Brummel et al. (2014)
Brummel, N. E., Girard, T. D., Ely, E. W., Pandharipande, P. P., Morandi, A., Hughes, C. G., Graves, A. J., Shintani, A., Murphy, E., Work, B., Pun, B. T., Boehm, L., Gill, T. M., Dittus, R. S., & Jackson, J. C. (2014). Feasibility and safety of early combined cognitive and physical therapy for critically ill medical and surgical patients: the Activity and Cognitive Therapy in ICU (ACT-ICU) trial. Randomized Controlled Trial, 40(3), 370-379. http://dx.doi.org/10.1007/s00134-013-3136-0. http://dx.doi.org/10.1007/s00134-013-313...
|
Early and combined use of cognitive therapy. |
Randomized. |
(1) Yes. |
Viable and safe, even under mechanical ventilation. |
7/10 |
(2) Cognitive Therapy (Problem-solving; multi-step task execution). |
Corcoran et al. (2017)
Corcoran, J. R., Herbsman, J. M., Bushnik, T., Van Lew, S., Stolfi, A., Parkin, K., McKenzie, A., Hall, G. W., Joseph, W., Whiteson, J., & Flanagan, S. R. (2017). Early rehabilitation in the medical and surgical intensive care units for patients with and without mechanical ventilation: an interprofessional performance improvement project. PM & R, 9(2), 113-119. http://dx.doi.org/10.1016/j.pmrj.2016.06.015. http://dx.doi.org/10.1016/j.pmrj.2016.06...
|
Early mobilization in the ICU. |
Prospective. |
(1) No. |
Viable with reduced hospitalization and ICU stay. |
5/10 |
(2) Exercises in bed; Standing up; Ambulation. |
Davis et al. (2013)
Davis, J., Crawford, K., Wierman, H., Osgood, W., Cavanaugh, J., Smith, K. A., Mette, S., & Orff, S. (2013). Mobilization of ventilated older adults. Journal of Geriatric Physical Therapy, 36(4), 162-168. http://dx.doi.org/10.1519/JPT.0b013e31828836e7. http://dx.doi.org/10.1519/JPT.0b013e3182...
|
Feasibility of early mobilization in the ICU and functionality under mechanical ventilation. |
Cohort. |
(1) No. |
Viable, safe, and well-tolerated under mechanical ventilation. |
5/10 |
(2) Decubitus change, sitting on the bed and the edge of the bed; Standing up; Sitting on the chair; Walking. |
Deluzio et al. (2018)
Deluzio, S., Vora, I., Kumble, S., Zink, E. K., Stevens, R. D., & Bahouth, M. N. (2018). Feasibility of early, motor-assisted cycle ergometry in critically Ill neurological patients with upper limb weakness and variable cognitive status: a case series. American Journal of Physical Medicine & Rehabilitation, 97(5), e37-e41. http://dx.doi.org/10.1097/PHM.0000000000000857. http://dx.doi.org/10.1097/PHM.0000000000...
|
Viability of the Cycloergometer in critical neurological patients. |
Cohort. |
(1) Yes. |
Viable, safe and does not bring physiological, neurological, or cognitive changes. |
4/10 |
(2) Missing description. |
Fields et al. (2015)
Fields, C., Trotsky, A., Fernandez, N., & Smith, B. A. (2015). Mobility and ambulation for patients with pulmonary artery catheters: a retrospective descriptive study. Journal of Acute Care Physical Therapy, 6(2), 64-70. http://dx.doi.org/10.1097/JAT.0000000000000012. http://dx.doi.org/10.1097/JAT.0000000000...
|
Early mobilization and associated adverse events. |
Retrospective. |
(1) Yes. |
Safe and effective. |
4/10 |
(2) Missing description. |
Hsu et al. (2020)
Hsu, S. H., Campbell, C., Weeks, A. K., Herklotz, M., Kostelecky, N., Pastores, S. M., Halpern, N. A., & Voigt, L. P. (2020). A pilot survey of ventilated cancer patients’ perspectives and recollections of early mobility in the intensive care unit. Supportive Care in Cancer, 28(2), 747-753. http://dx.doi.org/10.1007/s00520-019-04867-1. http://dx.doi.org/10.1007/s00520-019-048...
|
Level of recall, satisfaction, and benefits during mechanical ventilation. |
Pilot Study. |
(1) Yes. |
Compromise of factual memory. |
5/10 |
(2) Postural control; Equilibrium reaction; ROM; Sitting and standing up; Transferring to a chair and the bed; Ambulation. |
Jolley et al. (2015)
Jolley, S. E., Dale, C. R., & Hough, C. L. (2015). Hospital-level factors associated with report of physical activity in patients on mechanical ventilation across Washington State. Annals of the American Thoracic Society, 12(2), 209-215. http://dx.doi.org/10.1513/AnnalsATS.201410-480OC. http://dx.doi.org/10.1513/AnnalsATS.2014...
|
Early mobilization, mechanical ventilation, and associated care. |
Transversal. |
(1) No. |
Wide use of early mobilization in the ICU: 95.7% without mechanical ventilation; and 76.6%, under mechanical ventilation. |
5/10 |
(2) Weight transfer in the bed; Standing up; Walking; Transferring from bed to chair; and Ambulation. |
Jolley et al. (2017)
Jolley, S. E., Moss, M., Needham, D. M., Caldwell, E., Morris, P. E., Miller, R. R., Ringwood, N., Anders, M., Koo, K. K., Gundel, S. E., Parry, S. M., & Hough, C. L., & Acute Respiratory Distress Syndrome Network Investigators. (2017). Point Prevalence study of mobilization practices for acute respiratory failure patients in the United States. Critical Care Medicine, 45(2), 205-215. http://dx.doi.org/10.1097/CCM.0000000000002058. http://dx.doi.org/10.1097/CCM.0000000000...
|
Prevalence of mobilization in ICUs and progression of mobility. |
Cohort. |
(1) No. |
Prevalence: 32% of patients in the ICU; 16% under mechanical ventilation; and 4% out of bed. |
5/10 |
(2) ROM, passive; Sitting on the bed; Sitting on the edge of the bed; Standing up; Transferring of the chair to the standing position; Walking at the same point; Ambulation. |
Needham et al. (2010)
Needham, D. M., Korupolu, R., Zanni, J. M., Pradhan, P., Colantuoni, E., Palmer, J. B., Brower, R. G., & Fan, E. (2010). Early physical medicine and rehabilitation for patients with acute respiratory failure: a quality improvement project. Archives of Physical Medicine and Rehabilitation, 91(4), 536-542. http://dx.doi.org/10.1016/j.apmr.2010.01.002. http://dx.doi.org/10.1016/j.apmr.2010.01...
|
Practices of sedation and analgesia in the ICU and functional mobilization. |
Retrospective. |
(1) No. |
Deep sedation was not necessary and there was tolerance to mechanical ventilation. Viable, safe, and reduced hospitalization. |
5/10 |
(2) Sitting on the bed; Sitting on the edge of the bed; Transferring from bed to chair; Transferring from sitting to standing; and Ambulation. |
Pohlman et al. (2010)
Pohlman, M. C., Schweickert, W. D., Pohlman, A. S., Nigos, C., Pawlik, A. J., Esbrook, C. L., Spears, L., Miller, M., Franczyk, M., Deprizio, D., Schmidt, G. A., Bowman, A., Barr, R., McCallister, K., Hall, J. B., & Kress, J. P. (2010). Feasibility of physical and occupational therapy beginning from initiation of mechanical ventilation. Critical Care Medicine, 38(11), 2089-2094. http://dx.doi.org/10.1097/CCM.0b013e3181f270c3. http://dx.doi.org/10.1097/CCM.0b013e3181...
|
Daily interruption of sedation and early mobilization. |
Retrospective. |
(1) No. |
Viable and safe right after intubation (ICU). |
5/10 |
(2) ROM (passive, assisted or active); Bed mobility; Sitting down; Standing up; Ambulation; Balance. |
Schweickert et al. (2009)
Schweickert, W. D., Pohlman, M. C., Pohlman, A. S., Nigos, C., Pawlik, A. J., Esbrook, C. L., Spears, L., Miller, M., Franczyk, M., Deprizio, D., Schmidt, G. A., Bowman, A., Barr, R., McCallister, K. E., Hall, J. B., & Kress, J. P. (2009). Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial. Lancet, 373(9678), 1874-1882. http://dx.doi.org/10.1016/S0140-6736(09)60658-9. http://dx.doi.org/10.1016/S0140-6736(09)...
|
Early mobilization, interruption of sedation, and functional and psychiatric results. |
Randomized. |
(1) No. |
Safe, well-tolerated, improving functional status, reducing symptoms associated with the ICU, and increasing weaning. |
8/10 |
(2) Movements (liabilities, assisted and active); Bed mobility (weight transfer, sitting on the bed); Balance; Standing, Sitting in a chair; Ambulation. |
Sigler et al. (2016)
Sigler, M., Nugent, K., Alalawi, R., Selvan, K., Tseng, J., Edriss, H., Turner, A., Valdez, K., & Krause, D. (2016). Making of a successful early mobilization program for a medical intensive care unit. Southern Medical Journal, 109(6), 342-345. http://dx.doi.org/10.14423/SMJ.0000000000000472. http://dx.doi.org/10.14423/SMJ.000000000...
|
Implementation of an early mobilization program. |
Cohort. |
(1) No. |
Simple, progressive mobilization, with modification of the analgesic and sedation regimen. |
5/10 |
(2) Weight transfer in the bed; Sitting on the bed; ROM (passive, assisted, or active); Sitting on the edge of the bed; Standing up, turning, and sitting on a chair; Standing a few steps and sitting on a chair; Ambulation. |
Titsworth et al. (2012)
Titsworth, W. L., Hester, J., Correia, T., Reed, R., Guin, P., Archibald, L., Layon, A. J., & Mocco, J. (2012). The effect of increased mobility on morbidity in the neurointensive care unit. Journal of Neurosurgery, 116(6), 1379-1388. http://dx.doi.org/10.3171/2012.2.JNS111881. http://dx.doi.org/10.3171/2012.2.JNS1118...
|
Early mobilization in the neuro-intensive care unit. |
Retrospective. |
(1) No. |
It does not harm the patient's critical condition and reduces the ICU stay. |
5/10 |
(2) Sitting on the bed; Sitting on the edge of the bed; Getting out of bed; Walking to the bathroom; Exiting the room; Exercising. |
Wahab et al. (2016)
Wahab, R., Yip, N. H., Chandra, S., Nguyen, M., Pavlovich, K. H., Benson, T., Vilotijevic, D., Rodier, D. M., Patel, K. R., Rychcik, P., Perez-Mir, E., Boyle, S. M., Berlin, D., Needham, D. M., & Brodie, D. (2016). The implementation of an early rehabilitation program is associated with reduced length of stay: A multi-ICU study. The Journal of the Intensive Care Society, 17(1), 2-11. http://dx.doi.org/10.1177/1751143715605118. http://dx.doi.org/10.1177/17511437156051...
|
Early mobilization in the ICU of a long-term hospital. |
Retrospective. |
(1) Yes. |
Reduction in ICU stay and hospitalization. |
5/10 |
(2) Missing description. |
Witcher et al. (2015)
Witcher, R., Stoerger, L., Dzierba, A. L., Silverstein, A., Rosengart, A., Brodie, D., & Berger, K. (2015). Effect of early mobilization on sedation practices in the neurosciences intensive care unit: a preimplementation and postimplementation evaluation. Journal of Critical Care, 30(2), 344-347. http://dx.doi.org/10.1016/j.jcrc.2014.12.003. http://dx.doi.org/10.1016/j.jcrc.2014.12...
|
Early mobilization and sedation in neurological patients in the ICU. |
Retrospective. |
(1) No. |
Reduced sedation, increased analgesia. It did not reduce the duration of mechanical ventilation or the length of hospital stay. |
5/10 |
(2) ROM (passive and active); Sitting down; Standing up; Walking. |
Yataco et al. (2019)
Yataco, R. A., Arnold, S. M., Brown, S. M., David Freeman, W., Carmen Cononie, C., Heckman, M. G., Partridge, L. W., Stucky, C. M., Mellon, L. N., Birst, J. L., Daron, K. L., Zapata-Cooper, M. H., & Schudlich, D. M. (2019). Early progressive mobilization of patients with external ventricular drains: safety and feasibility. Neurocritical Care, 30(2), 414-420. http://dx.doi.org/10.1007/s12028-018-0632-7. http://dx.doi.org/10.1007/s12028-018-063...
|
Adverse mobilization events. |
Retrospective. |
(1) No. |
Safety, feasible with low rates of adverse events. |
5/10 |
(2) Transferring (from lying to sitting); Sitting on the edge of the bed; Standing up; Sitting on a chair; Ambulation. |
Zanni et al. (2010)
Zanni, J. M., Korupolu, R., Fan, E., Pradhan, P., Janjua, K., Palmer, J. B., Brower, R. G., & Needham, D. M. (2010). Rehabilitation therapy and outcomes in acute respiratory failure: an observational pilot project. Journal of Critical Care, 25(2), 254-262. http://dx.doi.org/10.1016/j.jcrc.2009.10.010. http://dx.doi.org/10.1016/j.jcrc.2009.10...
|
Physiological effects and safety of rehabilitation in the ICU. |
Cohort. |
(1) No. |
Safe, without significant physiological changes or adverse effects. |
5/10 |
(2) ROM; Muscle strength; Occupation; Bed positioning; Sitting on the bed; Sitting on the edge of the bed; Transferring from seated to standing; Ambulation; Activities. |