Cutaneous mucinosis in mixed connective tissue disease * Study conducted at the Rheumatology and Dermatology Department of the Hospital das Clínicas of the Faculty of Medicine, University of São Paulo (HC-FMUSP) - São Paulo (SP), Brazil. *

Mucinose cutânea na doença mista do tecido conjuntivo

Maria Helena Sampaio Favarato Sofia Silveira de Castro Miranda Maria Teresa Correia Caleiro Ana Paula Luppino Assad Ilana Halpern Ricardo Fuller About the authors

Cutaneous mucinosis is a group of conditions involving an accumulation of mucin or glycosaminoglycan in the skin and its annexes. It is described in some connective tissue diseases but never in association with mixed connective tissue disease. This report concerns two cases of cutaneous mucinosis in patients with mixed connective tissue disease in remission; one patient presented the papular form, and the other reticular erythematous mucinosis. These are the first cases of mucinosis described in mixed connective tissue disease. Both cases had skin lesions with no other clinical or laboratorial manifestations, with clinical response to azathioprine in one, and to an association of chloroquine and prednisone in the other.

Autoimmune diseases; Lupus erythematosus, cutaneous; Mixed connective tissue disease; Mucinoses


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