Acessibilidade / Reportar erro

Preparation of antigens (Leprolins Souza-Araujo) from cultures of acidfast bacilli isolated from lepers: its use intracutaneous, comparatively with Lepromin, and subcutaneous or intravenously as therapeutics

The A. prepared five antigens from his leprosy cultures which by analogy with ROST's product he called Leprolins. The methods of its preparation and use are given. After a few tests to prove its innocuity for man the A. in cooperation with Dr. JOSÉ MARIANO, injected all five antigens intracutaneously in 120 patients. Now the products are being tested in 17 Leper Colonies of Brazil, in Argentina by Dr. SALOMON SCHUJMAN and in two leprosaria of Colombia. As antigen for skin tests the first results obtained are more or less identical with the results with Lepromin. Its use in serology for leprosy diagnosis will be made by Dr. T. PINTO of Rio, and Prof. LUIZ PRADO BARRIENTOS, of La Paz, Bolivia. As curative means the Leprolins are being injected into resistent lesions of leprosy and also by intraven injections, whose results Dr. José Mariano will publish soon. The Leprolins Souza-Araujo are put at disposal of all leprologists interested in its use.


Instituto Oswaldo Cruz, Ministério da Saúde Av. Brasil, 4365 - Pavilhão Mourisco, Manguinhos, 21040-900 Rio de Janeiro RJ Brazil, Tel.: (55 21) 2562-1222, Fax: (55 21) 2562 1220 - Rio de Janeiro - RJ - Brazil
E-mail: memorias@fiocruz.br