Predictors of fluid intravasation during operative hysteroscopy: a preplanned prospective observational study with 200 cases

Preditores de intravasamento durante histeroscopia cirúrgica: um estudo observacional prospectivo com 200 casos

Márlon de Freitas Fonseca Claudio Moura Andrade Junior Eduardo de Almeida Nogueira Felipe Ventura Sessa Claudio Peixoto Crispi About the authors


To verify the predictors of intravasation rate during hysteroscopy.


Prospective observational study (Canadian Task Force classification II-1). All cases (n=200 women; 22 to 86 years old) were treated in an operating room setting. Considering respective bag overfill to calculate water balance, we tested two multiple linear regression models: one for total intravasation (mL) and the other for absorption rate (mL.min-1). The predictors tested (independent variables) were energy (mono/bipolar), tube patency (with/without tubal ligation), hysterometry (cm), age≤50 years, body surface area (m2), surgical complexity (with/without myomectomy) and duration (min).


Mean intravasation was significantly higher when myomectomy was performed (442±616 versus 223±332 mL; p<0.01). In the proposed multiple linear regression models for total intravasation (adjusted R2=0.44; p<0.01), the only significant predictors were myomectomy and duration (p<0.01).In the proposed model for intravasation rate (R2=0.39; p<0.01), only myomectomy and hysterometry were significant predictors (p=0.02 and p<0.01, respectively).


Not only myomectomy but also hysterometry were significant predictors of intravasation rate during operative hysteroscopy.

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