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Antimicrobial activity of Mimosa tenuiflora (Willd.) Poir. from Northeast Brazil against clinical isolates of Staphylococcus aureus

Atividade antimicrobiana de Mimosa tenuiflora (Willd.) Poir. do Nordeste do Brasil, contra isolados clínicos de Staphylococcus aureus

Mimosa tenuiflora is a native plant of Northeast Brazil where it is popularly known as ''jurema-preta'' and it is widely used in folk medicine. In this work the anti-Staphylococcus aureus activity of ethanol extract of M tenuiflora was evaluated by determination of minimum inhibitory concentration (MIC) of clinical isolates by the agar dilution method, and by time-kill assay using a reference strain. MIC values against 30 isolates were 0,18 mg/mL (16/30) or 0,36 mg/mL (14/30, and also the reference strain). In the reference strains, at concentrations up to 4x MIC, only bacteriostatic effect was observed, but at 8x MIC a fast bactericidal effect was observed.

Mimosa tenuiflora; ethanol extract; antimicrobial activity; Staphylococcus aureus


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