Aplastic crisis due to human parvovirus B19 infection in hereditary hemolytic anaemia

Crise aplástica devido à infecção por parvovirus humano B19 em anemia hemolítica hereditária

Specific anti-B19 IgM was demonstrated in sera from three children showing transient aplastic crisis. A two years-old boy living in Rio de Janeiro suffering from sickle-cell anaemia showed the crisis during August, 1990. Two siblings living in Santa Maria, RS, developed aplastic crisis during May, 1991, when they were also diagnosed for hereditary spherocytosis. For a third child from this same family, who first developed aplastic crisis no IgM anti-B19 was detected in her sera.

Human parvovirus B19; Transient aplastic crisis; Hereditary spherocytosis; Sickle-cell disease

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