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• Mem. Inst. Oswaldo Cruz 76 (1) • Mar 1981 • https://doi.org/10.1590/S0074-02761981000100010 linkcopy

Open-access On the adjuvant effect of aluminum hydroxide for mice

AuthorshipSCIMAGO INSTITUTIONS RANKINGS

Abstract

Linear relationships were found between the dose of A1(OH)3 adjuvant and the titer of anti-OVA antibodies formed by BDF1 mice. Mice immunized with OVA, DNP-KLH and then boosted with DNP-OVA formed anti-DNP antibodies only when A1(OH)3 was added to the injection of DNP-KLH; addition of A1(OH)3 to the priming injection of OVA decreased, rather than increased antibody formation.

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