ABSTRACT
Background:
Inflammatory bowel disease (IBD) is a lifestyle idiopathic, chronic, and inflammatory intestinal disorders that required long-term medications and care.
Aim of the study:
Assess the level of adiponectin in IBDU and its relation with different parameters like lipid profile and Body Mass Index (BMI).
Type of the study:
A case-controlled study.
Patients and methods:
The total number of study groups was sixty individuals, forty of them were patients with inflammatory bowel disease unclassified and the rest were control healthy subjects. Serums were examined for lipid profile (cholesterol, triglyceride, HDLP, LDLP (Human-Germany), adiponectin (Human-Germany).
Results:
Adiponectin, cholesterol, triglyceride, LDL and LDL/HDL were significantly higher in patient group. The results showed that there was a negative correlation between adiponectin and height (r = -0.071), waist to hip ratio (r = -0.174), cholesterol (r = -0.417), HDL (r = -0.039), LDL (r = -0.451) while other parameters there are positive correlation.
Conclusions:
IBDU is associated with increased level of adiponectin which is positively associated with BMI and triglyceride. It is negatively correlation with height, waist to hip ratio, cholesterol, HDL and LDL.
Keywords:
Adiponectin; Colitis; BMI