Abreu R et al. (22 Abreu R, Miguel R, Saieg M. Subacute (De Quervain) thyroiditis during the COVID-19 pandemic. Cancer Cytopathol. 2021 May 10. doi:10.1002/cncy.22449. https://doi.org/10.1002/cncy.22449...
) |
Brazil |
F, 34 y |
28 |
N.A. |
N.A. |
Prednisone 15 mg/d |
Abreu R et al. (22 Abreu R, Miguel R, Saieg M. Subacute (De Quervain) thyroiditis during the COVID-19 pandemic. Cancer Cytopathol. 2021 May 10. doi:10.1002/cncy.22449. https://doi.org/10.1002/cncy.22449...
) |
Brazil |
F, 34 y |
10 |
FT4 1.8 ng/dL |
N.A. |
Prednisone |
Abreu R et al. (22 Abreu R, Miguel R, Saieg M. Subacute (De Quervain) thyroiditis during the COVID-19 pandemic. Cancer Cytopathol. 2021 May 10. doi:10.1002/cncy.22449. https://doi.org/10.1002/cncy.22449...
) |
Brazil |
F, 39 y |
26 |
N.A. |
N.A. |
N.A. |
Álvarez Martín MC et al. (33 Álvarez Martín MC, Del Peso Gilsanz C, Hernández López A. Subacute De Quervain thyroiditis after SARS-CoV-2 infection. Endocrinol Diabetes Nutr (Engl Ed). 2020;68(10):754.) |
Spain |
F, 46 y |
Asymptomatic COVID-19, during SAT, SARS-CoV-2 serology positive |
TSH 0.11 mIU/mL FT4 2.18 ng/dL ESR 68 mm/h |
TSH 0.55-4.78 mIU/mL FT4 0.89-1.76 ng/dL |
Prednisone 40 mg/d |
Asfuroglu Kalkan E et al. (44 Asfuroglu Kalkan E, Ates I. A case of subacute thyroiditis associated with Covid-19 infection. J Endocrinol Invest. 2020;43(8):1173-4.) |
Turkey |
F, 41 y |
Asymptomatic COVID-19, during SAT, SARS-CoV-2 PCR positive |
TSH < 0.008 mIU/L FT4 25.7 pmol/L FT3 7.7 pmol/L CRP 101 mg/L ESR 134 mm/h |
TSH < 0.008 mIU/L FT4 12-21 pmol/L FT3 3.1-6.8 pmol/L |
Hydroxychloroquine 200 mg/d Prednisone 16 mg/d |
Brancatella A et al. (11 Brancatella A, Ricci D, Viola N, Sgrò D, Santini F, Latrofa F. Subacute thyroiditis after Sars-COV-2 infection. J Clin Endocrinol Metab. 2020;105(7):dgaa276.) |
Italy |
F, 18 y |
19 |
TSH < 0.04 mIU/L FT4 27.2 nmol/L FT3 8.7 pmol/L CRP 6.9 mg/L ESR 90 mm/h |
TSH 0.5-4.1 mIU/L FT4 11-23 nmol/L FT3 4.6-8.4 pmol/L |
Prednisone 25 mg/d |
Brancatella A et al. (55 Brancatella A, Ricci D, Cappellani D, Viola N, Sgrò D, Santini F, et al. Is subacute thyroiditis an underestimated manifestation of SARS-CoV-2 infection? Insights from a case series. J Clin Endocrinol Metab. 2020;105(10):dgaa537.) |
Italy |
F, 38 y |
16 |
TSH 0.1 mIU/mL FT4 29.3 nmol/L FT3 8.0 pmol/L CRP 11.2 mg/L ESR 74 mm/h |
TSH 0.4-4.5 mIU/mL FT4 6-16 nmol/L FT3 2.3-4.2 pmol/L |
Prednisone 25 mg/d |
Brancatella A et al. (55 Brancatella A, Ricci D, Cappellani D, Viola N, Sgrò D, Santini F, et al. Is subacute thyroiditis an underestimated manifestation of SARS-CoV-2 infection? Insights from a case series. J Clin Endocrinol Metab. 2020;105(10):dgaa537.) |
Italy |
F, 29 y |
30 |
TSH < 0.01 mIU/mL FT4 31.8 nmol/L FT3 8.9 pmol/L CRP 7.9 mg/L ESR 110 mm/h |
TSH 0.4-4.5 mIU/mL FT4 6-16 nmol/L FT3 2.3-4.2 pmol/L |
Prednisone 25 mg/d propranolol 40 mg/d |
Brancatella A et al. (55 Brancatella A, Ricci D, Cappellani D, Viola N, Sgrò D, Santini F, et al. Is subacute thyroiditis an underestimated manifestation of SARS-CoV-2 infection? Insights from a case series. J Clin Endocrinol Metab. 2020;105(10):dgaa537.) |
Italy |
F, 29 y |
36 |
N.A. |
N.A. |
Ibuprofen 600 mg/d |
Brancatella A et al. (55 Brancatella A, Ricci D, Cappellani D, Viola N, Sgrò D, Santini F, et al. Is subacute thyroiditis an underestimated manifestation of SARS-CoV-2 infection? Insights from a case series. J Clin Endocrinol Metab. 2020;105(10):dgaa537.) |
Italy |
F, 46 y |
20 |
TSH < 0.01 mIU/mL FT4 27.8 nmol/L FT3 6.9 pmol/L CRP 8 mg/L |
TSH 0.4-4.5 mIU/mL FT4 6-16 nmol/L FT3 2.3-4.2 pmol/L |
Prednisone 25 mg/d |
Campos-Barrera E et al. (66 Campos-Barrera E, Alvarez-Cisneros T, Davalos-Fuentes M. Subacute thyroiditis associated with Covid-19. Case Rep Endocrinol. 2020;2020:8891539.) |
Mexico |
F, 37 y |
30 |
TSH undetectable FT4 1.6 ng/dL CRP 66 mg/L ESR 72 mm/h |
N.A. |
N.A. |
Chakraborty U et al. (77 Chakraborty U, Ghosh S, Chandra A, Ray AK. Subacute thyroiditis as a presenting manifestation of COVID-19: a report of an exceedingly rare clinical entity. BMJ Case Rep. 2020;13(12):e239953.) |
India |
M, 58 y |
During SAT, SARS-CoV-2 PCR positive |
TSH < 0.005 mIU/L FT4 20.11 ug/dL FT3 2.88 ng/mL CRP 16.6 mg/L ESR 110 mm/h |
TSH 0.27-4.2 mIU/L FT4 5.10-14.1 ug/dL FT3 0.80-2.0 ng/mL |
Prednisolone 30 mg/d propranolol 40 mg/d |
Chong WH et al. (88 Chong WH, Shkolnik B, Saha B, Beegle S. Subacute Thyroiditis in the Setting of Coronavirus Disease 2019. Am J Med Sci. 2020:S0002-9629(20)30416-X.) |
USA |
M, 37 y |
30 |
TSH 0.01 mIU/L FT4 2.3 ng/dL CRP 14 mg/L ESR 31 mm/h |
TSH 0.4-4.5 mIU/L FT4 0.6-1.3 ng/dL |
NSAID |
Davoodi et al. (99 Davoodi L, Oladi Z, Jafarpour H, Zakariaei Z, Soleymani E, Razavi A. A 33-year-old man with COVID-19 presented with subacute thyroiditis: a rare case report and literature review. New Microbes New Infect. 2021;41:100871.) |
Iran |
M, 33 y |
During SAT, SARS-CoV-2 PCR positive |
TSH < 0.001 mIU/L tT4 23.1 ug/dL tT3 236 ng/dL CRP 37.9 mg/L ESR 84 mm/h |
TSH 0.5-5.0 mIU/L tT4 4-11 ug/dL tT3 75-195 ng/dL CRP <10 mg/L ESR <15 mm/h |
Dexamethasone 12 mg/d then prednisone 25 mg/d |
Dworakowska et al. (1010 Dworakowska D, Morley S, Mulholland N, Grossman AB. COVID-19-related thyroiditis: A novel disease entity? Clin Endocrinol (Oxf). 2021. doi:10.1111/cen.14453. https://doi.org/10.1111/cen.14453...
) |
UK |
F, 57 y |
appr. 60 |
anti-TPO, anti-Tg: positive |
N.A. |
Ibuprofen, paracetamol |
Ippolito S et al. (1111 Ippolito S, Dentali F, Tanda ML. SARS-CoV-2: a potential trigger for subacute thyroiditis? Insights from a case report. J Endocrinol Invest. 2020;43(8):1171-2.) |
Italy |
F, 69 y |
5, during SAT, SARS-CoV-2 PCR positive |
TSH 0.08 mIU/L FT4 24.6 pg/mL FT3 5.5 pg/mL |
TSH 0.27-4.2 mIU/L FT4 0.3-17 pg/mL FT3 2-4.4 pg/mL |
Methimazol, methylprednisolone 40 mg/d then prednisone 25 mg/d |
Khatri A et al. (1212 Khatri A, Charlap E, Kim A. Subacute thyroiditis from COVID-19 infection: a case report and review of literature. Eur Thyroid J. 2021;9(6):324-8.) |
USA |
F, 41 y |
28 |
TSH < 0.008 mIU/L TT4 222.91 nmol/L CRP 36.4 mg/L ESR 107 mm/h |
TSH 0.7-4.2 mIU/L TT4 59.34-154.8 nmol/L |
Ibuprofen 1,800 mg/d, prednisone 40 mg/d |
Mattar SAM et al. (1313 Mattar SAM, Koh SJQ, Rama Chandran S, Cherng BPZ. Subacute thyroiditis associated with COVID-19. BMJ Case Rep. 2020;13(8):e237336.) |
Singapore |
M, 34 y |
9, during SAT, SARS-CoV-2 PCR positive |
TSH < 0.01 mIU/L FT4 41.8 pmol/L FT3 13.4 pmol/L CRP 122 mg/L |
TSH 0.65-3.70 mIU/L FT4 8.8-14.4 pmol/L FT3 3.2-5.3 pmol/L |
Prednisone 20 mg/d, atenolol 25 mg/d |
Mehmood MA et al. (1414 Mehmood MA, Bapna M, Arshad M. A case of post-COVID-19 subacute thyroiditis. Cureus. 2020;12(12):e12301.) |
USA |
F, 29 y |
49 |
TSH 0.01 mIU/L FT4 4.4 ng/L FT3 374 ng/L CRP 44 mg/L ESR 84 mm/h |
TSH N.A. FT4 0.6-1.3 ng/L FT3 80-150 ng/L |
Prednisone 20 mg/d, atenolol 25 mg/d |
Muller I et al. (1515 Muller I, Cannavaro D, Dazzi D, Covelli D, Mantovani G, Muscatello A, et al. SARS-CoV-2-related atypical thyroiditis. Lancet Diabetes Endocrinol. 2020;8(9):739-41.) |
Italy |
M, 24 y |
During SAT, SARS-CoV-2 PCR positive |
TSH 0.33 mIU/L FT4 9.6 pmol/L FT3 4.0 pmol/L CRP 10 mg/L |
TSH 0.28-4.3 mIU/L FT4 10.3-21.9 pmol/L FT3 3.1-7.7 pmol/L |
N.A. |
Muller I et al. (1515 Muller I, Cannavaro D, Dazzi D, Covelli D, Mantovani G, Muscatello A, et al. SARS-CoV-2-related atypical thyroiditis. Lancet Diabetes Endocrinol. 2020;8(9):739-41.) |
Italy |
F, 59 y |
During SAT, SARS-CoV-2 PCR positive |
TSH 0.4 mIU/L FT4 16.6 pmol/L FT3 2.3 pmol/L CRP 233 mg/L |
TSH 0.28-4.3 mIU/L FT4 10.3-21.9 pmol/L FT3 3.1-7.7 pmol/L |
N.A. |
Muller I et al. (1515 Muller I, Cannavaro D, Dazzi D, Covelli D, Mantovani G, Muscatello A, et al. SARS-CoV-2-related atypical thyroiditis. Lancet Diabetes Endocrinol. 2020;8(9):739-41.) |
Italy |
M, 66 y |
During SAT, SARS-CoV-2 PCR positive |
TSH 0.43 mIU/L FT4 22.8 pmol/L CRP 52 mg/L |
TSH 0.28-4.3 mIU/L FT4 10.3-21.9 pmol/L FT3 3.1-7.7 pmol/L |
N.A. |
Ruano R et al. (1616 Ruano R, Zorzano-Martinez M, Campos A, Rius F, Hernández M. Subacute thyroiditis might be a complication triggered by SARS-CoV-2. Endocrinol Diabetes Nutr. 2020:S2530-0164(20)30206-8.) |
Spain |
F, 28 y |
29 |
TSH < 0.001 mIU/L FT4 37.5 pmol/L CRP 176 mg/L |
TSH 0.38-5.33 mIU/L FT4 7.0-16.0 pmol/L |
Paracetamol 1 g/8 h, aspirin 500 mg/d, propranolol 40 mg/d |
Ruggeri RM et al. (1717 Ruggeri RM, Campennì A, Siracusa M, Frazzetto G, Gullo D. Subacute thyroiditis in a patient infected with SARS-COV-2: an endocrine complication linked to the COVID-19 pandemic. Hormones (Athens). 2020;16:1-3.) |
Italy |
F, 43 y |
cca. 45 |
TSH 0.006 mIU/L FT4 2.69 ng/dL FT3 7.03 pg/mL |
TSH 0.27-4.2 mIU/L FT4 0.7-1.48 ng/dL FT3 1.71-3.71 pg/mL |
prednisone 25 mg/d |
San Juan MDJ et al. (1818 San Juan MDJ, Florencio MQV, Joven MH. Subacute thyroiditis in a patient with coronavirus diseases 2019. AACE Clin Case Rep. 2020;6(6):e361-4.) |
Philippines |
F, 47 y |
During SAT, SARS-CoV-2 PCR positive |
TSH 0.05 mIU/mL FT4 1.68 pg/mL CRP 5.09 mg/dL |
TSH 0.47-4.68 mIU/mL FT4 0.78-2.19 pg/mL |
NSAID |
Seyed Resuli A et al. (1919 Seyed Resuli A, Bezgal M. Subacute thyroiditis in COVID-19 patients. Ear Nose Throat J. 2021:1455613211012114.) |
Turkey |
F, 32 y |
During SAT, SARS-CoV-2 PCR positive |
FT4 26.8 pmol/L FT3 8.4 pmol/L ESR 65 mm/h |
FT4 12-22 pmol/L FT3 3-6 pmol/L |
Aspirin 3 g/d |
Seyed Resuli A et al. (1919 Seyed Resuli A, Bezgal M. Subacute thyroiditis in COVID-19 patients. Ear Nose Throat J. 2021:1455613211012114.) |
Turkey |
F, 25 y |
During SAT, SARS-CoV-2 PCR positive |
FT4 28.1 pmol/L FT3 9.6 pmol/L ESR 58 mm/h |
FT4 12-22 pmol/L FT3 3-6 pmol/L |
Aspirin 3 g/d |
Seyed Resuli A et al. (1919 Seyed Resuli A, Bezgal M. Subacute thyroiditis in COVID-19 patients. Ear Nose Throat J. 2021:1455613211012114.) |
Turkey |
F, 45 y |
During SAT, SARS-CoV-2 PCR positive |
FT4 43.1 pmol/L FT3 14.2 pmol/L ESR 70 mm/h |
FT4 12-22 pmol/L FT3 3-6 pmol/L |
Aspirin 3 g/d, prednisolone 1 mg/kg/d |
Seyed Resuli A et al. (1919 Seyed Resuli A, Bezgal M. Subacute thyroiditis in COVID-19 patients. Ear Nose Throat J. 2021:1455613211012114.) |
Turkey |
F, 29 y |
During SAT, SARS-CoV-2 PCR positive |
FT4 38.1 pmol/L FT3 11.3 pmol/L ESR 65 mm/h |
FT4 12-22 pmol/L FT3 3-6 pmol/L |
Aspirin 3 g/d |
Seyed Resuli A et al. (1919 Seyed Resuli A, Bezgal M. Subacute thyroiditis in COVID-19 patients. Ear Nose Throat J. 2021:1455613211012114.) |
Turkey |
F, 21 y |
During SAT, SARS-CoV-2 PCR positive |
FT4 43.5 pmol/L FT3 16.2 pmol/L ESR 80 mm/h |
FT4 12-22 pmol/L FT3 3-6 pmol/L |
Aspirin 3 g/d, prednisolone 1 mg/kg/d |
Sohrabpour S et al. (2020 Sohrabpour S, Heidari F, Karimi E, Ansari R, Tajdini A, Heidari F. Subacute thyroiditis in COVID-19 patients. Eur Thyroid J. 2020;1-3.) |
Iran |
F, 26 y |
N.A. |
TSH 0.07 mIU/L FT4 19.5 pmol/L FT3 18.9 pmol/L CRP 28 mg/L ESR 70 mm/h |
TSH 0.4-4.0 mIU/L FT4 12-21 pmol/L FT3 3.1-6.8 pmol/L |
Prednisone 25 mg/d |
Sohrabpour S et al. (2020 Sohrabpour S, Heidari F, Karimi E, Ansari R, Tajdini A, Heidari F. Subacute thyroiditis in COVID-19 patients. Eur Thyroid J. 2020;1-3.) |
Iran |
F, 37 y |
N.A. |
TSH < 0.01 mIU/L FT4 2.3 pmol/L FT3 25.4 pmol/L CRP 38 mg/L ESR 56 mm/h |
TSH 0.4-4.0 mIU/L FT4 12-21 pmol/L FT3 3.1-6.8 pmol/L |
Prednisone 25 mg/d |
Sohrabpour S et al. (2020 Sohrabpour S, Heidari F, Karimi E, Ansari R, Tajdini A, Heidari F. Subacute thyroiditis in COVID-19 patients. Eur Thyroid J. 2020;1-3.) |
Iran |
M, 35 y |
N.A. |
TSH 0.12 mIU/L FT4 24.7 pmol/L FT3 19.3 pmol/L CRP 18 mg/L ESR 45 mm/h |
TSH 0.4-4.0 mIU/L FT4 12-21 pmol/L FT3 3.1-6.8 pmol/L |
Prednisone 25 mg/d |
Sohrabpour S et al. (2020 Sohrabpour S, Heidari F, Karimi E, Ansari R, Tajdini A, Heidari F. Subacute thyroiditis in COVID-19 patients. Eur Thyroid J. 2020;1-3.) |
Iran |
F, 41 y |
N.A. |
TSH < 0.01 mIU/L FT4 21.9 pmol/L FT3 23.7 pmol/L CRP 43 mg/L ESR 83 mm/h |
TSH 0.4-4.0 mIU/L FT4 12-21 pmol/L FT3 3.1-6.8 pmol/L |
Prednisone 25 mg/d |
Sohrabpour S et al. (2020 Sohrabpour S, Heidari F, Karimi E, Ansari R, Tajdini A, Heidari F. Subacute thyroiditis in COVID-19 patients. Eur Thyroid J. 2020;1-3.) |
Iran |
M, 52 y |
N.A. |
TSH 0.17 mIU/L FT4 26.7 pmol/L FT3 21.6 pmol/L CRP 51 mg/L ESR 76 mm/h |
TSH 0.4-4.0 mIU/L FT4 12-21 pmol/L FT3 3.1-6.8 pmol/L |
Prednisone 25 mg/d |
Sohrabpour S et al. (2020 Sohrabpour S, Heidari F, Karimi E, Ansari R, Tajdini A, Heidari F. Subacute thyroiditis in COVID-19 patients. Eur Thyroid J. 2020;1-3.) |
Iran |
F, 34 y |
N.A. |
TSH 0.23 mIU/L FT4 18.4 pmol/L FT3 18.1 pmol/L CRP 23 mg/L ESR 39 mm/h |
TSH 0.4-4.0 mIU/L FT4 12-21 pmol/L FT3 3.1-6.8 pmol/L |
Prednisone 25 mg/d |
Hajósi-Kalcakosz Sz et al.
|
Hungary |
F, 31 y |
35 |
TSH 0.046 uIU/mL FT4 1.60 ng/dL FT3 4.10 pg/mL CRP 16.9 mg/L ESR 34 mm/h |
TSH 0.35-4.94 uIU/mL FT4 0.7-1.48 ng/dL FT3 1.71-3.71 pg/mL |
Methylprednisolone 32 mg/d |