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The Application of Taguchi Method to Optimize Pellet Quality in Broiler Feeds

ABSTRACT.

The aim of this experiment was to optimize pellet quality by changing different levels of moisture, production rate, grain particle size and conditioning temperature using Taguchi method. In this experiment A 43 fractional factorial arrangement using Taguchi method was conducted in broiler starter, Grower and finisher feeds with three production rates (3.5, 4 and 4.5 ton h-1), three steam conditioning temperatures (65, 75 and 85°C), three particle sizes that were achieved by grinding the whole grains in the hammer mill to pass through 6, 6.5 and 7.0 mm sieves respectively, and three moisture content (0, 2.5 and 5%) that were added to the broiler feed in the mixer. During the production process, sampling was done and then PDI and hardness were evaluated in grower and finisher feeds). Results of this experiment showed a significant effect of processing parameters on PDI and hardness. In Conclusion the major finding of this experiment was that the Taguchi method can be used to find the best combination of factors for optimal pellet quality by testing only a fraction of the treatments of the full factorial design.

Keywords:
processing parameters; PDI; hardness; feed physical quality; broiler; pellet

Introduction

Broiler growth and feed efficiency are improved by pelleting feed. These performance improvements are attributed to decreased feed wastage, reduced selective feeding, decreased ingredient segregation, less time and energy expended for eating, destruction of pathogenic organisms, thermal modification of starch and protein and improved feed palatability. Poor quality of obtained crumble or pellets will result in a reduction of the feed intake and poorer biological performance.

On the farm, attention should be given to managing feed distribution to minimize physical deterioration in crumble and pellets (Ross Broiler Management Handbook, 2014Ross Broiler Management Handbook. (2014). Provision of Feed and Water (p. 28-32). Retrieved from https://www.academia.edu/36366118/Ross_Broiler_Handbook_2014i_EN
https://www.academia.edu/36366118/Ross_B...
). The main aim of the pelleting process is to agglomeration small particles into larger particles by use of a mechanical pressure process in combination with moisture, heat (Cutlip et al., 2008Cutlip, S. E., Hott, J. M., Buchanan, N. P., Rack, A. L., Latshaw, J. D., & Moritz, J. S. (2008). The effect of steam conditioning practices on pellet quality and growing broiler nutritional value. The Journal of Applied Poultry Research, 17(2), 249-261. DOI: https://doi.org/10.3382/japr.2007-00081
https://doi.org/https://doi.org/10.3382/...
). This combination results in thermo mechanical changes in feed constituents and an improvement in feed form. Offering feed to birds in pellet increases the economy by improved animal performance and decreasing the feed conversion ratio (Wamsley & Moritz, 2013Wamsley, K. G. S., & Moritz, J. S. (2013). Resolving poor pellet quality and maintaining amino acid digestibility in commercial turkey diet feed manufacture. Journal of Applied Poultry Research, 22(3), 439-446. DOI: https://doi.org/10.3382/japr.2012-00657
https://doi.org/https://doi.org/10.3382/...
).

The need to achieve high physical quality and to reduce potential levels of feed-borne pathogens such as Salmonella has led to the application of relatively high conditioning temperatures during conventional hydrothermal processes, a practice that does not favor high nutrient utilization and stability of heat sensitive feed additives (Kiarie & Mills, 2019Kiarie, E. G., & Mills, A. (2019). Role of feed processing on gut health and function in pigs and poultry: conundrum of optimal particle size and hydrothermal regimens.Frontiers in Veterinary Science, 6, 19. DOI: https://doi.org/10.3389/fvets.2019.00019
https://doi.org/https://doi.org/10.3389/...
). Recently, feed additives significantly reduced the S. enteritidis population in both ileum and cecum (Moharreri, Vakili, Oskoueian, & Rajabzadeh, 2022Moharreri, M., Vakili, R., Oskoueian, E., & Rajabzadeh, G. (2022). Evaluation of Microencapsulated Essential Oils in Broilers Challenged with Salmonella Enteritidis: A Focus on the Body’s Antioxidant Status, Gut Microbiology, and Morphology.Archives of Razi Institute, 77(2), 629-639. DOI: https://doi.org/10.22092/ARI.2021.354334.1634
https://doi.org/https://doi.org/10.22092...
).It is essential to optimize pellet quality by changing different levels of pelleting process. Paying attention to form and feed particle size is vital in improving production efficiency, nutrient utilization and reducing the burden of environmental pollution.In laying hens, some trace minerals and extracts in egg contents were retained differently due to feed (Niknia, Vakili, & Tahmasbi, 2022Niknia, A. D., Vakili, R., & Tahmasbi, A. M. (2022). Zinc supplementation improves antioxidant status, and organic zinc is more efficient than inorganic zinc in improving the bone strength of aged laying hens. Veterinary Medicine and Science, 8(5), 2040-2049. DOI: http://dx.doi.org/10.1002/vms3.896
https://doi.org/http://dx.doi.org/10.100...
; Vakili, Toroghian, & Torshizi., 2022Vakili, R., Toroghian, M., & Torshizi, M. E. (2022). Saffron extract feed improves the antioxidant status of laying hens and the inhibitory effect on cancer cells (PC3 and MCF7) Growth. Veterinary Medicine and Science, 8(6), 2494-2503. DOI: https://doi.org/10.1002/vms3.910
https://doi.org/https://doi.org/10.1002/...
; Khoshbin, Vakili, & Tahmasbi, 2023Khoshbin, M. R., Vakili, R., & Tahmasbi, A. M. (2023). Manganese-methionine chelate improves antioxidant activity, immune system and egg manganese enrichment in the aged laying hens. Veterinary Medicine and Science, 9(1), 217-225. DOI: https://doi.org/10.1002/vms3.1008
https://doi.org/https://doi.org/10.1002/...
). According to Hafeez et al. (2015Hafeez, A., Mader, A., Ruhnke, I., Röhe, I., Boroojeni, F. G., Yousaf, M. S., ... Zentek, J. (2015). Implication of milling methods, thermal treatment, and particle size of feed in layers on mineral digestibility and retention of minerals in egg contents. Poultry Science, 94(2), 240-248. DOI: https://doi.org/10.3382/ps/peu070
https://doi.org/https://doi.org/10.3382/...
), in contrast to combinations of fine feed particles with mash and expandate forms, the retention of a few trace elements in egg contents (iron and zinc, respectively) was increased when the coarse particle size was combined with both the mash and expandate forms.

A successful experiment mainly depends on a proper design. The traditional method of process optimization of factors with interaction effects involves the study of these factors at different levels, which is costly, and labor and time intensive. A full factorial design is extensively used in agricultural and poultry science for the optimization of such factors and their interaction effects. The advantage of a full factorial design is that it is possible to calculate the main effects and all the possible multi-factor interactions of the factors, but the number of factors and their levels that can be tested is limited (Antony, 2003Antony, J. (2003). Design of experiments for engineers and scientists. Oxford, EN: Elsevier Science and Technology Books.).

Therefore, other statistical tools with a lower number of runs may replace full factorial designs. The Taguchi method is an easy statistical tool, which enables a maximum number of main effects to be estimated with a minimum number of experimental runs (Chung, Chen, & Hsieh, 2007Chung, C. C., Chen, H. H., & Hsieh, P. C. (2007). Application of Taguchi method to optimize monascus SPP. Culture Journal of Food Process Engineering, 30(2), 241-254. DOI: https://doi.org/10.1111/j.1745-4530.2007.00112.x
https://doi.org/https://doi.org/10.1111/...
; Roy, 2010Roy, R. K. (2010). A Primer on the Taguchi Method (2nd ed.). Dearborn, Mi: Society of Manufacturing Engineers.). The objective of the current study was to determine the effect of pelleting process based on manufacturing technique on pellet feed quality.

Material and methods

Experimental design and data collection

Factor Levels and Orthogonal Array

In the present work, four process parameters including production rate, temperature, humidity, and particle size varied at three levels were considered. The range of different factors and their levels used for this study are shown in Table 1.

Table 1
The L9 (34) Taguchi orthogonal array of the experimental design.

A modified orthogonal array of L9 is found to be appropriate and hence it was chosen. The orthogonal array of L9 (9 treatments) was selected based on the number of parameters and their levels via Minitab 16.1 software (Minitab Inc., State College, PA). Taguchi’s L9 orthogonal array was used as shown in Table 1. The composition of the diets and the amount of their nutrients are indicated in Table 2. Ross 308 nutrition guideline was used to formulate the diets (Ross Broiler Management Handbook, 2014Ross Broiler Management Handbook. (2014). Provision of Feed and Water (p. 28-32). Retrieved from https://www.academia.edu/36366118/Ross_Broiler_Handbook_2014i_EN
https://www.academia.edu/36366118/Ross_B...
).

Table 2
Composition of grower and finisher experimental diets.

The data collection was made in Zardaneh-Dizbad Co in the Nishabour, Iran (pellet mill made in Bulgaria, model 520/178). A 43 fractional factorial arrangement with 9 treatments was conducted in grower and finisher feeds with three production rate 220, 320 and 420 pellet feeder speeds (3.5, 4 and 4.5 ton h-1), three steam temperatures conditioning (65, 75 and 85°C), three particle sizes that were achieved by grinding the whole grains in the hammer mill to pass through 6, 6.5 and 7.0 mm sieves respectively, and three moisture content (0, 2.5 and 5%) that were added to broiler feed in the mixer.

During the production process, sampling was done at the end-point of production line. Pellet durability and pellet hardness determine with Holmen pellet tester (model NHP100) and Stable Micro Systems Texture Analyser (model XTplus100), respectively. The obtained pellet quality (PDI and hardness) values were converted to signal to noise (S/N) ratios that were used to find the optimal level of each factor. In this work, the optimized response variables were PDI and hardness, in which both should be increased as much as possible. Hence, the optimum parameter levels were those that gave maximum S/N values of the PDI and hardness.

Results and discussion

A Taguchi robust design method was used to identify the optimal condition and optimize pellet quality. The S/N and the main effects of each parameter for PDI quality in grower and finisher diets are shown in figures 1 and 2 respectively. Figure 3 shows the S/N and main effects of each parameter for hardness quality in grower and finisher diets. In both PDI and hardness, a greater S/N value corresponds to better pellet quality. Therefore, the optimal pellet quality is the combination of the level of each factor with the greatest S/N value. Results of this experiment showed a significant effect of processing parameters on PDI and hardness.

According to Itani and Svihus (2019Itani, K., & Svihus, B. (2019). Feed processing and structural components affect starch digestion dynamics in broiler chickens.British Poultry Science, 60(3), 246-255. DOI: https://doi.org/10.1080/00071668.2018.1556388
https://doi.org/https://doi.org/10.1080/...
) study, whilst pelleting molds mash diets to macro particles in the form of pellets, it simultaneously reduces the size of the micro-particles that constitute the intact pellet. A reduction in particle size due to pelleting has also been reported by Péron, Bastianelli, Oury, Gomez, and Carré (2005Péron, A., Bastianelli, D., Oury, F. X., Gomez, J., & Carré, B. (2005). Effects of food deprivation and particle size of ground wheat on digestibility of food components in broilers fed on a pelleted diet. British Poultry Science, 46(2), 223-230. DOI: https://doi.org/10.1080/00071660500066142
https://doi.org/https://doi.org/10.1080/...
).

Trials have shown that every 10% increase in fines (< 1 mm) results in a reduction of 40 g body weight at 35 days and therefore, the aim should be to minimize the amount of fine particles (< 1 mm) in the feed (Ross Broiler Management Handbook, 2014Ross Broiler Management Handbook. (2014). Provision of Feed and Water (p. 28-32). Retrieved from https://www.academia.edu/36366118/Ross_Broiler_Handbook_2014i_EN
https://www.academia.edu/36366118/Ross_B...
).

Figure 1
The means and S/N ratio graphs for optimization of PDI in grower diets.

Figure 2
The means and S/N ratio graphs for optimization of PDI in finisher diets.

Amerah, Ravindran, Lentle, and Thomas (2007Amerah, A. M., Ravindran, V., Lentle, R. G., & Thomas, D. G. (2007). Influence of feed particle size and feed form on the performance, energy utilization, digestive tract development, and digesta parameters of broiler starters. Poultry Science, 86, 2615-2623. ) showed that feed form had a greater influence on performance parameters than did particle size. Figure 1 shows that pellet durability was decreased by accelerating the production rate in grower feed. Although adding the humidity increased PDI, the addition of 2.5% moisture was better than 5%. Moritz et al. (2001Moritz, J. S., Beyer, R. S., Wilson, K. J., Cramer, K. R., McKinney, L. J., & Fairchild, F. J. (2001). Effect of moisture addition at the mixer to a corn-soybean based diet on broiler performance. Journal Apply Poultry, 10(4), 347-353. DOI: https://doi.org/10.1093/japr/10.4.347
https://doi.org/https://doi.org/10.1093/...
) reported that by adding moisture to the mash in a mixer, feed durability was increased. In our study the PDI raised by increasing the conditioning temperature after 24 hours of pellet production. The conventional pelleting process, increasing conditioning temperature can be performed by increasing the steam flow rate. More steam means more heat and moisture, the two primary perquisites needed for feed particle adhesion, thus improving pellet quality (Abdollahi, Ravindran, Wester, Ravindran, & Thomas, 2011Abdollahi, M. R., Ravindran, V., Wester, T. J., Ravindran, G., & Thomas, D. V. (2011). Influence of feed form and conditioning temperature on performance, apparent metabolisable energy and ileal digestibility of starch and nitrogen in broiler starters fed wheat-based diet. Animal Feed Science and Technology, 168(1-2), 88-99. DOI: https://doi.org/10.1016/j.anifeedsci.2011.03.014
https://doi.org/https://doi.org/10.1016/...
).

So according with Taguchi results, the best combination was the first level of production speed (220 rpm speed feeder), the third level of particle size (fine), the second level of addition of water (2.5%) and the third level of conditioner temperature (85°C) to improve PDI, respectively after 24 hours of pellet production in grower diets. These results are in agreement with Frederick et al and Buchanan and Moritz (2009Buchanan, N. P., & Moritz, J. S. (2009). Main effects and interactions of varying formulation protein, fiber, and moisture on feed manufacture and pellet quality. The Journal of Applied Poultry Research, 18, 274-283. DOI: https://doi.org/10.3382/japr.2008-00089
https://doi.org/https://doi.org/10.3382/...
) findings and rejected the Buchanan, Lilly and Moritz (2010a Buchanan, N. P., Lilly, K. G. S., & Moritz, J. S. (2010a). The effects of diet formulation, manufacturing technique, and antibiotic inclusion on broiler performance and intestinal morphology. The Journal of Applied Poultry Research, 19(2), 121-131. DOI: https://doi.org/10.3382/japr.2009-00071
https://doi.org/https://doi.org/10.3382/...
and bBuchanan, N. P., Lilly, K. G. S., & Moritz, J. S. (2010b). The effects of altering diet formulation and manufacturing technique on pellet quality. The Journal of Applied Poultry Research, 19, 112-120. DOI: https://doi.org/10.3382/japr.2009-00070
https://doi.org/https://doi.org/10.3382/...
) results. The physical quality of the pellets durability and hardness) was improved by increasing conditioning temperature from 69 to 78 and 86C° (Buchanan and Moritz, 2009Buchanan, N. P., & Moritz, J. S. (2009). Main effects and interactions of varying formulation protein, fiber, and moisture on feed manufacture and pellet quality. The Journal of Applied Poultry Research, 18, 274-283. DOI: https://doi.org/10.3382/japr.2008-00089
https://doi.org/https://doi.org/10.3382/...
).

In the finisher feed, the PDI increased by decreasing the production rate (Figure 2). Medium particle size had greater PDI. Adding the humidity increases the PDI, and adding 5% moisture to the mixer had the best PDI. The raising temperature increased pellet durability after one week of pellet production in finisher diets. So based on the Taguchi method, The best combination of finisher was the first level of production speed (220 rpm speed feeder), the second level of particle size (medium sieve), the second level of humidity addition (5%) and the third level of conditioner temperature (85°C) to improve pellet durability index, respectively.

Finisher pellet durability obtained one week after production showed almost the same trend (Figure 2). Only the best level of production speed, was the third level (feeder speed 420 rpm). Smaller feed particle size through fine grinding increases surface area, provides more contact points with adjoining particles, leads to faster penetration of heat and moisture to the core of particles, and results in better binding characteristics and higher quality pellets (Behnke, 2001; Dozier, 2003Dozier, W. A. (2003). Optimising the conditioning process. Feed Management, 54(9), 23-27. ; Löwe, 2005Lowe, R. (2005) Judging pellet stability as part of pellet quality. Feed Technology, 9, 15-19.).

Pellet hardness

Results of pellet hardness in grower and finisher feeds are shown in Figure 3. According to the Figures 3 the average S/N performance for optimizing pellet hardness index in grower has been shown that increasing pellet hardness decreased production speed. The smaller particle size, had greater hardness. Adding the humidity reduced pellet hardness. Also increases the temperature reduced pellet hardness. So according to the Taguchi method, the best combination was the first level of production speed (220 rpm speed feeder), the first level of particle size (fine), the first level of water addition (zero percent) and the second level of conditioner temperature (75°C), to improve the hardness index in grower.

Figure 3
The means and S/N ratio graphs for optimization of Hardness in grower and finisher diets; Speed 1=220, 2=320 and 3=420. Mo= Moisture; 1=0, 2=2.5 and 3=5. Tem= Temperature; 1=65, 2=75 and 3=85°C

In finisher, the best combination was obtained by the first level of production speed (220 rpm speed feeder), the first level of particle size (fine), the second level of water addition (2.5%) and the first level of conditioner temperature (65°C), to improve the hardness index.

Currently, there are no industry standards for manufacturing pellets. Each mill may operate using different diet formulations, ingredient particle sizes, steam pressures, conditioning temperatures, and production rates (Buchanan & Moritz, 2009Buchanan, N. P., & Moritz, J. S. (2009). Main effects and interactions of varying formulation protein, fiber, and moisture on feed manufacture and pellet quality. The Journal of Applied Poultry Research, 18, 274-283. DOI: https://doi.org/10.3382/japr.2008-00089
https://doi.org/https://doi.org/10.3382/...
). For example, in a survey conducted by Buchanan and Moritz (2009Buchanan, N. P., & Moritz, J. S. (2009). Main effects and interactions of varying formulation protein, fiber, and moisture on feed manufacture and pellet quality. The Journal of Applied Poultry Research, 18, 274-283. DOI: https://doi.org/10.3382/japr.2008-00089
https://doi.org/https://doi.org/10.3382/...
), commercial feed mills in the eastern United States used conditioning temperatures ranging from 68 to 91°C (155 to 195°F), die length-to die hole diameter ratios (LDR) ranging from 6.5 to 13.1, and production rates ranging from 907 to 14,882 metric tons/wk. (1,000 to 16,400 tons wk-1).

Variation in all these factors may affect the amount of heat and moisture that feed will accrue through the pelleting process. As a result, thermo mechanical changes in nutrients, such as starch gelatinization and protein denaturation, are widely variable. Inconsistency in manufacturing technique, coupled with constantly changing diet formulations, makes predicting and optimizing pellet quality difficult.

The results of our experiment showed that the TM is an easy statistical tool that can be used for optimization of pellet quality; using this method optimization is possible for each manufacture and helps the feed producers to achieve to the good pellet quality base on their specific conditions.

This method is a robust design approach and extensively applied for evaluation and optimization of products. Recent studies showed that this method has also been successfully applied to biotechnology (Khoudoli, Porter, Blow, & Swedlow, 2004Khoudoli, G. A., Porter, I. M., Blow, J. J., & Swedlow, J. R. (2004). Optimisation of the two-dimensional gel electrophoresis protocol using the Taguchi approach. Proteome Science 2. DOI: https://doi.org/10.1186/1477-5956-2-6
https://doi.org/https://doi.org/10.1186/...
; Lee, 2010Lee, D. S. (2010). Real-time PCR machine system modeling and a systematic approach for the robust design of a real-time PCR-on-a-chip system. Sensors, 10, 697-718. DOI: https://doi.org/10.3390/s100100697
https://doi.org/https://doi.org/10.3390/...
), agricultural sciences (Barghbani, Rezaei, & Javanshir, 2012Barghbani, R., Rezaei, K., & Javanshir, A. (2012). Investigating the effects of several parameters on the growth of Chlorella vulgaris using Taguchi’s experimental approach. International Journal of Biotechnology, 128-133 DOI: https://doi.org/10.6000/1927-3037/2012.01.02.04
https://doi.org/https://doi.org/10.6000/...
; Mahalakshmi & Ganesan, 2009Mahalakshmi, P., & Ganesan, K. (2009). Mahalanobis Taguchi System based criteria selection for shrimp aquaculture development. Computers and Electronics in Agriculture, 65(2), 192-197.; Moslemi & Khondabi, 2011Moslemi, A., & Khondabi, I. G. (2011). Using Experimental Designs in Order to Analyze the Effect of Effective Factors on Rice Seeds Weight. Australian Journal of Basic and Applied Sciences, 5(5), 334-340.) and cell culture ( Kallel et al., 2002Kallel, H., Zairi, H., Rourou, S., Essafi, M., Barbouche, R., Dellagi, K., & Fathallah, D. M. (2002). Use of Taguchi's methods as a basis to optimize hybridoma cell line growth and antibody production in a spinner flask. Cytotechnology, 39, 9-14. DOI: https://doi.org/10.1023/a:1022437514334
https://doi.org/https://doi.org/10.1023/...
).

Sedghi, Golian, Esmaeilipour, and Van Krimpen (2014Sedghi, M., Golian, A., Esmaeilipour, O., & Van Krimpen, M. M. (2014). Application of the Taguchi Method to Estimate the in Vitro Optimum Intrinsic Phytase Activity of Rye, Wheat and Barley. British Poultry Science, 55(2), 246-252.) evaluated the applicability of the TM to optimize in vitro intrinsic phytase activity (IPA) of rye, wheat and barley under different culture conditions. They also compared the results of the TM with those obtained by full factorial analysis. The comparison between the TM and full factorial results showed that the TM may be a sufficient and resource saving alternative to the full factorial design for optimization of several factors in poultry science.

The results of our study also showed that TM can be applied for optimization of pellet quality by testing multiple factors at the same time. This study serves as another example for the application of the Taguchi methodology for optimization of biological processes (Figure 4). This result would further facilitate to reduce the cost of the large scale experiments in poultry nutrition.

Figure 4
Interaction plots created by Taguchi method.

Conclusion

In Conclusion the major finding of this study was that the Taguchi method can be used to find the best combination of factors for optimal pellet quality by testing only a fraction of the treatments of the full factorial design.

Acknowledgements

The Authors declare the role of funding for research of Islamic Azad University, Kashmar Branch.The authors would like to thank the Zardaneh-Dizbad Feed mill Company staff for their contribution.

References

  • Abdollahi, M. R., Ravindran, V., Wester, T. J., Ravindran, G., & Thomas, D. V. (2011). Influence of feed form and conditioning temperature on performance, apparent metabolisable energy and ileal digestibility of starch and nitrogen in broiler starters fed wheat-based diet. Animal Feed Science and Technology, 168(1-2), 88-99. DOI: https://doi.org/10.1016/j.anifeedsci.2011.03.014
    » https://doi.org/https://doi.org/10.1016/j.anifeedsci.2011.03.014
  • Amerah, A. M., Ravindran, V., Lentle, R. G., & Thomas, D. G. (2007). Influence of feed particle size and feed form on the performance, energy utilization, digestive tract development, and digesta parameters of broiler starters. Poultry Science, 86, 2615-2623.
  • Antony, J. (2003). Design of experiments for engineers and scientists Oxford, EN: Elsevier Science and Technology Books.
  • Barghbani, R., Rezaei, K., & Javanshir, A. (2012). Investigating the effects of several parameters on the growth of Chlorella vulgaris using Taguchi’s experimental approach. International Journal of Biotechnology, 128-133 DOI: https://doi.org/10.6000/1927-3037/2012.01.02.04
    » https://doi.org/https://doi.org/10.6000/1927-3037/2012.01.02.04
  • Buchanan, N. P., & Moritz, J. S. (2009). Main effects and interactions of varying formulation protein, fiber, and moisture on feed manufacture and pellet quality. The Journal of Applied Poultry Research, 18, 274-283. DOI: https://doi.org/10.3382/japr.2008-00089
    » https://doi.org/https://doi.org/10.3382/japr.2008-00089
  • Buchanan, N. P., Lilly, K. G. S., & Moritz, J. S. (2010a). The effects of diet formulation, manufacturing technique, and antibiotic inclusion on broiler performance and intestinal morphology. The Journal of Applied Poultry Research, 19(2), 121-131. DOI: https://doi.org/10.3382/japr.2009-00071
    » https://doi.org/https://doi.org/10.3382/japr.2009-00071
  • Buchanan, N. P., Lilly, K. G. S., & Moritz, J. S. (2010b). The effects of altering diet formulation and manufacturing technique on pellet quality. The Journal of Applied Poultry Research, 19, 112-120. DOI: https://doi.org/10.3382/japr.2009-00070
    » https://doi.org/https://doi.org/10.3382/japr.2009-00070
  • Chung, C. C., Chen, H. H., & Hsieh, P. C. (2007). Application of Taguchi method to optimize monascus SPP. Culture Journal of Food Process Engineering, 30(2), 241-254. DOI: https://doi.org/10.1111/j.1745-4530.2007.00112.x
    » https://doi.org/https://doi.org/10.1111/j.1745-4530.2007.00112.x
  • Cutlip, S. E., Hott, J. M., Buchanan, N. P., Rack, A. L., Latshaw, J. D., & Moritz, J. S. (2008). The effect of steam conditioning practices on pellet quality and growing broiler nutritional value. The Journal of Applied Poultry Research, 17(2), 249-261. DOI: https://doi.org/10.3382/japr.2007-00081
    » https://doi.org/https://doi.org/10.3382/japr.2007-00081
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    » https://doi.org/https://doi.org/10.3382/ps/peu070
  • Itani, K., & Svihus, B. (2019). Feed processing and structural components affect starch digestion dynamics in broiler chickens.British Poultry Science, 60(3), 246-255. DOI: https://doi.org/10.1080/00071668.2018.1556388
    » https://doi.org/https://doi.org/10.1080/00071668.2018.1556388
  • Kallel, H., Zairi, H., Rourou, S., Essafi, M., Barbouche, R., Dellagi, K., & Fathallah, D. M. (2002). Use of Taguchi's methods as a basis to optimize hybridoma cell line growth and antibody production in a spinner flask. Cytotechnology, 39, 9-14. DOI: https://doi.org/10.1023/a:1022437514334
    » https://doi.org/https://doi.org/10.1023/a:1022437514334
  • Kiarie, E. G., & Mills, A. (2019). Role of feed processing on gut health and function in pigs and poultry: conundrum of optimal particle size and hydrothermal regimens.Frontiers in Veterinary Science, 6, 19. DOI: https://doi.org/10.3389/fvets.2019.00019
    » https://doi.org/https://doi.org/10.3389/fvets.2019.00019
  • Khoshbin, M. R., Vakili, R., & Tahmasbi, A. M. (2023). Manganese-methionine chelate improves antioxidant activity, immune system and egg manganese enrichment in the aged laying hens. Veterinary Medicine and Science, 9(1), 217-225. DOI: https://doi.org/10.1002/vms3.1008
    » https://doi.org/https://doi.org/10.1002/vms3.1008
  • Khoudoli, G. A., Porter, I. M., Blow, J. J., & Swedlow, J. R. (2004). Optimisation of the two-dimensional gel electrophoresis protocol using the Taguchi approach. Proteome Science 2 DOI: https://doi.org/10.1186/1477-5956-2-6
    » https://doi.org/https://doi.org/10.1186/1477-5956-2-6
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Publication Dates

  • Publication in this collection
    09 Oct 2023
  • Date of issue
    2023

History

  • Received
    28 Apr 2021
  • Accepted
    22 Sept 2022
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