Helicobacter pylori in dyspeptic children and adults: endoscopic, bacteriologic and histologic correlationsAbstract
Using different bacteriological (urease test, Gram staining and culture) and histological (Steiner staining and modified Giemsa staining) techniques, we searched for the presence of Helicobacter pylori in the gastric antrum of 200 dyspeptic Brazilian patients (106 females and 94 males aged 19 days to 81 years). The presence of bacteria was then correlated with the endoscopic and histological findings. H. pylori was present in 59.5 of the population studied. In Brazil, colonization occurs early, involving 37 of the dyspeptic population by 20 years of age. The presence of H. pylori in the gastric antrum was strongly associated with duodenal ulcer (P < 0.001) and a normal endoscopic examination did not exclude the possibility of colonization of the gastric antrum by H. pylori. The most sensitive test was the preformed urease test (89). We conclude that more than one diagnostic method should preferably be used for the detection of H. pylori and that the presence of H. pylori is closely correlated with active chronic gastritis (P < 0.001).
Helicobacter pylori; gastric ulcer; duodenal ulcer; adults; children
Helicobacter pylori in dyspeptic children and adults: endoscopic, bacteriologic and histologic correlations
Claude A. Solari1
Roberta P. N. Araruna2
Eliane M. F. Reis2
Ernesto Hofer3
Graça Dias4
Glória Moraes5
Carlos A. Basilio6
Charisse M. S. Rodriguez6
Luiz L. Luna6
Universidade Federal do Rio de Janeiro, Escola de Medicina e Cirurgia, Departamento de Patologia e Apoio Clínico, Rio de Janeiro, Brasil
Instituto Oswaldo Cruz, Departamento de Bacteriologia, Rio de Janeiro, Brasil
Universidade Federal do Rio de Janeiro, Faculdade de Farmácia, Departamento de Higiene Social e Análises Clínicas, Rio de Janeiro, Brasil
Hospital São Vicente de Paulo, Instituto Fernandes Figueira, Serviços de Anatomia Patológica e de Endoscopia Digestiva, Rio de Janeiro, Brasil
Instituto Fernandes Figueira, Serviços de Anatomia Patológica e de Endoscopia Digestiva, Rio de Janeiro, Brasil
Hopsital São Vicente de Paulo, Serviços de Anatomia Patológica Cirúrgica e de Endoscopia Digestiva, Rio de Janeiro, Brasil
Using different bacteriological (urease test, Gram staining and culture) and histological (Steiner staining and modified Giemsa staining) techniques, we searched for the presence of Helicobacter pylori in the gastric antrum of 200 dyspeptic Brazilian patients (106 females and 94 males aged 19 days to 81 years). The presence of bacteria was then correlated with the endoscopic and histological findings. H. pylori was present in 59.5 of the population studied. In Brazil, colonization occurs early, involving 37 of the dyspeptic population by 20 years of age. The presence of H. pylori in the gastric antrum was strongly associated with duodenal ulcer (P < 0.001) and a normal endoscopic examination did not exclude the possibility of colonization of the gastric antrum by H. pylori. The most sensitive test was the preformed urease test (89). We conclude that more than one diagnostic method should preferably be used for the detection of H. pylori and that the presence of H. pylori is closely correlated with active chronic gastritis (P < 0.001).
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Publication Dates
-
Publication in this collection
01 June 2009 -
Date of issue
Dec 1994
