The descendants of planorbid snail Biomphalaria schrammi Crosse, 1864, collected in the region of Arcos, State of Minas Gerais, Brazil, were exposed to miracidia of two strains of Schistosoma mansoni: the "LE" strain from Belo Horizonte, Minas Gerais State and the "SJ" strain from São José dos Campos, State of São Paulo. Of the 172 snails exposed to miracidia of both strains, none were infected. On the other hand, 100 Biomphalaria glabrata snails of the control group showed infection rates of 88% ("LE" strain) and 40% ("SJ" strain). The mortality rates of B. schrammi and B. glabrata were 40% and 10%, respectively.