The purpose of this study was to analise late anatomical status of coronary arteries in patients (pts) in whom orthotopic heart transplantation(OHT) was perfomed. We studied 22 pts submitted to OHT with post-operative follow-up longer than 36 months. They were evaluated by cinecoronariography every year in a 5 years follow-up. Ventriculography analisis showed stability (in normal values) of the left ventricular ejection fraction (p= 0,99) during the follow-up period. The sequential coronary studies showed a progressive increase on incidence of abnormalities in coronary arteries with disorders of contratile function. The obstructive abnormalities were present in all segments but more in distal territories. The acute rejection episodes and cardiomiopathy etiologies didn't change the natural evolution of coronary atherosclerosis.
heart transplantation; heart transplantation; heart transplatation; heart transplantation