História, Ciências, Saúde-Manguinhos
Print version ISSN 0104-5970
MARTINS, Lilian Al-Chueyr Pereira. McClung and gender determination: from wrong to right. Hist. cienc. saude-Manguinhos [online]. 1999, vol.6, n.2, pp. 235-256. ISSN 0104-5970. http://dx.doi.org/10.1590/S0104-59701999000300001.
Focusing primarily on McClungs hypothesis linking the extra chromosome (X) to gender determination, the article studies some contributions derived from the initial stages in development of the chromosome theory of gender determination. The arguments of McClung and others are analyzed, along with the reaction of the eras scientific community. Although McClungs hypothesis was wrong, it triggered a series of research studies that eventually led to clarification of the question. Even mistaken hypotheses, when adopted for investigation and testing, can contribute to scientific development.
Keywords : extra chromosome; gender determination; Clarence Erwin McClung; hypothesis.