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Evaluation of the intraocular pressure behavior in patients with assimetric primary open-angle glaucoma submitted to ibopamine provocative test

OBJECTIVE: To evaluate the topic 2% ibopamine effect in the intraocular pressure (IOP) of eyes with assimetric primary open-angle glaucoma (POAG). METHODS: 15 patients (30 eyes) with primary open-angle glaucoma showing assimetric nerve disease evolution were assessed. We compared in all patients, the ibopamine response and the visual field defect between both eyes. The visual field, to be considered, should have at least 5 dB in MD difference between them. The statistical analysis was done with the Two-Tailed Student Test, with a Statistics significance of p<0.05. RESULTS: In 80% of the cases, (12/15 patients), the most affected eye in the visual field presented a greater variation and/or higher intraocular pressure after the ibopamine provocative test. The difference was statistically significant (p<0.00001 and p= 0.0006) respectively. CONCLUSION: This study showed that the visual field defect in GPAA is significantly connected with the positivity of the ibopamine test. The most affected eyes in the visual field presented a higher intraocular pressure (max-PIO) and/or a greater variation (v-PIO) after the ibopamine provocativetest.

Intraocular pressure; Glaucoma, open-angle; Visual fields; Perimetry; Ophthalmic solutions; Ophthalmic solutions; Deoxyepinephrine; Deoxyepinephrine; Deoxyepinephrine; Deoxyepinephrine; Mydriatics


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