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Revista Latino-Americana de Enfermagem

On-line version ISSN 1518-8345


CARDOSO, Maria Vera Lúcia Moreira Leitão; FARIAS, Leiliane Martins  and  MELO, Gleicia Martins de. Music and 25% glucose pain relief for the premature infant: a randomized clinical trial. Rev. Latino-Am. Enfermagem [online]. 2014, vol.22, n.5, pp.810-818. ISSN 1518-8345.


to analyze the total Premature Infant Pain Profile scores of premature infants undergoing arterial puncture during music and 25% glucose interventions, and to assess their association with neonatal and therapeutic variables.


a randomized clinical trial with 80 premature infants; 24 in the Experimental Group 1 (music), 33 in the Experimental Group 2 (music and 25% glucose), 23 in the Positive Control Group (25% glucose). All premature infants were videotaped and a lullaby was played for ten minutes before puncture in Experimental Groups 1 and 2; 25% glucose administered in Experimental Group 2 and the Positive Control Group two minutes before puncture.


60.0% of premature infants had moderate or maximum pain; pain scores and intervention groups were not statistically significant. Statistically significant variables: Experimental Group 1: head and chest circumference, Apgar scores, corrected gestational age; Experimental Group 2: chest circumference, Apgar scores, oxygen therapy; Positive Control group: birth weight, head circumference.


neonatal variables are associated with pain in premature infants. Brazilian Registry of Clinical Trials: UTN: U1111-1123-4821.

Keywords : Infant; Neonatal Nursing; Randomized Controlled Trial; Pain.

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