; SOUZA, Jose Malta de

; CHIA, Gilson Sanchez

; GARCIA, Carlos Henrique

; TOMA, Ronaldo

; GUZZO, Elio Cesar

Acta Amazonica

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mar 2023, Volume 53 N. 1 Pages 20 - 23

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Lagartas de Automeris liberia (Lepidoptera: Saturniidae) são importantes desfolhadoras da palma de óleo, Elaeis guineensis (Arecaceae) nas Américas Central e do Sul. A família Tachinidae (Diptera) compreende moscas parasitoides de muitos insetos-praga, principalmente da ordem Lepidoptera. Contudo, o registro de hospedeiros de taquinídeos ainda é relativamente escasso. No presente trabalho, relatamos a ocorrência de Belvosia sp. aff. williamsi (Diptera: Tachinidae: Exoristinae: Goniini) e Leptostylum oligothrix (Diptera: Tachinidae: Exoristinae: Blondeliini) parasitando lagartas de A. liberia em E. guineensis no município de Tailândia, Pará, Brasil. Trata-se do primeiro registro do parasitismo de A. liberia por Leptostylum no Brasil, bem como o primeiro por Belvosia no mundo. Lepidoptera (Lepidoptera Saturniidae óleo Arecaceae (Arecaceae Sul Diptera (Diptera insetospraga, insetospraga insetos praga, praga insetos-praga Contudo escasso trabalho sp aff Exoristinae Goniini Blondeliini E Tailândia Pará Brasil Tratase Trata se mundo

ABSTRACT Automeris liberia (Lepidoptera: Saturniidae) caterpillars are important defoliators of the African oil palm, Elaeis guineensis (Arecaceae) in Central and South America. The family Tachinidae (Diptera) comprises flies that are parasitoids of many insect pests, mainly from the order Lepidoptera. However, host records for tachinids are still relatively scarce. In the present work, we report the occurrence of Belvosia sp. aff. williamsi (Diptera: Tachinidae: Exoristinae: Goniini) and Leptostylum oligothrix (Diptera: Tachinidae: Exoristinae: Blondeliini) parasitizing caterpillars of A. liberia in E. guineensis in the municipality of Tailândia, state of Pará, Brazil. This is the first record of the parasitism of A. liberia by Leptostylum in Brazil, as well as by Belvosia in the world. Lepidoptera (Lepidoptera Saturniidae palm Arecaceae (Arecaceae America Diptera (Diptera pests However scarce work sp aff Exoristinae Goniini Blondeliini A E Tailândia Pará Brazil world

https://doi.org/10.1590/1809-4392202201361

Chuva de sementes em uma região ecotonal entre Cerrado e Caatinga no Piauí, Brasil
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Morais, Rodrigo Ferreira

; Macedo, Maria Thamiris de Sousa

; Ibiapina, Ronaldo de Araújo

; Santiago Junior, Luiz Carlos

; Teixeira, Jefferson da Silva

; Morais, Fernando Ferreira de

; Sousa Júnior, José Ribamar

Ciência Florestal

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apr 2022, Volume 32 N. 2 Pages 673 - 697

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo A investigação da chuva de sementes pode fornecer informações úteis sobre a distribuição espacial, densidade e riqueza das espécies. O objetivo deste trabalho foi amostrar a chuva de sementes em Capões com presença e ausência de Copernicia prunifera (Carnaúba), caracterizar as sementes quanto à síndrome de dispersão e forma de vida, explorar a relação entre os totais pluviométricos mensais com a densidade e número de espécies da chuva de sementes e a estacionalidade na deposição de sementes. O estudo foi realizado em 20 Capões, sendo 10 com presença e 10 com ausência de Carnaúba. Cada Capão recebeu três coletores com área de 0,50 m2. Foram coletados 1.666 diásporos (55,5 sementes/m2) pertencentes a 17 famílias e 32 espécies. Houve relação negativa entre pluviosidade e número de sementes (r = -0,73 e p<0,05) e, entre pluviosidade e número de espécies da chuva de sementes (r = -0,78 e p<0,01). Houve aumento no número de espécies da chuva de sementes com o aumento de sementes da chuva de sementes (r = 0,74 e p< 0,001). Foram levantadas 908 sementes zoocóricas distribuídas em 12 espécies, anemocoria 502 sementes e 12 espécies e autocórica 256 sementes e sete espécies. As espécies arbóreas tiveram 895 sementes distribuídas em 12 espécies, os arbustos 574 sementes e 10 espécies, as Lianas 133 sementes e sete espécies e palmeiras com 61 sementes e duas espécies. As síndromes de dispersão anemocórica e zoocórica foram predominantes no período seco e zoocoria em todos os meses. Foi observada diferença na composição de espécies da chuva de sementes entre os Capões com presença e ausência de Carnaúba. A distância entre os Capões não influenciou na composição da chuva de sementes (Mantel r = -0,11e p = 0,74). Não houve relação entre áreas dos Capões com o número de sementes da chuva de sementes (R2 = 0,013 e p = 0,95).

Abstract Studies on seed rain can provide useful information on the spatial distribution, density, and richness of species. This study aimed to sample the seed rain in “capões” with the presence and absence of Copernicia prunifera (Carnaúba), characterizing the seeds as for their dispersion syndrome and life forms, and explore the relationship between the monthly rainfall totals and the density and number of species in the seed rain and the seasonality in seed deposition. The research was conducted in 20 capões, (10 with the presence and 10 with the absence of Copernicia prunifera). Three collectors of 0.50 m2 were placed in each capão. A total of 1,666 diaspores (55.5 seeds/m2), belonging to 17 families and 32 species, were collected. There was a negative relationship between rainfall and the number of seeds (r = -0.73 and p<0.05) and between rainfall and number of species in the seed rain (r = -0.78 and p<0.01). There was an increase in the number of species in the seed rain with an increase in the number of seeds (r = 0.74 and p<0.001). Twelve zoochoric, 12 anemochoric, and 7 autochoric species were recorded, which accounted for 908, 502, and 256 seeds, respectively. Trees had 895 seeds collected, distributed in 12 species, followed by shrubs (574 seeds and 10 species), lianas (133 seeds and 7 species), and palms (61 seeds and 2 species). Anemochoric and zoochoric dispersion syndromes predominated in the dry period, with a predominance of zoochory in all months. There was a difference in the species composition in the seed rain between the capões with the presence and with the absence of Copernicia prunifera. The distance between the capões did not influence the seed rain composition (Mantel r = -0.11 and p = 0.74). There was no relationship between areas of capões and the number of seeds in the seed rain (R2 = 0.013 and p = 0.95).

https://doi.org/10.5902/1980509846859

Assessment and Associations between Quality of Life and Risk of Suicide
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Melo, Cynthia de Freitas

; Vasconcelos Filho, José Eurico de

; Costa, Icaro Moreira

; Cavalcante, Ana Karine Sousa

; Silva, Sabrina Magalhães Martins da

; Freitas Filho, Ronaldo Almeida de

Psico-USF

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jan 2022, Volume 27 N. 1 Pages 61 - 72

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo Este estudo objetivou verificar em que medida os níveis de qualidade de vida se relacionam e influenciam os índices de risco de suicídio. Realizou-se uma pesquisa descritiva, correlacional, de abordagem quantitativa. Contou-se com uma amostra não probabilística composta por 11.863 participantes - brasileiros e maiores de 18 anos, que responderam à Risk Assessment Suicide Scale (RASS) e ao Word Health Organization Quality of Life Instrument Bref(WHOQOL-bref), cujos dados foram analisados por meio de estatística descritiva, correlação de Spearman e regressão linear multivariada pormeio do Statistical Package for Social Science (SPSS). Os resultados identificam correlações negativas, moderadas e significativas entre os construtos; e que os domínios de qualidade de vida influenciam em 47,8% as variações nos índices de risco de suicídio, constatando que o domínio psicológico é o mais relevante dentro do modelo explicativo criado. Conclui-se a necessidade de políticas públicas para melhoria da qualidade de vida e prevenção de suicídio.

Abstract This study aimed to verify the extent to which the levels of quality of life are related to and influence suicide risk indices. A descriptive, correlational, quantitative research was performed. A non-probabilistic sample was used which was composed of 11,863 Brazilian participants all over 18 years old, who responded to the Risk Assessment Suicide Scale (RASS) and the World Health Organization Quality of Life BREF Instrument (WHOQOL-BREF), and whose data were analyzed by using descriptive statistics, the Spearman correlation and multiple linear regression using the Statistical Package for Social Sciences (SPSS). The results identify negative, moderate and significant correlations between the constructs, and that the domains of quality of life influence 47.8% of the variations in the suicide risk indices, confirming that the psychological domain is the most relevant within the explanatory model created. The conclusion is that there is a the need for public policies to improve the quality of life and prevent suicide.

Resumen Este estudio objetivó comprobar hasta qué medida los niveles de calidad de vida se relacionan e influyen en las tasas de riesgo de suicidio. Se realizó una investigación descriptiva, correlacional y cuantitativa. Hubo una muestra no probabilística compuesta por 11.863 participantes brasileños mayores de 18 años, que respondieron a la Risk Assessment Suicide Scale (RASS) y al Word Health Organization Quality of Life Instrument Bref(WHOQOL-bref), cuyos datos fueron analizados mediante estadística descriptiva, correlación de Spearman y regresión lineal multivariante en Statistical Package for Social Science (SPSS). Los resultados identifican correlaciones negativas, moderadas y significativas entre los constructos; y que los dominios de calidad de vida influyen en un 47,8% en las variaciones de los índices de riesgo de suicidio, encontrando que el dominio psicológico es el más relevante dentro del modelo explicativo creado. Estos hallazgos revelan la necesidad de políticas públicas para mejorar la calidad de vida y prevenir el suicidio.

https://doi.org/10.1590/1413-82712022270105

Evaluation of the Use of Microwave Energy on The Reduction of Iron Ore and Steelmaking Mill Scale Composite Self-Reducing Mixtures
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Silva, Leonardo Martins da

; Eugênio, Tamara Fernandes

; Medeiros, Giulio Antunes de

; Medeiros, Ronaldo Gomes de Castro

; Freitas, Patrícia Guimarães Monteiro de

; Castro, José Adilson de

Materials Research

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2022, Volume 25 elocation e20210446

Abstract: En | Text: En | PDF: En

With the growing industrialization, there is a constant increase in the world demand for steel, causing an increase on extraction of low-grade iron ores, which bear high levels of impurities. A feasible alternative is the use of residues from steel rolling processes (steelmaking mill scale) generated in the steel industry, which are composed of iron oxides consisting mainly of wustite (FeO), hematite (Fe2O3) and magnetite (Fe3O4). In line with the recycling of wastes, the application of heating by microwave energy in ironmaking processes consists in a promising new method developed in recent decades and is considered a cleaner technique. Therefore, this study aims to evaluate the self-reduction of mixtures composed of iron ore and steelmaking mill scale as iron source, together with coke fines as carbon source, heated using microwave energy. Through the rotational central composite design technique, it was possible to evaluate the best conditions for the use of steelmaking scale residue as well as the effect of the applied microwave energy power. The results indicated that the developed process has relevant utility with up to 41.48% of reduction obtained. The outcomes contribute to a better understanding of iron recovery from steelmaking residues in reduction processes using microwave energy for heating, providing significant insight for the development of new clean technologies.

https://doi.org/10.1590/1980-5373-mr-2021-0446

Control of microbial growth and lipid oxidation on beef steak using a cashew nut shell liquid (CNSL)-based edible coating treatment
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LINO, Larruama Priscylla Fernandes de Vasconcelos

; PEREIRA FILHO, José Morais

; SOUZA, Marthyna Pereira de

; ARAÚJO, Débora Gomes de Sousa

; OLIVEIRA, Juliana Paula Felipe de

; SILVA FILHO, Edson Cavalcanti da

; SILVA, André Leandro da

; MAZZETTO, Selma Elaine

; OLIVEIRA, Ronaldo Lopes

; ROCHA, Karla Nayalle de Souza

; MOURA, José Fábio Paulino de

; BEZERRA, Leilson Rocha

Food Science and Technology

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2022, Volume 42 elocation e06822

Abstract: En | Text: En | PDF: En

Abstract Evaluate of cashew nut shell liquid (alginate-CNSL) on TBARS, physicochemical attributes and microbial growing of beef steak was investigated. Three edible coating treatments were prepared: (1) control (uncoating); (2) sodium alginate coating (no additive); and (3) active coatings of sodium alginate added cashew nut shell liquid (alginate-CNSL) at 1% into. Color indexes and water holding capacity were not affected by coating treatments. The pH of the beef samples from the control treatment increased at storage time, and the beef involved with alginate-CNSL coating maintained a pH stable. Alginate-CNSL coating promoted cooking loss lower after 3rd day of storage. Alginate-CNSL coating promoted a lower shear force decrease compared at control and sodium alginate coating. Alginate-CNSL coating reduced lipid oxidation (TBARS) and microbial growing (mesophiles and psychrophiles counts) in beef compared others treatments. Active coating from CNSL (1%) improved the beef preservation, reducing lipid oxidation and microbial growing, until the 6th day of storage stability.

https://doi.org/10.1590/fst.06822

Three-dimensional geological modeling of the Itataia Phosphate-Uranium Deposit (Ceará, Brazil)
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Freire, Ronaldo Cavalcante

; Veríssimo, Cesar Ulisses Vieira

; Parente, Clovis Vaz

; Nogueira Neto, José de Araújo

; Castro, Givaldo Lessa

; Silva, José Roberto de Alcântara e

Brazilian Journal of Geology

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2022, Volume 52 N. 3 elocation e20210022

Abstract: En | Text: En | PDF: En

Abstract The Itataia phosphate-uranium deposit is located in the northwest segment of the Borborema Province in the Ceará Central Domain. The ore mineral is uranium-enriched microcrystalline collophanite apatite that occurs in massive bodies and lenses, stockworks, as well as hydrothermal and karst breccias associated with marble, calc-silicate rocks and gneisses of the Itataia Group. The deformational history of the deposit includes ductile structures developed in the final stages of thrust tectonics linked to the Brasilian orogeny and later brittle phases related to extensional tectonics, which influenced phosphorus and uranium remobilization and the formation of ore bodies. The main uranium anomaly coincides with the upper part of the Serrote da Igreja hill, bordered to the north by an E-W trending subvertical fault scarp that controls a wide valley. Geometric modeling of the geological data of the deposit provides a three-dimensional view of the geometry of ore bodies, distribution of host rock and faults that propagate beneath the surface and control mineralization, as well as the upper and lower limits of surface weathering. The three-dimensional geometric model using the GoCAD software served as a powerful tool for the analysis of the geology of the Itataia deposit, highlighting the geometry of rocks and ore bodies and the processes involved in the genesis of phosphate-uranium mineralization.

https://doi.org/10.1590/2317-4889202220210022

Recommendations by the Scientific Department of Neuroimmunology of the Brazilian Academy of Neurology (DCNI/ABN) and the Brazilian Committee for Treatment and Research in Multiple Sclerosis and Neuroimmunological Diseases (BCTRIMS) on vaccination in general and specifically against SARS-CoV-2 for patients with demyelinating diseases of the central nervous system
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Becker, Jefferson

; Ferreira, Lis Campos

; Damasceno, Alfredo

; Bichuetti, Denis Bernardi

; Christo, Paulo Pereira

; Callegaro, Dagoberto

; Peixoto, Marco Aurélio Lana

; Sousa, Nise Alessandra De Carvalho

; Almeida, Sérgio Monteiro De

; Adoni, Tarso

; Santiago-Amaral, Juliana

; Junqueira, Thiago

; Pereira, Samira Luisa Apóstolos

; Gomes, Ana Beatriz Ayroza Galvão Ribeiro

; Pitombeira, Milena

; Paolilo, Renata Barbosa

; Grzesiuk, Anderson Kuntz

; Piccolo, Ana Claudia

; D´Almeida, José Arthur Costa

; Gomes Neto, Antonio Pereira

; Oliveira, Augusto Cesar Penalva De

; Oliveira, Bianca Santos De

; Tauil, Carlos Bernardo

; Vasconcelos, Claudia Ferreira

; Kaimen-Maciel, Damacio

; Varela, Daniel

; Diniz, Denise Sisterolli

; Oliveira, Enedina Maria Lobato De

; Malfetano, Fabiola Rachid

; Borges, Fernando Elias

; Figueira, Fernando Faria Andrade

; Gondim, Francisco De Assis Aquino

; Passos, Giordani Rodrigues Dos

; Silva, Guilherme Diogo

; Olival, Guilherme Sciascia Do

; Santos, Gutemberg Augusto Cruz Dos

; Ruocco, Heloisa Helena

; Sato, Henry Koiti

; Soares Neto, Herval Ribeiro

; Cortoni Calia, Leandro

; Gonçalves, Marcus Vinícius Magno

; Vecino, Maria Cecilia Aragón De

; Pimentel, Maria Lucia Vellutini

; Ribeiro, Marlise De Castro

; Boaventura, Mateus

; Parolin, Mônica Koncke Fiuza

; Melo, Renata Brant De Souza

; Lázaro, Robson

; Thomaz, Rodrigo Barbosa

; Kleinpaul, Rodrigo

; Dias, Ronaldo Maciel

; Gomes, Sidney

; Lucatto, Simone Abrante

; Alves-Leon, Soniza Vieira

; Fukuda, Thiago

; Ribeiro, Taysa Alexandrino Gonsalves Jubé

; Winckler, Thereza Cristina D’ávila

; Fragoso, Yara Dadalti

; Nascimento, Osvaldo José Moreira Do

; Ferreira, Maria Lucia Brito

; Mendes, Maria Fernanda

; Brum, Doralina Guimarães

; Glehn, Felipe Von

Arquivos de Neuro-Psiquiatria

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nov 2021, Volume 79 N. 11 Pages 1049 - 1061

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O DC de Neuroimunologia da ABN e o BCTRIMS trazem, nesse documento, as recomendações sobre vacinação da população com doenças desmielinizantes do sistema nervoso central (SNC) contra infecções em geral e contra o coronavírus da síndrome respiratória aguda grave 2 (SARS-CoV-2), causador da COVID-19. Destaca-se a gravidade do atual momento frente ao avanço da COVID-19 em nosso País, o que torna mais evidente e importante a criação de guia de referência para orientação aos médicos, pacientes e autoridades de saúde pública quanto à vacinação, meio efetivo e seguro no controle de determinadas doenças infecciosa. O DCNI/ABN e o BCTRIMS recomendam que os pacientes com doenças desmielinizantes do SNC (ex., EM e NMOSD) sejam constantemente monitorados, quanto a atualização do seu calendário vacinal, especialmente, no início ou antes da mudança do tratamento com uma droga modificadora de doença (DMD). É importante também salientar que as vacinas são seguras e os médicos devem estimular o seu uso em todos os pacientes. Evidentemente, deve ser dada especial atenção às vacinas com vírus vivos atenuados. Por fim, é importante que os médicos verifiquem qual DMD o paciente está em uso e quando foi feita a sua última dose, pois cada fármaco pode interagir de forma diferente com a indução da resposta imune.

ABSTRACT The Scientific Department of Neuroimmunology of the Brazilian Academy of Neurology (DCNI/ABN) and Brazilian Committee for Treatment and Research in Multiple Sclerosis and Neuroimmunological Diseases (BCTRIMS) provide recommendations in this document for vaccination of the population with demyelinating diseases of the central nervous system (CNS) against infections in general and against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes COVID-19. We emphasize the seriousness of the current situation in view of the spread of COVID-19 in our country. Therefore, reference guides on vaccination for clinicians, patients, and public health authorities are particularly important to prevent some infectious diseases. The DCNI/ABN and BCTRIMS recommend that patients with CNS demyelinating diseases (e.g., MS and NMOSD) be continually monitored for updates to their vaccination schedule, especially at the beginning or before a change in treatment with a disease modifying drug (DMD). It is also important to note that vaccines are safe, and physicians should encourage their use in all patients. Clearly, special care should be taken when live attenuated viruses are involved. Finally, it is important for physicians to verify which DMD the patient is receiving and when the last dose was taken, as each drug may affect the induction of immune response differently.

https://doi.org/10.1590/0004-282x-anp-2021-0162 1 downloads

10.

Diretrizes da Sociedade Brasileira de Cardiologia sobre Angina Instável e Infarto Agudo do Miocárdio sem Supradesnível do Segmento ST – 2021
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Nicolau, José Carlos

; Feitosa Filho, Gilson Soares

; Petriz, João Luiz

; Furtado, Remo Holanda de Mendonça

; Précoma, Dalton Bertolim

; Lemke, Walmor

; Lopes, Renato Delascio

; Timerman, Ari

; Marin Neto, José A.

; Bezerra Neto, Luiz

; Gomes, Bruno Ferraz de Oliveira

; Santos, Eduardo Cavalcanti Lapa

; Piegas, Leopoldo Soares

; Soeiro, Alexandre de Matos

; Negri, Alexandre Jorge de Andrade

; Franci, Andre

; Markman Filho, Brivaldo

; Baccaro, Bruno Mendonça

; Montenegro, Carlos Eduardo Lucena

; Rochitte, Carlos Eduardo

; Barbosa, Carlos José Dornas Gonçalves

; Virgens, Cláudio Marcelo Bittencourt das

; Stefanini, Edson

; Manenti, Euler Roberto Fernandes

; Lima, Felipe Gallego

; Monteiro Júnior, Francisco das Chagas

; Correa Filho, Harry

; Pena, Henrique Patrus Mundim

; Pinto, Ibraim Masciarelli Francisco

; Falcão, João Luiz de Alencar Araripe

; Sena, Joberto Pinheiro

; Peixoto, José Maria

; Souza, Juliana Ascenção de

; Silva, Leonardo Sara da

; Maia, Lilia Nigro

; Ohe, Louis Nakayama

; Baracioli, Luciano Moreira

; Dallan, Luís Alberto de Oliveira

; Dallan, Luis Augusto Palma

; Mattos, Luiz Alberto Piva e

; Bodanese, Luiz Carlos

; Ritt, Luiz Eduardo Fonteles

; Canesin, Manoel Fernandes

; Rivas, Marcelo Bueno da Silva

; Franken, Marcelo

; Magalhães, Marcos José Gomes

; Oliveira Júnior, Múcio Tavares de

; Filgueiras Filho, Nivaldo Menezes

; Dutra, Oscar Pereira

; Coelho, Otávio Rizzi

; Leães, Paulo Ernesto

; Rossi, Paulo Roberto Ferreira

; Soares, Paulo Rogério

; Lemos Neto, Pedro Alves

; Farsky, Pedro Silvio

; Cavalcanti, Rafael Rebêlo C.

; Alves, Renato Jorge

; Kalil, Renato Abdala Karam

; Esporcatte, Roberto

; Marino, Roberto Luiz

; Giraldez, Roberto Rocha Corrêa Veiga

; Meneghelo, Romeu Sérgio

; Lima, Ronaldo de Souza Leão

; Ramos, Rui Fernando

; Falcão, Sandra Nivea dos Reis Saraiva

; Dalçóquio, Talia Falcão

; Lemke, Viviana de Mello Guzzo

; Chalela, William Azem

; Mathias Júnior, Wilson

Arquivos Brasileiros de Cardiologia

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jul 2021, Volume 117 N. 1 Pages 181 - 264

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20210180 3052 downloads

11.

Diretrizes Brasileiras de Hipertensão Arterial – 2020
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Barroso, Weimar Kunz Sebba

; Rodrigues, Cibele Isaac Saad

; Bortolotto, Luiz Aparecido

; Mota-Gomes, Marco Antônio

; Brandão, Andréa Araujo

; Feitosa, Audes Diógenes de Magalhães

; Machado, Carlos Alberto

; Poli-de-Figueiredo, Carlos Eduardo

; Amodeo, Celso

; Mion Júnior, Décio

; Barbosa, Eduardo Costa Duarte

; Nobre, Fernando

; Guimarães, Isabel Cristina Britto

; Vilela-Martin, José Fernando

; Yugar-Toledo, Juan Carlos

; Magalhães, Maria Eliane Campos

; Neves, Mário Fritsch Toros

; Jardim, Paulo César Brandão Veiga

; Miranda, Roberto Dischinger

; Póvoa, Rui Manuel dos Santos

; Fuchs, Sandra C

; Alessi, Alexandre

; Lucena, Alexandre Jorge Gomes de

; Avezum, Alvaro

; Sousa, Ana Luiza Lima

; Pio-Abreu, Andrea

; Sposito, Andrei Carvalho

; Pierin, Angela Maria Geraldo

; Paiva, Annelise Machado Gomes de

; Spinelli, Antonio Carlos de Souza

; Nogueira, Armando da Rocha

; Dinamarco, Nelson

; Eibel, Bruna

; Forjaz, Cláudia Lúcia de Moraes

; Zanini, Claudia Regina de Oliveira

; Souza, Cristiane Bueno de

; Souza, Dilma do Socorro Moraes de

; Nilson, Eduardo Augusto Fernandes

; Costa, Elisa Franco de Assis

; Freitas, Elizabete Viana de

; Duarte, Elizabeth da Rosa

; Muxfeldt, Elizabeth Silaid

; Lima Júnior, Emilton

; Campana, Erika Maria Gonçalves

; Cesarino, Evandro José

; Marques, Fabiana

; Argenta, Fábio

; Consolim-Colombo, Fernanda Marciano

; Baptista, Fernanda Spadotto

; Almeida, Fernando Antonio de

; Borelli, Flávio Antonio de Oliveira

; Fuchs, Flávio Danni

; Plavnik, Frida Liane

; Salles, Gil Fernando

; Feitosa, Gilson Soares

; Silva, Giovanio Vieira da

; Guerra, Grazia Maria

; Moreno Júnior, Heitor

; Finimundi, Helius Carlos

; Back, Isabela de Carlos

; Oliveira Filho, João Bosco de

; Gemelli, João Roberto

; Mill, José Geraldo

; Ribeiro, José Marcio

; Lotaif, Leda A. Daud

; Costa, Lilian Soares da

; Magalhães, Lucélia Batista Neves Cunha

; Drager, Luciano Ferreira

; Martin, Luis Cuadrado

; Scala, Luiz César Nazário

; Almeida, Madson Q.

; Gowdak, Marcia Maria Godoy

; Klein, Marcia Regina Simas Torres

; Malachias, Marcus Vinícius Bolívar

; Kuschnir, Maria Cristina Caetano

; Pinheiro, Maria Eliete

; Borba, Mario Henrique Elesbão de

; Moreira Filho, Osni

; Passarelli Júnior, Oswaldo

; Coelho, Otavio Rizzi

; Vitorino, Priscila Valverde de Oliveira

; Ribeiro Junior, Renault Mattos

; Esporcatte, Roberto

; Franco, Roberto

; Pedrosa, Rodrigo

; Mulinari, Rogerio Andrade

; Paula, Rogério Baumgratz de

; Okawa, Rogério Toshiro Passos

; Rosa, Ronaldo Fernandes

; Amaral, Sandra Lia do

; Ferreira-Filho, Sebastião R.

; Kaiser, Sergio Emanuel

; Jardim, Thiago de Souza Veiga

; Guimarães, Vanildo

; Koch, Vera H.

; Oigman, Wille

; Nadruz, Wilson

Arquivos Brasileiros de Cardiologia

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mar 2021, Volume 116 N. 3 Pages 516 - 658

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20201238 10948 downloads

12.

Prognosis of Heart Failure with Preserved Ejection Fraction in Primary Care by the H2FPEF Score
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Jorge, Antonio Jose Lagoeiro

; Rosa, Maria Luiza Garcia

; Martins, Wolney de Andrade

; Leite, Adson

; Correia, Dayse Mary da Silva

; Saad, Maria Auxiliadora Nogueira

; Villacorta, Humberto

; Chermont, Sergio

; Gismondi, Ronaldo Altenburg

; Almeida, Breno Macedo

; Mesquita, Evandro Tinoco

International Journal of Cardiovascular Sciences

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dec 2020, Volume 33 N. 6 Pages 666 - 672

Abstract: En | Text: En | PDF: En

Abstract Background: Primary care physicians have difficulty dealing with patients who have HF with preserved LVEF(HFpEF). The prognosis of HFpEF is poor, and difficult to predict on primary care. Objective: The aim of the study is to apply the H2FPEF score to primary care patients and verify its power to assess the risk of death or hospitalization due to cardiovascular disease. Methods: This longitudinal study included 402 individuals, with signs or symptoms of HF, aged≥45 years and, underwent an evaluation which included clinical examination, BNP and echocardiogram. The diagnosis of HFpEF was confirmed by the criteria of the European Society of Cardiology. After five years, the patients were reassessed as to the occurrence of the composite outcome, death from any cause or hospitalization for cardiovascular disease. H2FPEF used six variables: body mass index, medications for hypertension, age, pulmonary artery systolic pressure, atrial fibrillation and E/e' ratio ranged from 0 to 9 points. The level of statistical significance was p<0.05. Results: HFpEF was diagnosed in 58(14.4%). Among patients with H2FPEF≥4, 30% had HFpEF and in those with a score≤4, HFpEF was present in 12%. Patients with HFpEF and H2FPEF≥4 had 53% of outcomes, whereas patients with HFpEF and a score ≤4 had a 21% of outcomes. BNP values were higher in patients with HFpEF compared to those without HFpEF(p<0.0001). Conclusion: H2FPEF≥4 indicated a worse prognosis in patients with HFpEF assisted in primary care. H2FPEF may be a simple and useful tool for risk stratification in patients with HFpEF at the primary care.

https://doi.org/10.36660/ijcs.20200076 430 downloads

13.

Seed germination and dormancy break in Eragrostis polytricha, a native Brazilian grass species with potential for recovery of degraded lands
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Saraiva, Diogo F.

; Paula, Cláudio C. de

; Moraes, Paulo José de

; Vinícius-Silva, Ronaldo

; Silva, Mariana M.

; Dias, Denise C.F.S.

; Botelho, Soraya A.

Acta Botanica Brasilica

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sep 2020, Volume 34 N. 3 Pages 497 - 504

Abstract: En | Text: En | PDF: En

ABSTRACT Ferruginous Rocky Outcrops have high levels of species richness and endemism, but have been threatened by several anthropic actions, especially mining. Eragrostis polytricha, a common grass species in the vegetation of these outcrops, has shown promising features for use in the recovery of mining areas. However, in order to fully understand the species’ potential for such use, its requirements for germination, seed dormancy break and seedling development must be determined. Thus, we aimed to: (1) assess the temperature conditions needed for seeds of E. polytricha to germinate; (2) evaluate the effects of KNO₃ in breaking seed dormancy; and (3) analyze the germination efficiency of seeds that are still in spikelets. The experiment included seven treatments: 15-35 ºC with KNO₃, 20-30 ºC with KNO₃, 15 ºC with KNO₃, 25 ºC with KNO₃, 35 ºC with KNO₃, 20-30 ºC with water, and 20-30 ºC with KNO₃ using spikelets. The treatments with alternating temperatures associated with KNO3 yielded the highest germination rates, suggesting that these two factors combined can break seed dormancy. Seeds inside spikelets exhibited a high germination percentage, and thus represent an interesting alternative for seedling production.

https://doi.org/10.1590/0102-33062019abb0381 965 downloads

14.

Tenofovir Disoproxil Fumarate: New Chemical Developments and Encouraging in vitro Biological Results for SARS-CoV-2
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Clososki, Giuliano C.

; Soldi, Rafael A.

; Silva, Rodrigo M. da

; Guaratini, Thais

; Lopes, José N. C.

; Pereira, Pâmela R. R.

; Lopes, João L. C.

; Santos, Thiago dos

; Martins, Ronaldo B.

; Costa, Cristina S.

; Carvalho, Andréia N. de

; da Silva, Luis L. P.

; Arruda, Eurico

; Lopes, Norberto P.

Journal of the Brazilian Chemical Society

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aug 2020, Volume 31 N. 8 Pages 1552 - 1556

Abstract: En | Text: En | PDF: En

The recent emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led society to live with a serious public health problem. In this sense, repositioning of antiretrovirals has captured the attention of the scientific community. Tenofovir disoproxil fumarate (TDF) is an antiretroviral compound that is used to treat acquired immune deficiency syndrome (AIDS) and hepatitis B. In this short report, we present a scale-up investigation of TDF by in situ infrared spectroscopy monitoring and a forced degradation study to describe a new degradation product. Finally, we have evaluated TDF in vitro for SARS-CoV-2 for the first time foreseeing the using of this medicine in pre-clinical and clinical investigations for the COVID-19 (coronavirus disease 2019) treatment.

https://doi.org/10.21577/0103-5053.20200106 1823 downloads

15.

Reconstrução mamária com implante: confecção de bolsa com retalho reverso de músculo serrátil anterior
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ALMEIDA, AUGUSTO CÉSAR DE MELO

; SILVA FILHO, ALOÍSIO FERREIRA DA

; ROSSIGNOLI, RONALDO SAPI

; PEREIRA, NÁRLEI AMARANTES

; FONSECA, REBECA PAOHWA LIU

; PORTUGAL, ERICK HORTA

; OLIVEIRA FILHO, RENATO SANTOS DE

; ALVES, JOSÉ CARLOS RIBEIRO RESENDE

Revista Brasileira de Cirurgia Plástica

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jan 2020, Volume 35 N. 1 Pages 52 - 59

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Introduction: Immediate breast reconstruction plays an important role in the treatment of breast cancer and relatively promotes patients’ emotional and physical recovery. It may be difficult to cover the entire prosthesis with a muscle flap in single-stage breast reconstructions based on a permanent implant. This study aimed to present a muscle pocket for the implant using a reverse anterior serratus muscle flap associated with submuscular dissection of the pectoralis major muscle. Methods: This was a prospective study comprising 61 patients undergoing mastectomy followed by immediate reconstruction (74 reconstructions) with implant and anterior serratus muscle reverse flap associated with submuscular pectoralis dissection between January 2017 and July 2018. In this study, age, adjuvant and neoadjuvant therapies, implant volume, length of hospital stay, follow-up, and complications, including functional deficit and reconstruction failure, were analyzed. Results: The technique described was used to operate 74 patients with a mean age of 49.2 years. The volume of the implant varied from 200 to 500 cc, and the mean follow-up time was 14.9 months. Complications such as hematoma, suture dehiscence, skin flap necrosis, and implant extrusion were observed in 14 patients (18.9%). Conclusion: In most cases, breast reconstruction with an anterior serratus muscle reverse flap associated with submuscular dissection of the pectoralis major muscle allows the complete muscle coverage of the implant, reduces the occurrence of major surgical complications, and has a good aesthetic result.

RESUMO Introdução: A reconstrução mamária imediata desempenha papel importante no tratamento do câncer de mama, permitindo uma recuperação emocional e física, ainda que parcial, das pacientes. Nas reconstruções mamárias em único estágio, baseada em implante permanente, pode ser difícil cobrir toda a prótese com retalho muscular. O objetivo do estudo é apresentar a realização de uma bolsa muscular para implante através do retalho reverso do músculo serrátil anterior associada à dissecção submuscular do músculo peitoral maior. Métodos: Foi realizado um estudo prospectivo com 61 pacientes submetidas à mastectomia seguida de reconstrução imediata (74 reconstruções) com implante e retalho reverso do músculo serrátil anterior associado à dissecção submuscular do peitoral, entre janeiro de 2017 e julho de 2018. Foram analisados a idade, terapia adjuvante e neoadjuvante, volume do implante, tempo de internação hospitalar, seguimento e complicações, incluindo déficit funcional e falha na reconstrução. Resultados: 74 pacientes foram operadas pela técnica descrita com idade média de 49,2 anos. O volume do implante variou de 200 a 500cc e o tempo médio de proservação foi de 14,9 meses. 14 pacientes (18,9%) apresentaram complicações como hematoma, deiscência de sutura, necrose de retalho cutâneo e extrusão do implante. Conclusão: A reconstrução mamária com retalho reverso do músculo serrátil anterior associado à dissecção submuscular do peitoral maior permite, na grande maioria dos casos, cobertura muscular completa do implante, redução de complicações cirúrgicas maiores e bom aspecto estético.

https://doi.org/10.5935/2177-1235.2020rbcp0009

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