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Associated dental anomalies: the orthodontist decoding the genetics which regulates the dental development disturbances

This article aims to approach the diagnosis and orthodontic intervention of the dental anomalies, emphasizing the etiological aspects which define these developmental irregularities. It seems to exist a genetic inter-relationship determining some dental anomalies, considering the high frequency of associations. The same genetic defect may give rise to different phenotypes, including tooth agenesis, microdontia, ectopias and delayed dental development. The clinical implications of the associated dental anomalies are relevant, since early detection of a single dental anomaly may call the attention of professionals to the possible development of other associated anomalies in the same patient or in the family, allowing timely orthodontic intervention.

Genetics; Dental anomalies; Tooth agenesis; Etiology; Orthodontics


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