Tomographic imaging of fragmented cortical bone heteroimplant and methylmethacrylate in segmental bone defect of rabbit tibia¹

PURPOSE:

To evaluate the performance of composites consisting of fragmented cortical bone heteroimplant in association with methylmethacrylate preserved in 98% glycerin, in segmental bone defect of rabbit tibia medial metaphysis.

METHODS:

In this study were used twelve adult New Zealand rabbits, divided into three groups of four animals each: G30 (30 days), G60 (60 days) and G90 (90 days). The bone defects previously created in the tibia were filled with composites and both were evaluated by cone-beam computed tomography, immediately after surgery and after 30, 60, and 90 days.

RESULTS:

The composites fulfilled and remained in the sites of bone defects in all cases and were not registered signals of infection, migration or rejection.

CONCLUSIONS:

The implanted composites promoted the bone defects repair without signals of infection and/or rejection. The composites are one more option for bone defects repair.

Biocompatible Materials; Tomography; Tibia; Rabbits