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Bilateral occipital calcification, epilepsy and coeliac disease: case report

Carlos Henrique Souza Santos Iara Leda Brandão de Almeida Maria Durce Costa Gomes Alexandre Serafim Mariana Machado Pereira Mauro Muszkat Sueli Rizzutti Francy Reis da Silva Patrício Mônica Carolina Miranda Luiz Celso Pereira Vilanova About the authors

We report a case of a six-year-old girl with frequent diarrhea episodes associated with ferroprive anemia from 6 months of age, normal neuromotor development and partial seizures initiated in her 3rd year which was controlled with carbamazepine. CT scan in her 5th year of age demonstrated gyral calcifications in the occipital and posterior parietal regions bilaterally. MRI has shown low signal areas in the axial T2 sequences corresponding to the gyral calcifications evident on the CT. Blood investigation for coeliac disease with antigliadin, endomysial and transglutaminase antibodies was positive and the intestinal biopsy has showed villous atrophy associated with an increased number of intraepithelial lymphocytes and hypertrophic criptae compatible with coeliac disease.

coeliac disease; epilepsy; intracranial calcification


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