ACUTE EFFECT OF AEROBIC EXERCISE OF DIFFERENT INTENSITIES IN CYTOKINES OF UNIVERSITY STUDENTS

EFEITO AGUDO DO EXERCÍCIO AERÓBICO DE DIFERENTES INTENSIDADES EM CITOCINAS DE UNIVERSITÁRIOS

EFECTO AGUDO DEL EJERCICIO AERÓBICO DE DIFERENTES INTENSIDADES EN CITOQUINAS DE UNIVERSITARIOS

ABSTRACT

Introduction:

A single exercise training session promotes stimuli for changes in the immune system that are cumulatively considered adaptations to the exercise.

Objective:

This paper explores the acute effect of different intensities of aerobic exercise on anti-inflammatory and proinflammatory markers in apparently healthy university students.

Methods:

Eighteen volunteers underwent two sessions of aerobic exercise, the first at 65-70% estimated heart rate (HR), and after seven days, a second session at 80-85% HR. Before and after each session, venous blood was drawn, in order to analyze interleukin (IL) 6 and 10 in a Milliplex Kit. The participants’ level of physical activity was determined using a questionnaire. For statistical comparisons, two-way ANOVA was used for the variables hemodynamics and perceived exertion. The cytokine results were compared through the Student's t-test for repeated measurements. The exclusion criteria were the practice of physical exercise and having drunk alcohol on the day before the intervention sessions, the presence of osteomioarticular conditions, and missing one of the sessions.

Results:

This study showed that IL-6 was not significantly decreased when comparing the two sessions. IL-10 was significantly decreased (p=0.033) in the 65-70% HR session but not in the 80-85% HR session. The delta variation for IL-10 showed a tendency (p=0.053) towards a greater decrease in the 65-70% HR session when compared to the 80-85% HR session. There were no differences in the acute effect of exercise when comparing the levels of physical activity.

Conclusion:

This study highlights that two different zones of high intensity exercise can induce different inflammatory responses, as demonstrated by the significant decrease in IL-10 in the 65-70%HR zone. The study also shows that there was no difference in physical exercise response in individuals with moderate and high physical activity levels. Level of evidence III; Comparative study.

Keywords:
Interleukin-6; Interleukin-10; Inflammation