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L-methylfolate, a new option in psychiatric treatment, would it be linked to psoriasis relapse?

Rubens Pitliuk Tatyanny Paula Pinto da Costa Santos Fucci About the authors


We report a case of a 61-years-old woman in remission of psoriasis for 20 years. She presented recurrence of psoriasis in the form of plaques few days after taking L-methylfolate 15mg/day. The L-methylfolate was prescribed as an adjuvant for the treatment of depression in a patient with the methylenetetrahydrofolate reductase gene polymorphism (MTHFR).

Psoriasis; Methylenetetrahydrofolatereductase (NADPH2); Polymorphism, genetic; Depression; L-5-methyltetrahydrofolate; L-Methylfolate

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