Syphilis in pregnancy and factors associated with congenital syphilis in Belo Horizonte-MG, Brazil, 2010-2013

Solange Maria Nonato Ana Paula Souto Melo Mark Drew Crosland Guimarães About the authors


to estimate congenital syphilis (CS) incidence and associated factors in conceptae of pregnant women with syphilis attending primary health care centers in Belo Horizonte-MG, Brazil.


retrospective cohort study of the period November/2010 to September/2013; data was obtained from electronic medical records; relative risk (RR) and 95% confidence intervals (95%CI) were calculated.


353 pregnant women with syphilis were included in the study; cumulative CS incidence was 33.4%; statistically associated factors were maternal age <20 years (RR=1.44; 95%CI: 1.05;1.99), low schooling (RR=1.64; 95%CI: 1.02;2.62), late starting of prenatal care (RR=1.65; 95%CI: 1.21;2.27), having less than six prenatal checkups (RR=1.37; 95%CI: 1.02;1.84), not having nontreponemal test (Venereal Disease Research Laboratory [VDRL]) in the first quarter (RR=1.68; 95%CI: 1.21;2.32), titer of the first (RR=2.86; 95%CI: 1.85;4.41) and last VDRL test ≥1:8 (RR=2.35; 95%CI: 1.62;3.42).


congenital syphilis incidence suggests failures in prenatal care and indicates the need for new strategies to reduce vertical transmission of the disease.

Syphilis, Congenital; Pregnancy; Prenatal Care; Risk Factors; Cohort Studies

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