Mortality related to tuberculosis-HIV/AIDS co-infection in Brazil, 2000-2011: epidemiological patterns and time trends

Mortalidade relacionada à coinfecção tuberculose e HIV/AIDS no Brasil, 2000-2011: padrões epidemiológicos e tendências temporais

Mortalidad relacionada con la coinfección de tuberculosis y VIH/SIDA en Brasil, 2000-2011: patrones epidemiológicos y tendencias temporales

Mauricélia da Silveira Lima Francisco Rogerlândio Martins-Melo Jorg Heukelbach Carlos Henrique Alencar Reagan Nzundu Boigny Alberto Novaes Ramos JúniorAbout the authors


Co-infection of tuberculosis (TB)-HIV/AIDS is a persistent public health problem in Brazil. This study describes epidemiological patterns and time trends of mortality related to TB-HIV/AIDS co-infection. Based on mortality data from 2000-2011 (almost 12.5 million deaths), 19,815 deaths related to co-infection were analyzed. The average age-adjusted mortality rate was 0.97 deaths/100,000 inhabitants. The highest mortality rates were found among males, those in economically productive age groups, black race/color and residents of the South region. There was a significant reduction in the mortality coefficient at the national level (annual average percent change: -1.7%; 95%CI: -2.4; -1.0), with different patterns among regions: increases in the North, Northeast and Central regions, a reduction in the Southeast and a stabilization in the South. The strategic integration of TB-HIV/AIDS control programmes is fundamental to reduce the burden of mortality related to co-infection in Brazil.

Tuberculosis; HIV; Acquired Immunodeficiency Syndrome; Time Series Studies

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