Despite its reputation for openness to research on sexuality, anthropology as a discipline has only reluctantly supported such work. Anthropological research and theory developed slowly, sharing a stable theoretical paradigm (the cultural influence model) from the 1920s to the 19908. Moving beyond determinist and essentialist frameworks still common in biomedicine, anthropological work nevertheless viewed important aspects of sexuality as universal and transcultural. Social construction theory has offered a challenge to tradit.ional anthropological models and has been responsible for a recent burst of innovative work in sexuality, both in anthropology and in other disciplines, since 1975. The theoretical roots and implications of constructionist theory are explored. The intensifymg competition between cultural influence and constructionist paradigms has been altered by the appearance of AIDS and the subsequent increased support to: research on sexuality. On the one hand, the expansion in funding threatens to strengthen essentialist models in biomedical contexts and cultural influence models in anthropology. On the other hand, the complexities and ambiguities inherent in the sexuality under study may both reveal the strengths of constructioriist approaches and spur the development of research and theory in anthropology.