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Uvea Metastasis of Breast Carcinoma

SUMMARY

The systemic and the ocular metastasis of 13 patients with breast carcinoma were cronologically documented from the diagnosis of the primary disease. The visual acuity pre and post treatment were documented as well as the ocular findings of the metastatic disease. All the intraocular lesions were treated by irradiation (externai beam radiotherapy) anel the dose varied from 30 to 50 Gy.

The eye was the first site of metastasis in 5 cases (38.5%). The posterior pote was the preferential site of metastasis, although, lesions of ciliary body and iris were also seen. Three patients developed bilateral intraocular tumor. Seven patients had tumor infiltration of the optic nerve head. Persistent retinal detachment, secundary glaucoma, cataract and dry eye were the complications associated to the radiation.

The visual prognosis was directly related to the size of the tumor. The systemic prognosis was relatively poor. The mean survival time was 11 months from the diagnosis of ocular lesion.

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