Drug-Resistant Tuberculosis and COVID-19: A Scoping Review on a New Threat to Antimicrobial Resistance

Silva, Beibilene Perlato Melo da; Almeida, Anelisa Soares de; Sérgio, Matheus Gabriel de Melo; Gatto, Thamires Carraro; Carasek, Vinícius Paglione; Yamamura, Mellina

doi:10.1590/0034-7167-2022-0803

Beibilene Perlato Melo da Silva Corresponding author: Beibilene Perlato Melo da Silva E-mail: beibilene@estudante.ufscar.br

analysis and/or interpretation of the data

final review with critical and intellectual participation in the manuscript

Universidade Federal de São Carlos. São Carlos, São Paulo, Brazil

https://orcid.org/0000-0003-0460-5819

Anelisa Soares de Almeida

analysis and/or interpretation of the data

final review with critical and intellectual participation in the manuscript

Universidade Federal de São Carlos. São Carlos, São Paulo, Brazil

https://orcid.org/0000-0002-4969-4555

Matheus Gabriel de Melo Sérgio

conception or design of the study/research

analysis and/or interpretation of the data

Universidade Federal de São Carlos. São Carlos, São Paulo, Brazil

https://orcid.org/0000-0002-5735-3398

Thamires Carraro Gatto

analysis and/or interpretation of the data

Universidade Federal de São Carlos. São Carlos, São Paulo, Brazil

https://orcid.org/0000-0002-4667-8111

Vinícius Paglione Carasek

analysis and/or interpretation of the data

Universidade Federal de São Carlos. São Carlos, São Paulo, Brazil

https://orcid.org/0000-0002-9255-0338

Mellina Yamamura

conception or design of the study/research

analysis and/or interpretation of the data

final review with critical and intellectual participation in the manuscript

Universidade Federal de São Carlos. São Carlos, São Paulo, Brazil

https://orcid.org/0000-0001-5228-8788

Corresponding author: Beibilene Perlato Melo da Silva E-mail: beibilene@estudante.ufscar.br

EDITOR IN CHIEF: Dulce Barbosa

ASSOCIATE EDITOR: Luís Carlos Lopes Júnior

Data base	Search
National Library of Medicine’s (NLM/PubMed)	((tuberculosis OR Mycobacterium tuberculosis) AND (Extensively Drug- Resistant Tuberculosis OR Tuberculosis, Multidrug-Resistant OR Mycobacterium tuberculosis, susceptibility to infection by Drug Resistance OR Drug Resistance, Bacterial OR Drug Resistance, Microbial OR Drug Resistance, Multiple)) AND (COVID-19 OR 2019-nCoV infection OR coronavirus disease 2019 OR COVID-19 pandemic OR 2019-nCoV disease OR 2019 novel coronavirus disease OR 2019 novel coronavirus infection OR coronavirus disease-19)
SciVerse Scopus (Elsevier)	( TITLE-ABS-KEY ( tuberculosis ) OR TITLEABS-KEY (mycobacterium AND tuberculosis ) AND TITLE-ABS-KEY ( extensively AND drug-resistant AND tuberculosis ) OR TITLE-ABS-KEY ( extensively AND drug-resistant AND tuberculosis ) OR TITLE-ABS- KEY ( mycobacterium AND tuberculosis, AND susceptibility AND to AND infection AND by AND drug AND resistance ) OR TITLE-ABS- KEY ( drug AND resistance, AND bacterial ) OR TITLE-ABS-KEY ( drug AND resistance, AND microbial ) OR TITLE-ABS-KEY ( drug AND resistance, AND multiple ) AND TITLE-ABS-KEY ( covid-19 ) OR TITLEABS-KEY ( corvidae ) OR TITLE-ABS-KEY ( 2019-ncov AND infection) OR TITLE-ABS-KEY ( coronavirus AND disease 2019 ) OR TITLE-ABS-KEY ( covid-19 AND pandemic ) OR TITLE-ABS-KEY (2019-ncov AND disease) OR TITLEABS-KEY ( 2019 novel AND coronavirus AND disease ) OR TITLE-ABS-KEY ( 2019 novel AND coronavirus AND infection ) OR TITLE-ABS-KEY ( coronavirus AND disease-19 ) )
Web of Science (WoS)	((ALL=(tuberculosis OR Mycobacterium tuberculosis)) AND ALL=(Extensively Drug-Resistant Tuberculosis OR Tuberculosis, Multidrug-Resistant OR Mycobacterium tuberculosis, susceptibility to infection by Drug Resistance OR Drug Resistance, Bacterial OR Drug Resistance, Microbial OR Drug Resistance, Multiple)) AND ALL=(COVID-19 OR 2019-nCoV infection OR coronavirus disease 2019 OR COVID-19 pandemic OR 2019-nCoV disease OR 2019 novel coronavirus disease OR 2019 novel coronavirus infection OR coronavirus disease-19
Virtual Health Library	((tuberculosis) OR (mycobacterium tuberculosis) AND (extensively drug- resistant tuberculosis) OR (tuberculosis, multidrug-resistant) OR (mycobacterium tuberculosis, susceptibility TO infection by drug resistance) OR (drug resistance, bacterial) OR (drug resistance, microbial) OR (drug resistance, multiple) AND (covid-19) OR (covid19) OR (2019- ncov infection) OR (coronavirus disease 2019) OR (covid-19 pandemic) OR (2019-ncov disease) OR (2019 novel coronavirus disease) OR (2019 novel coronavirus infection) OR (coronavirus disease-19))

Study Type	n	%	Studies
Letter to the editor or comment	13	37.14	E1(¹⁹19 Gray AT, Boyles T, Luedtke S, Sossen B, Birjovanu G, Kostkova P, et al. A threat to decentralised care for drug-resistant tuberculosis. Lancet Respir Med. 2020;8(10):950-2. https://doi.org/10.1016/S2213-2600(20)30392-1 https://doi.org/10.1016/S2213-2600(20)30... ), E4(²⁰20 Rawson TM, Ming D, Ahmad R, Mooree LSP, Holmes AH. Antimicrobial use, drug-resistant infections and COVID-19. Nat Rev Microbiol. 2020;18:409–10. https://doi.org/10.1038/s41579-020-0395-y https://doi.org/10.1038/s41579-020-0395-... ), E7(⁴4 Islam, M. Extensively Drug-Resistant Tuberculosis in the Time of COVID-19—How has the Landscape Changed for Pakistan? Disaster Medicine and Public Health Preparedness. 2020;14(4). https://doi.org/10.1017/dmp.2020.230 https://doi.org/10.1017/dmp.2020.230... ), E9(²¹21 Ndjeka N, Conradie F, Meintjes G, Reuter A, Hughes J, Padanilam X, et al. Responding to SARS- CoV-2 in South Africa: what can we learn from drug-resistant tuberculosis? Eur Respir J. 2020;56(1):2001369. https://doi.org/10.1183/13993003.01369-2020 https://doi.org/10.1183/13993003.01369-2... ), E10(²²22 Long Q, Huang, F, Huan, ST, Zhao YL. Scale-up of a comprehensive model to improve tuberculosis control in China: lessons learned and the way forward. Infect Dis Poverty. 2021;10(41). https://doi.org/10.1186/s40249-021-00828-1 https://doi.org/10.1186/s40249-021-00828... ), E13(¹³13 Coronel TR, Aguirre S, Pérez BD. Thinking about tuberculosis in times of COVID-19. J Intern Med. 2021 Apr;289(4):589-590. https://doi.org/10.1111/joim.13192 https://doi.org/10.1111/joim.13192... ), E14(²³23 Mohr-Holland E, Douglas-Jones B, Apolis I, Ngambu N, Mathee S, Cariem R. Tuberculosis preventive therapy for children and adolescents: an emergency response to the COVID-19 pandemic. Lancet Child Adolesc Health. 2021;5(3):159-61. https://doi.org/10.1016/S2352-4642(21)00003-1 https://doi.org/10.1016/S2352-4642(21)00... ), E15(²⁴24 Migliori GB, Tiberi S, García-Basteiro AL, Duarte R. Tuberculosis and its future in the COVID- 19 era: the pulmonology series 2021. Pulmonology. 2021;27(2):94-6. https://doi.org/10.1016/j.pulmoe.2020.10.005 https://doi.org/10.1016/j.pulmoe.2020.10... ), E16(⁷7 Buonsenso D, Iodice F, Biala JS, Goletti D. COVID-19 effects on tuberculosis care in Sierra Leone, Pulmonology. 2021;27(1):67-69. https://doi.org/10.1016/j.pulmoe.2020.05.013 https://doi.org/10.1016/j.pulmoe.2020.05... ), E17(²⁵25 Meneguim AC, Rebello L, Das M, Ravi S, Mathur T, Mankar S, et al. Adapting TB services during the COVID-19 pandemic in Mumbai, India. Int J Tuberc Lung Dis. 2020;24(10):1119-21. https://doi.org/10.5588/ijtld.20.0537 https://doi.org/10.5588/ijtld.20.0537... ), E18(²⁶26 Liu C, Yu Y, Fleming J, Wang T, Shen S, Wang Y, et al. Severe COVID-19 cases with a history of active or latent tuberculosis. Int J Tuberc Lung Dis. 2020;24(7):747-9. https://doi.org/10.5588/ijtld.20.0163 https://doi.org/10.5588/ijtld.20.0163... ), E21(²⁷27 Mohr-Holland E, Hacking D, Daniels J, Scott V, Mudaly V, Furin J, et al. Diagnosis patterns for rifampicin-resistant TB after onset of COVID-19. Int J Tuberc Lung Dis. 2021;25(9):772-5. https://doi.org/10.5588/ijtld.21.0340 https://doi.org/10.5588/ijtld.21.0340... ), E25(²⁸28 Parums DV. Editorial: Updates from the World Health Organization (WHO) on Global Treatment Recommendations for Drug-Susceptible and Multidrug-Resistant Tuberculosis. Med Sci Monit. 2021;27:e934292. https://doi.org/10.12659/MSM.934292 https://doi.org/10.12659/MSM.934292... )
Reviews	11	31.42	E2(¹⁰10 Stagg HR, Flook M, Martinecz A, Kielmann K, Wiesch PAZ, Karat AS, et al. All nonadherence is equal but is some more equal than others? tuberculosis in the digital era. ERJ Open Research. 2020;6(4):00315-2020. https://doi.org/10.1183/23120541.00315-2020 https://doi.org/10.1183/23120541.00315-2... ), E3(²⁹29 Knight GM, Glover RE, McQuaid CF, Olaru ID, Galland K, Leclerc Q, et al. Antimicrobial resistance and COVID-19: intersections and implications. Epidemiol Glob Health. 2021;10:e64139. https://doi.org/10.7554/eLife.64139 https://doi.org/10.7554/eLife.64139... ), E6(¹²12 Allué-Guardia A, García JI, Torrelles JB. Evolution of Drug-Resistant Mycobacterium tuberculosis Strains and Their Adaptation to the Human Lung Environment. Frontiers in Microbiology. 2021;12. https://doi.org/10.3389/fmicb.2021.612675 https://doi.org/10.3389/fmicb.2021.61267... ), E8(³⁰30 Tamuzi JL, Ayele BT, Shumba CS, Adetokunboh OO, Uwimana-Nicol J, Haile ZT, et al. Implications of COVID-19 in high burden countries for HIV/TB: a systematic review of evidence. BMC Infect Dis. 2020;744. https://doi.org/10.1186/s12879-020-05450-4 https://doi.org/10.1186/s12879-020-05450... ), E11(⁶6 Migliori GB, Visca D, van den Boom M, Tiberi S, Silva DR, Centis R, et al. Tuberculosis, COVID-19 and hospital admission: consensus on pros and cons based on a review of the evidence. Pulmonology. 2021;27(3):248-56. https://doi.org/10.1016/j.pulmoe.2020.12.016 https://doi.org/10.1016/j.pulmoe.2020.12... ), E20(³¹31 Lobie TA, Roba AA, Booth JA, Kristiansen KI, Aseffa A, Skarstad K, et al Antimicrobial resistance: a challenge awaiting the post-COVID-19 era. Int J Infect Dis. 2021;111:322-5. https://doi.org/10.1016/j.ijid.2021.09.003 https://doi.org/10.1016/j.ijid.2021.09.0... ), E22(³²32 Ramasamy P, Sounderrajan V, Vijayakumar KK, Harshavardhan S. Current Perceptions on Advanced Molecular Diagnostics for Drug-Resistant Mycobacterium tuberculosis. Biomed Pharmacol J. 2021;14(3). https://doi.org/10.13005/bpj/2226 https://doi.org/10.13005/bpj/2226... ), E24(³³33 Wingfield T, Karmadwala F, MacPherson P, Millington KA, Walker NF, Cuevas LE, Squire SB. Challenges and opportunities to end tuberculosis in the COVID-19 era. Lancet Respir Med. 2021;9(6):556-8. https://doi.org/10.1016/S2213-2600(21)00161-2 https://doi.org/10.1016/S2213-2600(21)00... ), E28(⁸8 Tiberi S, Vjecha MJ, Zumla A, Galvin J, Migliori GB, Zumla A. Accelerating development of new shorter TB treatment regimens in anticipation of a resurgence of multi-drug resistant TB due to the COVID-19 pandemic. Int J Infect Dis. 2021;113(Suppl-1):S96-S99. https://doi.org/10.1016/j.ijid.2021.02.067 https://doi.org/10.1016/j.ijid.2021.02.0... ), E31(³⁴34 Caren GJ, Iskandar D, Pitaloka DAE, Abdulah R, Suwantika AA. COVID-19 Pandemic Disruption on the Management of Tuberculosis Treatment in Indonesia. J Multidiscip Healthc. 2022;15:175-83. https://doi.org/10.2147/JMDH.S341130 https://doi.org/10.2147/JMDH.S341130... ), E34(³⁵35 du Preez K, Gabardo BMA, Kabra SK, Triasih R, Lestari T, Kal M, et al. Priority Activities in Child and Adolescent Tuberculosis to Close the Policy-Practice Gap in Low-and Middle-Income Countries. Pathogens. 2022;11(2):196. https://doi.org/10.3390/pathogens11020196 https://doi.org/10.3390/pathogens1102019... )
Qualitative	2	5.71	E27(³⁶36 Souza LLL, Santos FLD, Crispim JA, Fiorati RC, Dias S, Bruce ATI, et al. Causes of multidrug - resistant tuberculosis from the perspectives of health providers: challenges and strategies for adherence to treatment during the COVID-19 pandemic in Brazil. BMC Health Serv Res. 2021;21(1):1033. https://doi.org/10.1186/s12913-021-07057-0 https://doi.org/10.1186/s12913-021-07057... ), E35(⁹9 Santos FLD, Souza LLL, Bruce ATI, Crispim JA, Arroyo LH, Ramos ACV, et al. Patients' perceptions regarding multidrug-resistant tuberculosis and barriers to seeking care in a priority city in Brazil during COVID-19 pandemic: a qualitative study. PLoS One. 2021;16(4):e0249822. https://doi.org/10.1371/journal.pone.0249822 https://doi.org/10.1371/journal.pone.024... )
Case report	3	8.57	E5(³⁷37 Vilbrun SC, Mathurin L, Pape JW, Fitzgerald D, Walsh KF. Case Report: Multidrug-Resistant Tuberculosis and COVID-19 Coinfection in Port-au-Prince, Haiti. Am J Trop Med Hyg. 2020;103(5):1986-8. https://doi.org/10.4269/ajtmh.20-0851 https://doi.org/10.4269/ajtmh.20-0851... ), E26(³⁸38 Marwah V, Peter DK, Ajai Kumar T, Bhati G, Kumar A. Multidrug-resistant tuberculosis in COVID-19: Double trouble. Med J Armed Forces India. 2021;77(Suppl-2):S479-S482. https://doi.org/10.1016/j.mjafi.2021.05.002 https://doi.org/10.1016/j.mjafi.2021.05.... ), E30(³⁹39 Yadav S, Rawal G. Primary multidrug-resistant pulmonary tuberculosis with a concomitant COVID-19 infection in an Indian female- World's first case of its type in this current pandemic. J Family Med Prim Care. 2021;10(10):3922-4. https://doi.org/10.4103/jfmpc.jfmpc_225_21 https://doi.org/10.4103/jfmpc.jfmpc_225_... )
Descriptive observational	3	8.57	E19(⁴⁰40 Arega B, Negesso A, Taye B, Weldeyohhans G, Bewket B, Negussie T, et al. Impact of COVID-19 pandemic on TB prevention and care in Addis Ababa, Ethiopia: a retrospective database study. BMJ Open. 2022;12(2):e053290. https://doi.org/10.1136/bmjopen-2021-053290 https://doi.org/10.1136/bmjopen-2021-053... ), E23(⁴¹41 Kuchukhidze G, Yedilbayev A, Perehinets I, Schmidt T, Van Grinsven WL, Boeree MJ. Early COVID-19 pandemic’s toll on tuberculosis services, WHO European Region, January to June 2020. Euro Surveill. 2021;26(24):2100231. https://doi.org/10.2807/1560-7917.ES.2021.26.24.2100231 https://doi.org/10.2807/1560-7917.ES.202... ), E33(¹¹11 Dean AS, Auguet OT, Glaziou P, Zignol M, Ismail N, Kasaeva T, et al. 25 years of surveillance of drug-resistant tuberculosis: achievements, challenges, and way forward. Lancet Infect Dis. 2022;22(7):e191-e196. https://doi.org/10.1016/S1473-3099(21)00808-2 https://doi.org/10.1016/S1473-3099(21)00... )
Retrospective cohort	2	5.71	E12(⁴²42 Gajbhiye RK, Mahajan NN, Kamath N, Bahirat S, Patokar G, Bhurke AV, et al. Clinical presentations, pregnancy complications, and maternal outcomes in pregnant women with COVID-19 and tuberculosis: a retrospective cohort study. Int J Gynaecol Obstet. 2021;153(1):176-9. https://doi.org/10.1002/ijgo.13588 https://doi.org/10.1002/ijgo.13588... ), E32(⁵5 Hasan T, Nguyen VN, Nguyen HB, Nguyen TA, Le HTT, Pham CD, et al. Retrospective Cohort Study of Effects of the COVID-19 Pandemic on Tuberculosis Notifications, Vietnam, 2020. Emerg Infect Dis. 2022;28(3):684-92. https://doi.org/10.3201/eid2803.211919 https://doi.org/10.3201/eid2803.211919... )
Ecological	1	2.86	E29(⁴⁶46 Gao GY, Liu M, Chen Y, Shi S, Geng J, Tian J. Association between tuberculosis and COVID-19 severity and mortality: a rapid systematic review and meta-analysis. J Med Virol. 2021;93(1):194-6. https://doi.org/10.1002/jmv.26311 https://doi.org/10.1002/jmv.26311... )
Total	35	100	...

[1] Corresponding author: Beibilene Perlato Melo da Silva E-mail: beibilene@estudante.ufscar.br

Brasil

Brasil

Drug-Resistant Tuberculosis and COVID-19: A Scoping Review on a New Threat to Antimicrobial Resistance

Tuberculosis Resistente a Medicamentos y COVID-19: Una Revisión de Alcance de una Nueva Amenaza a la Resistencia Antimicrobiana

ABSTRACT

Objective:

Methods:

Results:

Conclusions: