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Revista do Instituto de Medicina Tropical de São Paulo

On-line version ISSN 1678-9946

Rev. Inst. Med. trop. S. Paulo vol.28 no.4 São Paulo July/Aug. 1986 


Estudios inmunologicos en hamsters (Cricetus auratus) infectados con Schistosoma mansoni(1)


Immunologic studies in hamsters (Cricetus auratus) infected with Schistosoma mansoni



Eduardo MongeI; Paulo M. Z. CoelhoII; Carlos A. P. TavaresIII

IDepartamento de Parasitologia, Universidad de Costa Rica, San José, Costa Rica
IIDepartamento de Parasitologia, Instituto de Ciências Biológicas, UFMG, Belo Horizonte, Brasil
IIIDepartamento de Bioquímica-Imunologia, Instituto de Ciências Biológicas, UFMG, Belo Horizonte, Brasil




Los resultados de este trabajo muestran que el hamster (Cricetus auratus) puede ser utilizado como un modelo experimental para estudios inmunológicos en la infección por Schistosoma mansoni. Los datos obtenidos, relativos a inmunidad concomitante, producción de anticuerpo letal e inmunosupresión se asemejan a los conseguidos en otros modelos experimentales ya establecidos. Estas observaciones indican que el hámster, además de ser un hospedero satisfactorio para el mantenimiento del parásito en el laboratorio, puede ser considerado como un modelo experimental alterno cuyo crecimiento y mantenimiento son relativamente simples y además es un animal de fácil manejo.

Unitermos: Esquistosomíase mansonica experimental — Hámster (Cricetus auratus) — Inmunologia


The results of this investigation show that the hamsters (Cricetus auratus) may be used as an experimental model for immunological studies in Schistosoma mansoni. The data obtained referring to concomitant immunity, production of lethal antibodies and immunosuppression, resemble data from other established experimental models.
Our observations indicate that the hamster has the following advantages: 1. It is an appropriate host for the maintenance of S. mansoni in the laboratory. 2. It can be considered an alternative model for easy growth and maintenance of this parasite. 3. It is easy to handle.



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Recebido para publicação em 27/8/1985.



(1) Este trabajo fue financiado, en parte, por el "Conselho Nacional de Desenvolvimento Científico e Tecnológico do Brasil" e FINEP (Financiadora de Estudos e Projetos).

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