Aspecto citológico de tumores intracranianos e do canal vertebral

Campos, Ivelise de Souza; Chimelli, Leila

doi:10.1590/S0004-282X1993000200008

Resumos

Apresentamos os aspectos citológicos de 137 lesões tumorals operadas por neurocirurgiões, incluindo 12 astrocitomas, 4 astrocitomas anaplásicos, 20 glioblastomas, 7 oligodendrogliomas, 7 ependimomas, 5 meduloblastomas, 8 schwannomas, 7 meningiomas, 13 adenomas de hipófise, 20 tumores metastáticos e 18 tumores diversos e patologias não neoplasias. Analisamos também citologicamente amostras de tecido nervoso normal obtido de necrópsias, com o objetivo de reconhecê-lo nas biópsias e distingui-lo do tecido neoplásico. Toüo o material foi analisado por esfregaços, que foram comparados posteriormente com os cortes histológicos. Apesar da necessidade de observar os detalhes celulares dos tumores, muitas vezes o arranjo peculiar das células em uma visão de conjunto praticamente permite o diagnóstico da neoplasia no esfregaço.

tumores intracranianos; tumores do canal vertebral; aspectos citológicos

We present the cytologic aspects of 137 tumors operated by neurosurgeons, including 12 astrocytomas, 4 anaplastic astrocytomas, 26 glioblastomas, 7 oligodendrogliomas, 5 meduloblastomas, 8 schwannomas, 17 meningiomas, 13 pituitary adenomas, 20 metastatic tumors and 18 assorted tumors and nonneoplastic lesions. We have also analysed cytologically samples of normal nervous tissue obtained from autopsies, aiming at its recognition and distinction from the neoplastic tissue in biopsies. The tumors were analysed in smears which were subsequently compared with the histological sections. Although it is important to observe cytological details in the tumor, occasionally cells are arranged in such a way, that an overview of the smear pratically allows the diagnosis of the tumor.

intracranial tumors; spinal tumors; cytologic aspects

Ivelise de Souza Campos; Leila Chimelli

Departamento de Patologia, Hospital Universitário Antônio Pedro, Universidade Federal Fluminense (UFF), Niterói

RESUMO

Apresentamos os aspectos citológicos de 137 lesões tumorals operadas por neurocirurgiões, incluindo 12 astrocitomas, 4 astrocitomas anaplásicos, 20 glioblastomas, 7 oligodendrogliomas, 7 ependimomas, 5 meduloblastomas, 8 schwannomas, 7 meningiomas, 13 adenomas de hipófise, 20 tumores metastáticos e 18 tumores diversos e patologias não neoplasias. Analisamos também citologicamente amostras de tecido nervoso normal obtido de necrópsias, com o objetivo de reconhecê-lo nas biópsias e distingui-lo do tecido neoplásico. Toüo o material foi analisado por esfregaços, que foram comparados posteriormente com os cortes histológicos. Apesar da necessidade de observar os detalhes celulares dos tumores, muitas vezes o arranjo peculiar das células em uma visão de conjunto praticamente permite o diagnóstico da neoplasia no esfregaço.

Palavras-chave: tumores intracranianos, tumores do canal vertebral, aspectos citológicos.

SUMMARY

We present the cytologic aspects of 137 tumors operated by neurosurgeons, including 12 astrocytomas, 4 anaplastic astrocytomas, 26 glioblastomas, 7 oligodendrogliomas, 5 meduloblastomas, 8 schwannomas, 17 meningiomas, 13 pituitary adenomas, 20 metastatic tumors and 18 assorted tumors and nonneoplastic lesions. We have also analysed cytologically samples of normal nervous tissue obtained from autopsies, aiming at its recognition and distinction from the neoplastic tissue in biopsies. The tumors were analysed in smears which were subsequently compared with the histological sections. Although it is important to observe cytological details in the tumor, occasionally cells are arranged in such a way, that an overview of the smear pratically allows the diagnosis of the tumor.

Key words: intracranial tumors, spinal tumors, cytologic aspects.

Full text available only in PDF format.

Texto completo disponível apenas em PDF.

Aceite: 22-agosto-1992.

Dra. Leila Chimelli Departamento de Patologia, Hospital Universitário Antônio Pedro Rua Marquês do Paraná 303 24030 Niterói RJ Brasil.

1. Adams JH, Graham DI, Doyle D. Brain biopsy: the smear techniques for neurosurgical biopsies. London: Chapman and Hall, 1981.
2. Balhuizen JC, Bots GTAM, Schaberg A, The value of cytology in the diagnosis of hypophyseal tumors. Acta Cytol 1974, 18:370-375.
3. Cahill EM, Hidvegi DF. Crush preparations of lesions of the central nervous system: a useful adjunct to the frozen section. Acta Cytol 1985, 29:279-285.
4. Colins VP. Monoclonal antibodies to glial fibrillary acidic protein in the cytologic diagnosis of brain tumors. Acta Cytol 1984, 28:401-406.
5. Colombo F, Casentini L, Visona A, Benedetti A. Stereotactic biopsy diagnostic problems: value of cytological and histological examinations. Zbl Neurochir 1982, 43:309-313.
6. Crain BJ, Bigner SIL Johnston WW. Fine needle aspiration biopsy of deep cerebrum: a comparison of normal and neoplastic morphology. Acta Cytol 1982, 26:772-778.
7. Earnest F, Kelly PJ, Scheithauer BW, Kali BA, Cascino TL, Ehman RL, Forbes GS, Axley PL. Cerebral astrocytomas: histopathologic correlation of MR and CT contrast enhancement with stereotactic biopsy. Radiology 1988, 166:823-827.
8. Enriquez R, Egbert B, Bullock J, Haven W. Primary malignant melanoma of central nervous system. Arch Pathol 1973, 95:392-395.
9. Gandolfi A. The cytology of cerebral neuroblastoma. Acta Cytol 1980, 24:344-346.
10. González-Cámpora R, Haynes LW, Wellek RO. Scanning electron microscopy of malignant gliomas: a comparative study of glioma cells in smear preparations and in tissue culture. Acta Neuropathol 1978, 41:217-221.
11. Jane JA, Bertrand G. A cytological method for the diagnosis of tumors affecting the central nervous system. J Neuropathol Exp Neurol 1962, 21:400-409.
12. Lever WF, Schawmburg-Lever G. Nevos melanocítico y melanoma maligno. In Lever WF, Schawmburg-Lever G: Histopatologia de la piel. Ed 5. Buenos Aires: Intermedica, 1979, p 571-602.
13. Liwnicz BH, Henderson KS, Mazukawa T, Smith RD. Needle aspiration cytology of intracranial lesions: a review of 84 cases. Acta Cytol 1982, 26:779-786.
14. Marshall LF, Adams H, Doyle D, Graham DI. The histological accuracy of the smear technique for neurosurgical biopsies. J Neurosurg 1973, 39:82-88.
15. McMenemey WH. An appraisal of smear-diagnosis in neurosurgery. AM J Clin Pathol 1960, 33:471-479.
16. Mouriquand C, Benabid AL, Breyton M. Stereotaxic cytology of brain tumors: review of tan eight-year experience. Acta Cytol 1987, 31:756-764.
17. Nelson JS, Tsukada Y, Schoenfeld D, Fulling K, Lamarche J, Peress N. Necrosis as a prognostic criterion in malignant supratentorial, astrocytic gliomas. Cancer 1983, 52:550-554.
18. Ostertag CB, Mennel HD, Kiessling M. Stereotactic biopsy of brain tumors. Surg Neurol 1980, 14:275-283.
19. Papo I, Beduschi A, D'Andrea F. II método per schiacciamento e striscio nella diagnosi peroperatoria dei tumori endocranici. Acta Neurol (Napoli) 1S56, 11:1182-1194.
20. Papo I, Colombo F. Possibilità e limite dell'esame estemporaneo per shiacciamento e striscio nella diagnosi peroperatoria dei tumori endocranici. Minerva Neurochir 1959, 3:134-147.
21. Petito GK, DeGirolami U, Earle KM. Craniofaryngiomas: a clinical and pathological review. Cancer 1976, 37:1944-1952.
22. Russell DS, Rubinstein LJ. Pathology of tumours of the nervous system. Ed 5. Baltimore: Williams & Wilkins, 1989, p 871-875.
23. Takahashi M. Citologia prática dos órgãos: sistema nervoso central. In Takahashi M: Atlas colorido de citologia do câncer. Ed 2. São Paulo: Manóle, 1982, p 386-408.
24. Taratuto AL, Sevlever G, Piccardo P. Clues and pitfalls in stereotactic biopsy of the central nervous system. Arch Path Lab Med 1991, 115:596-602.
25. Torres LFB, Collaço LM. Diagnóstico citopatológico de tumores neuroepiteliais pela técnica do esfregaço. Arq Neuro-Psiquiat (São Paulo) 1992, 50:173-179.
26. Watson CW, Hadju SI. Cytology of primary neoplasms of the central nervous system. Acta Cytol 1977, 21:40-47.
27. Willems JC, Alva-Willems JM. Accuracy of cytologic diagnosis of central nervous system neoplasms in stereotactic biopsies. Acta Cytol 1984, 28:243-249.
28. Yashon D, Jane JA. Central nervous system tissue cyto'logy. Progr Exp Tumor Res 1972, 17:346-362.
29. Zaharapoulos P, Wong JY. Cytology of common primary midline brain tumors. Acta Cytol 1980, 24:384-390.

Aspecto citológico de tumores intracranianos e do canal vertebral

Cytologic aspects of intracranial and spinal tumors

Datas de Publicação

Publicação nesta coleção
19 Jan 2011
Data do Fascículo
Jun 1993

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

[1] 1. Adams JH, Graham DI, Doyle D. Brain biopsy: the smear techniques for neurosurgical biopsies. London: Chapman and Hall, 1981.

[2] 2. Balhuizen JC, Bots GTAM, Schaberg A, The value of cytology in the diagnosis of hypophyseal tumors. Acta Cytol 1974, 18:370-375.

[3] 3. Cahill EM, Hidvegi DF. Crush preparations of lesions of the central nervous system: a useful adjunct to the frozen section. Acta Cytol 1985, 29:279-285.

[4] 4. Colins VP. Monoclonal antibodies to glial fibrillary acidic protein in the cytologic diagnosis of brain tumors. Acta Cytol 1984, 28:401-406.

[5] 5. Colombo F, Casentini L, Visona A, Benedetti A. Stereotactic biopsy diagnostic problems: value of cytological and histological examinations. Zbl Neurochir 1982, 43:309-313.

[6] 6. Crain BJ, Bigner SIL Johnston WW. Fine needle aspiration biopsy of deep cerebrum: a comparison of normal and neoplastic morphology. Acta Cytol 1982, 26:772-778.

[7] 7. Earnest F, Kelly PJ, Scheithauer BW, Kali BA, Cascino TL, Ehman RL, Forbes GS, Axley PL. Cerebral astrocytomas: histopathologic correlation of MR and CT contrast enhancement with stereotactic biopsy. Radiology 1988, 166:823-827.

[8] 8. Enriquez R, Egbert B, Bullock J, Haven W. Primary malignant melanoma of central nervous system. Arch Pathol 1973, 95:392-395.

[9] 9. Gandolfi A. The cytology of cerebral neuroblastoma. Acta Cytol 1980, 24:344-346.

[10] 10. González-Cámpora R, Haynes LW, Wellek RO. Scanning electron microscopy of malignant gliomas: a comparative study of glioma cells in smear preparations and in tissue culture. Acta Neuropathol 1978, 41:217-221.

[11] 11. Jane JA, Bertrand G. A cytological method for the diagnosis of tumors affecting the central nervous system. J Neuropathol Exp Neurol 1962, 21:400-409.

[12] 12. Lever WF, Schawmburg-Lever G. Nevos melanocítico y melanoma maligno. In Lever WF, Schawmburg-Lever G: Histopatologia de la piel. Ed 5. Buenos Aires: Intermedica, 1979, p 571-602.

[13] 13. Liwnicz BH, Henderson KS, Mazukawa T, Smith RD. Needle aspiration cytology of intracranial lesions: a review of 84 cases. Acta Cytol 1982, 26:779-786.

[14] 14. Marshall LF, Adams H, Doyle D, Graham DI. The histological accuracy of the smear technique for neurosurgical biopsies. J Neurosurg 1973, 39:82-88.

[15] 15. McMenemey WH. An appraisal of smear-diagnosis in neurosurgery. AM J Clin Pathol 1960, 33:471-479.

[16] 16. Mouriquand C, Benabid AL, Breyton M. Stereotaxic cytology of brain tumors: review of tan eight-year experience. Acta Cytol 1987, 31:756-764.

[17] 17. Nelson JS, Tsukada Y, Schoenfeld D, Fulling K, Lamarche J, Peress N. Necrosis as a prognostic criterion in malignant supratentorial, astrocytic gliomas. Cancer 1983, 52:550-554.

[18] 18. Ostertag CB, Mennel HD, Kiessling M. Stereotactic biopsy of brain tumors. Surg Neurol 1980, 14:275-283.

[19] 19. Papo I, Beduschi A, D'Andrea F. II método per schiacciamento e striscio nella diagnosi peroperatoria dei tumori endocranici. Acta Neurol (Napoli) 1S56, 11:1182-1194.

[20] 20. Papo I, Colombo F. Possibilità e limite dell'esame estemporaneo per shiacciamento e striscio nella diagnosi peroperatoria dei tumori endocranici. Minerva Neurochir 1959, 3:134-147.

[21] 21. Petito GK, DeGirolami U, Earle KM. Craniofaryngiomas: a clinical and pathological review. Cancer 1976, 37:1944-1952.

[22] 22. Russell DS, Rubinstein LJ. Pathology of tumours of the nervous system. Ed 5. Baltimore: Williams & Wilkins, 1989, p 871-875.

[23] 23. Takahashi M. Citologia prática dos órgãos: sistema nervoso central. In Takahashi M: Atlas colorido de citologia do câncer. Ed 2. São Paulo: Manóle, 1982, p 386-408.

[24] 24. Taratuto AL, Sevlever G, Piccardo P. Clues and pitfalls in stereotactic biopsy of the central nervous system. Arch Path Lab Med 1991, 115:596-602.

[25] 25. Torres LFB, Collaço LM. Diagnóstico citopatológico de tumores neuroepiteliais pela técnica do esfregaço. Arq Neuro-Psiquiat (São Paulo) 1992, 50:173-179.

[26] 26. Watson CW, Hadju SI. Cytology of primary neoplasms of the central nervous system. Acta Cytol 1977, 21:40-47.

[27] 27. Willems JC, Alva-Willems JM. Accuracy of cytologic diagnosis of central nervous system neoplasms in stereotactic biopsies. Acta Cytol 1984, 28:243-249.

[28] 28. Yashon D, Jane JA. Central nervous system tissue cyto'logy. Progr Exp Tumor Res 1972, 17:346-362.

[29] 29. Zaharapoulos P, Wong JY. Cytology of common primary midline brain tumors. Acta Cytol 1980, 24:384-390.