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Blood urea nitrogen and creatinine levels in dogs with acute leptospirosis determined by Icterohaemorrhagiae serogroup

One hundred and twenty serum samples from dogs with specific titres (<FONT FACE=Symbol>³</FONT>100) against Leptospira sp. serovar Icterohaemorrhagiae for the dosage of blood urea nitrogen (BUN) and creatinine levels were tested. Animals presenting titres <FONT FACE=Symbol>³</FONT>800 showed BUN levels higher than reference values while samples with titres <FONT FACE=Symbol>³</FONT>200 and <FONT FACE=Symbol>£</FONT>400 presented BUN levels significantly lower (P<0.05) than the others, but still higher than the reference values. Samples presenting titres lower than 200 showed BUN dosages according to the reference values. In relation to creatinine dosage, only samples presenting titres <FONT FACE=Symbol>³</FONT>800 showed dosages higher than the reference values. A correlation between renal damage and specific seroreactivity for leptospirosis was demonstrated.

Leptospirosis; dogs; BUN; creatinine; Icterohaemorrhagiae

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