Causes and pathological aspects of neuroinflammatory diseases of the central nervous system in catsNeuroinflammatory diseases in cats can have various causes; however, comprehensive studies on these conditions are limited. This study described the causes and pathological aspects of 60 cases of inflammatory lesions in the central nervous system (CNS) of domestic cats based on a 10-year retrospective analysis of necropsies. Infectious diseases were identified in 47 of 60 cases (78.3%), including viral (28/60, 46.7%), fungal (9/60, 15%), bacterial (5/60, 8.3%) and parasitic (5/60, 8.3%) infections. The main aetiological agent was feline infectious peritonitis virus (27/60, 45%), followed by Cryptococcus sp. (9/60, 15%), Streptococcus sp. (4/60, 6.7%), Toxoplasma gondii (2/60, 3.3%), Gurltia paralysans (2/60, 3.3%), rabies virus (1/60, 1.6%) and Sarcocystis neurona (1/60, 1.6%). The most frequent histopathological lesions were pyogranulomatous and granulomatous meningoencephalitis. Our results highlighted the most common neuroinflammatory diseases affecting the feline CNS and underscore the importance of thorough diagnostic processes. Detailed pathological analysis and supplementary laboratory tests are crucial for the accurate diagnosis of these neurologic conditions.
Key words:
central nervous system; feline; Felis catus; neuropathology; feline infectious peritonitis virus
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