Brazilian Dental Journal
On-line version ISSN 1806-4760
FARACO, Fatima Neves; ARMONIA, Paschoal Laércio; SIMONE, José Leonardo and TORTAMANO, Nicolau. Assessment of cardiovascular parameters during dental procedures under the effect of benzodiazepines: a double blind study. Braz. Dent. J. [online]. 2003, vol.14, n.3, pp. 215-219. ISSN 1806-4760. http://dx.doi.org/10.1590/S0103-64402003000300014.
The purpose of this study was to evaluate cardiovascular parameters during dental procedures: systolic, diastolic, and mean blood pressures, and heart rate. Nineteen healthy normotensive patients (18-56 years of age) received restorative treatment on three maxillary molars. The patients were continuously monitored by a non-invasive automatic monitor for blood pressure and heart rate during the pre-, trans-, and post-operative periods at the following stages: 15 min prior to anesthesia; during topical anesthesia; during infiltrative anesthesia; for 5 minutes immediately after; during cavity preparation; during restorative procedure; for 10 min after completion. Patients were divided into three groups: A (without pre-medication), B (preceded by 10 mg diazepam), and C (preceded by placebo). All patients received infiltrative anesthesia containing 1.8 mL of 2% lidocaine (36 mg) with epinephrine 1:100,000 (18 µg). There were no changes in the parameters during the clinical procedures. When groups were compared, there were significant differences in diastolic arterial pressures during anesthesia.
Keywords : cardiovascular alterations; lidocaine; benzodiazepines; epinephrine.