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Revista Brasileira de Ginecologia e Obstetrícia

Print version ISSN 0100-7203On-line version ISSN 1806-9339


AZEVEDO, Patrícia de Fátima et al. Congenital cytomegalovirus infection: a case report. Rev. Bras. Ginecol. Obstet. [online]. 2005, vol.27, n.12, pp.750-758. ISSN 1806-9339.

Congenital cytomegalovirus infection is an important clinical entity, due to its sonographic symptomatology. In Brazil, in utero diagnosis is not accomplished despite the improvements in diagnostic methods. We report a congenital infection including: splenomegaly and hepatomegaly, hypoplasia of the cerebellar vermis, intracranial calcifications, hyperechoic kidneys, hyperechoic bowel, cardiomegaly, lung hypoplasia, ascites, and pericardial effusion. Fetal magnetic resonance imaging confirmed the sonographic findings. Amniocentesis was performed for cytomegalovirus PCR in amniotic fluid, which confirmed fetal infection. Fetal loss occurred in the 31st week of pregnancy. Necropsy studies confirmed the sonographic findings. The diagnostic methods have been useful to confirm congenital cytomegalovirus infection and to establish fetal outcome.

Keywords : Cytomegalovirus; Cytomegalovirus infections [congenital]; Prenatal diagnosis; Ultrasonography [prenatal]; Magnetic resonance Imaging.

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