Purpose: To evaluate the effectiveness and the complications on intraoperative application of 5-fluorouracil (5FLU) in pterygium surgery. Method: We studied 28 eyes of 26 patients with pterygium, evaluating the type and size of the pterygium, previous surgeries and the response to surgical treatment (on the 7th, 21st, 60th, 90th postoperative day). The application of 5-FLU (25 mg/ml) was done soon after resection, for five minutes, followed by the sliding flap technique.Results: Most of the patients were more than 50 years old, presented with primary (70.0%), degree II (60.7%), involu-tionary type (60.7%) pterygium. After surgery ischemic area (10.7%), conjunctival deiscence (7.1%), keratitis (3.5%), conjunctivitis (3.5%) and lesion relapse (3.5%) were observed.Conclusion: 5-FLU is a safe and effective drug and could be of help in the treatment of pterygium to prevent relapse.
Pterygium; 5-fluorouracil; Antimitotic; Relapse
