Síndrome de Parinaud causada por Bartonella henselae: relato de caso

rimtsp Revista do Instituto de Medicina Tropical de São Paulo Rev. Inst. Med. trop. S. Paulo 1678-9946 Instituto de Medicina Tropical São Paulo, SP, Brazil Os autores relatam um caso do Síndrome de Parinaud (conjuntivite com adenite satélite pré-auricular) causada por Bartonella henselae, o agente etiológico da Doença da Arranhadura do Gato. O esclarecimento etiológico deste caso foi feito através da reação de imunofluorescência indireta o que permitiu um adequado enfoque terapêutico e acompanhamento do paciente, evitando o uso de antibióticos inadequados e intervenções cirúrgicas. CASE REPORT Parinaud syndrome caused by Bartonella henselae: case report Síndrome de Parinaud causada por Bartonella henselae: relato de caso Carlos Alberto YamashitaI; Adriana MielleI; Natasha SlhessarenkoII; Sérgio NascimentoI; Alfredo GilioI; Márcia PahlI; Bernardo EjzenbergIII; Evandro BaldacciIII; Yassuhiko OkayIV IMD. Pediatric Division of the University Hospital, Pediatric Department of the School of Medicine of the University of São Paulo IIMD. Hospital das Clínicas of the School of Medicine of the University of São Paulo IIIPhD, MD. Pediatric Division of the University Hospital, Pediatric Department of the School of Medicine of the University of São Paulo IVPhD, MD. Chairman of Pediatrics Department. Pediatric Division of the University Hospital of the School of Medicine of the University of São Paulo Correspondence to SUMMARY The authors report a case of Parinaud syndrome (conjunctivitis with pre-auricular satellite adenitis) caused by Bartonella henselae, the etiologic agent of Cat Scratch Disease. The etiologic assessment of this case was performed by serum indirect immunofluorescence reaction and allowed for a better therapeutics and follow up, avoiding ineffective antibiotics and surgical interventions. Keywords: Cat Scratch Disease; Parinaud Syndrome; Bartonella henselae. RESUMO Os autores relatam um caso do Síndrome de Parinaud (conjuntivite com adenite satélite pré-auricular) causada por Bartonella henselae, o agente etiológico da Doença da Arranhadura do Gato. O esclarecimento etiológico deste caso foi feito através da reação de imunofluorescência indireta o que permitiu um adequado enfoque terapêutico e acompanhamento do paciente, evitando o uso de antibióticos inadequados e intervenções cirúrgicas. Full text available only in PDF format. Texto completo disponível apenas em PDF. REFERENCES 1. ADAL, K.A.; COCKERELL, C.J. & PETRI Jr., W.A. - Cat Scratch Disease, Bacillary Angiomatosis, and other infections due to Rochalimae. New Engl. J. Med., 330: 1509-1515, 1994. Correspondence to: Dr. Carlos Alberto Yamashita Pediatric Division of the University Hospital Av. Prof. Lineu Prestes 2565 Cidade Universitária, 05508-900 São Paulo, SP, Brasil Recebido para publicação em 06/09/1996 Aceito para publicação em 03/12/1996 2. APALSCH, A.M.; NOUR, B. & JAFFE, R. - Systemic Cat-Scratch Disease in a pediatric liver transplant recipient and review of the literature. Pediat. infect. Dis. J., 12: 769-773, 1993. Systemic Cat-Scratch Disease in a pediatric liver transplant recipient and review of the literature Pediat. infect. Dis. J. 1993 769 773 12 APALSCH A.M. NOUR B JAFFE R 3. BARKA, N.E.; HADFIELD, T.; PATNAIK, M. et al. - EIA for detection of Rachalimaea henselae - reactive IgG, IgM and IgA antibodies in patients with suspected Cat-Scratch Disease. J. infect. Dis., 167: 1503-1504, 1993. EIA for detection of Rachalimaea henselae - reactive IgG, IgM and IgA antibodies in patients with suspected Cat-Scratch Disease J. infect. Dis. 1993 1503 1504 167 BARKA N.E. HADFIELD T PATNAIK M 4. BERGMANS, A.M.C.; GROOTHEDDE, J.W.; SCHELLEKENS, J.F.P. et al. - Etiology of Cat Scratch Disease. Comparison of polymerase chain reaction detection of Bartonella (formerly Rochalimaea) and Afipia felis DNA with serology and skin tests. J. infect. Dis., 171: 916-923, 1995. Etiology of Cat Scratch Disease.: Comparison of polymerase chain reaction detection of Bartonella (formerly Rochalimaea) and Afipia felis DNA with serology and skin tests J. infect. Dis. 1995 916 923 171 BERGMANS A.M.C. GROOTHEDDE J.W. SCHELLEKENS J.F.P. 5. BERNINI, P.M.; GORCZYCA, J.T. & MODLIN, J.F. - Cat-Scratch Disease presenting as paravertebral abscess. J. Bone Jt. Surg., 76: 1858-1863, 1994. Cat-Scratch Disease presenting as paravertebral abscess J. Bone Jt. Surg. 1994 1858 1863 76 BERNINI P.M. GORCZYCA J.T. MODLIN J.F. 6. CARITHERS, H.A. - Cat-Scratch Disease: an overview based on a study of 1,200 patients. Amer. J. Dis. Child., 139: 1124-1133, 1985. Cat-Scratch Disease: an overview based on a study of 1,200 patients Amer. J. Dis. Child. 1985 1124 1133 139 CARITHERS H.A. 7. COHEN, S.M.; DAVIS, J.L. & GOSS, D.M. - Branch retinal arterial occlusions in multifocal retinites with optic nerce edema. Arch. Ophthal., 113: 1271-1276, 1995. Branch retinal arterial occlusions in multifocal retinites with optic nerce edema Arch. Ophthal. 1995 1271 1276 113 COHEN S.M. DAVIS J.L. GOSS D.M. 8. DALTON, M.J.; ROBINSON, L.E.; COOPER, J. et al. - Use of Bartonella antigens for serologic diagnosis of Cat-Scratch Disease at a national referral center. Arch. intern. Med., 155: 1670-1676, 1995. Use of Bartonella antigens for serologic diagnosis of Cat-Scratch Disease at a national referral center Arch. intern. Med. 1995 1670 1676 155 DALTON M.J. ROBINSON L.E. COOPER J 9. DANGMAN, B.C.; ALBANESE, B.A.; KACILA, M.A. et al. - Cat Scratch Disease in two children presenting with fever of unknown origin imaging features and association with a new causative agent, Rochalimaea henselae. Pediatrics, 95: 767-771, 1995. Cat Scratch Disease in two children presenting with fever of unknown origin imaging features and association with a new causative agent, Rochalimaea henselae Pediatrics 1995 767 771 95 DANGMAN B.C. ALBANESE B.A. KACILA M.A. 10. FUMAROLA, D.; GIULIANI, G. & PECE, S. - Pathogenic mechanisms of Bartonella henselae infections. Pediat. infect. Dis. J., 15: 385-386, 1996. Pathogenic mechanisms of Bartonella henselae infections Pediat. infect. Dis. J. 1996 385 386 15 FUMAROLA D GIULIANI G PECE S 11. GOLDEN, S.E. - Hepatoesplenic Cat-Scratch Disease associated with elevated anti-Rochalimaea antibody titers. Pediat. infect. Dis. J., 12: 868-870, 1993. Hepatoesplenic Cat-Scratch Disease associated with elevated anti-Rochalimaea antibody titers Pediat. infect. Dis. J. 1993 868 870 12 GOLDEN S.E. 12. GORAL, S.; ANDERSON, B.; HAGER, C. et al. - Detection of Rochalimaea henselae DNA by polymerase chain reaction from suppurative nodes of children with Cat-Scratch Disease. Pediat. infect. Dis. J., 13: 994-997, 1994. Detection of Rochalimaea henselae DNA by polymerase chain reaction from suppurative nodes of children with Cat-Scratch Disease Pediat. infect. Dis. J. 1994 994 997 13 GORAL S ANDERSON B HAGER C 13. HADLEY, S.; ALBRECHT, M.A. & TARSY, D. - Cat-Scratch encephalopathy: a cause of status epilepticus and coma in a healthy young adult. Neurology, 45: 196, 1995. Cat-Scratch encephalopathy: a cause of status epilepticus and coma in a healthy young adult Neurology 1995 196 45 HADLEY S ALBRECHT M.A. TARSY D 14. HAMILTON, D.H.; ZANGWILL; K.M.; HADLER, J.L. & CARTTER, M.L. - Cat-Scratch Disease - Connecticut, 1992-1993. J. infect. Dis., 172: 570-573, 1995. Cat-Scratch Disease - Connecticut: 1992-1993 J. infect. Dis. 1995 570 573 172 HAMILTON D.H. ZANGWILL K.M. HADLER J.L. CARTTER M.L. 15. KOHLER, J.E.; GLASER, G.A. & TAPPERO, J.W. - Rochalimaea henselae infection: a new zoonosis of domestic cat as a reservoir. J. Amer. med. Ass., 271: 531-535, 1994. Rochalimaea henselae infection: a new zoonosis of domestic cat as a reservoir J. Amer. med. Ass. 1994 531 535 271 KOHLER J.E. GLASER G.A. TAPPERO J.W. 16. MARGILETH, A.M. - Antibiotic therapy for Cat-Scratch Disease: clinical study of therapeutic outcome in 268 patients and a review of the literature. Pediat. infec. Dis. J., 11: 474-478, 1992. Antibiotic therapy for Cat-Scratch Disease: clinical study of therapeutic outcome in 268 patients and a review of the literature Pediat. infec. Dis. J. 1992 474 478 11 MARGILETH A.M. 17. MARGILETH, A.M. - Cat Scratch Disease. In: BEHRMAN, R.E.; KLIEGMAN, R.M. & ARVIN, A.M., ed. Nelson textbook of pediatrics. Philadelphia. Saunders, 1996. p. 865-867. Nelson textbook of pediatrics 1996 865 867 MARGILETH A.M. BEHRMAN R.E. KLIEGMAN R.M. ARVIN A.M. 18. NOAH, D.L.; BRESEE, J.S.; GORENSEK. M.J. et al. - Cluster of five children with acute encephalopathy associated with Cat-Scratch Disease in South Florida. Pediat. infect. Dis. J., 14: 866-869, 1995. Cluster of five children with acute encephalopathy associated with Cat-Scratch Disease in South Florida Pediat. infect. Dis. J. 1995 866 869 14 NOAH D.L. BRESEE J.S. GORENSEK M.J. 19. RO, J.Y.; BATSAKIS, J.G. & FRAUENHOFFER, E.E. - Bacillary angiomatosis. Ann. Otol. (St Louis), 104: 668-672, 1995. Bacillary angiomatosis Ann. Otol. 1995 668 672 104 RO J.Y. BATSAKIS J.G. FRAUENHOFFER E.E. 20. SZELC-KELLY, C.; GORAL, S.; PEREZ-PEREZ, G.I. et al. - Serologic responses to Bartonella and Afípia antigens in patients with Cat Scratch Disease. Pediatrics, 96: 1137-1142, 1995. Serologic responses to Bartonella and Afípia antigens in patients with Cat Scratch Disease Pediatrics 1995 1137 1142 96 SZELC-KELLY C GORAL S PEREZ-PEREZ G.I. 21. WALDVOGEL, K.; REGNERY, R.L.; ANDERSON, B.E. et al. - Disseminated Cat-Scratch Disease: detection of Rochalimaea henselae in affected tissue. Europ. J. Pediat., 153: 23-27, 1994. Disseminated Cat-Scratch Disease: detection of Rochalimaea henselae in affected tissue Europ. J. Pediat. 1994 23 27 153 WALDVOGEL K. REGNERY R.L. ANDERSON B.E. 22. WHITMAN, B.W. & KRAFTE-JACOBS, B. - Cat-Scratch Disease associated with pleural effusions and encephalopathy in a child. Respiration, 62: 171-173, 1995. Cat-Scratch Disease associated with pleural effusions and encephalopathy in a child Respiration 1995 171 173 62 WHITMAN B.W. KRAFTE-JACOBS B