Acessibilidade / Reportar erro

Death due to Allopurinol Hypersensivity Syndrome (AHS)

Hyperuricemia can lead to deposition of monosodium urate crystals in the joint cavity or to "physicians' anguish", causing prescription of unnecessary drugs. In this case, more side effects than benefits will be observed. Allopurinol is the most prescribed urate lowering drug and hypersensivity reactions occur in up to 10% of patients taking the drug, with mortality of 20%. With this case report we intend to characterize the Allopurinol Hypersensivity Syndrome (AHS), emphasizing the right use of the drug.

Allopurinol Hypersensivity Syndrome (AHS); hyperuricemia; side effect


Sociedade Brasileira de Reumatologia Av Brigadeiro Luiz Antonio, 2466 - Cj 93., 01402-000 São Paulo - SP, Tel./Fax: 55 11 3289 7165 - São Paulo - SP - Brazil
E-mail: sbre@terra.com.br