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LETTER TO THE EDITOR • An. Acad. Bras. Ciênc. 92 (4) • 2020 • https://doi.org/10.1590/0001-3765202020201080 linkcopy

Open-access Cardiac glycosides and COVID-19: would it be a promising therapeutic approach?

AuthorshipSCIMAGO INSTITUTIONS RANKINGS

Cardiac glycosides have been found to have an anti-viral effect. This was noted in the past during various epidemics including MERS and SARS. It is due to their inhibitory effect on the Na, K-ATPase membrane pump. Furthermore, they exhibit anti-inflammatory properties. These preclinical observations may prove useful in further clinical utility of these well-known compounds in the current COVID-19 pandemic.

Key words
antiviral effect; cardiac glycosides; COVID-19

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