1 |
Limb weakness, hypoesthesia, neurogenic bladder |
Cardiac disease, thrombotic events, seizure, sudden bilateral painfull amaurosis, aggression outbreaks, early cognitive decline with dysarthria. |
Multiple cerebral emboli due to atrial mixoma |
1.0 |
NA |
Atrial mixoma Branch retinal artery occlusion on ophthalmologic evaluation Normal brain biopsy |
- |
+ |
- |
+ |
- |
Absence of temporal horn lesion, infratentorial and spinal cord lesion. Most lesions are sucortical |
2 |
Limb weakness, paresthesia, urge incontinence, spasticity |
Myalgias, anxiety, somnolence, abrupt onset, onset after age 50 |
Yellow fever vaccine associated encephalitis |
1.0 |
NA |
Brain biopsy with atypical inflammatory infiltrate and white matter with gliosis |
- |
+ |
- |
+ |
- |
Absence of temporal horn lesion, infratentorial and spinal cord lesion. Most lesions are large and subcortical, all enhance at the same time |
3 |
Limb weakness, paresthesia, sensory ataxia |
Normal neurological evaluation |
Syringomyelia |
1.2 |
NA |
Normal visual evoked potentials |
- |
+ |
- |
+ |
- |
Lesion compatible with syringomielia. No lesions on brain MRI. |
4 |
Limb weakness, paresthesia, diplopia, hypoesthesia |
Seizure, Headache, mucosal ulcers, aggression, early dysarthria and dysphagia |
NeuroBehçet |
Up to 250.0 cell/mm3with neutrophil predominance |
NA |
CSF pleocytosis |
- |
+ |
+ |
+ |
+ |
Absence of spinal cord lesion. Most lesions are large and subcortical or large and in the brainstem |
5 |
Limb weakness, fatigue, gait ataxia, sensory loss, spasticity |
Extrapyramidal features, retinopathy, early and severe dysarthria, early cognitive impairment and abrupt onset |
Susac syndrome or Primary CNS vasculitis |
13.0 |
Presence |
Rethynopathy Brain biopsy with necrotizing vasculitis |
- |
+ |
+ |
+ |
+ |
Absence of temporal horn lesion and infratentorial lesion. Most lesions are large and subcortical. |
6 |
Limb weakness, pain, spasticity |
Polyradiculopathy, myopathy and muscle pain, amyotrophy, past medical history of gastric bypass surgery |
Polyneuromyopathy and myelopathy due to severe nutritional deficiency |
2.0 |
NA |
Anemia, low serum vitamin D, iron, copper and zinc |
+ |
+ |
- |
+ |
+ |
No |
7 |
Gait ataxia, spasticity, sensory loss, tetraparesis, urinary incontinence |
Retinopathy, hearing loss, cutaneous involvement, early severe cognitive impairment and dysarthira |
Susac syndrome |
2.0 |
Absence |
Skin biopsy with leukocytoclastic vasculitis, hearing loss on audiologic evaluation, elevated CSF protein (114mg/dL) |
- |
- |
- |
- |
- |
Punctiform lesions, diffusion restriction and lesions restricted to the corpos callosum (snowball lesions) |
8 |
Hemiparesis, sensory loss, spasticity |
Headache, seizure, thrombotic events, progressive severe early hemiparesis |
Primary CNS lymphoma (under review) |
9.0 |
NA |
Brain biopsy not typical of MS with atypical lymphocytic infiltrate |
- |
- |
- |
- |
- |
Exclusively unilateral hemispheric lesion |
9 |
Depression, vertigo |
Headache, hearing loss, bilateral ptosis |
Mithocondrial disorder (under review) |
1.0 |
NA |
|
- |
- |
- |
+ |
- |
Absence of temporal horn lesion, infratentorial and spinal cord lesion. Most lesions are small, round and scarce in the subcortical white matter |