This special volume of Memorias do Instituto Oswaldo Cruz is entirely dedicated to the Proceedings of the International Symposium Nitric Oxide, Cytokines and Inflammation, held in Rio de Janeiro, Brazil, from June 6 to 9, 2004 under the coordination of Nobel Laureate Louis J Ignarro (US), John L Wallace (CA) and Renato SB Cordeiro (BR). The meeting was supported by the Oswaldo Cruz Foundation, University of Calgary, University of California Los Angeles, the Brazilian Society of Pharmacology and Experimental Therapeutics, the Canadian Association of Gastroenterology and a great number of Brazilian research financing agencies, pharmaceutical companies, Brazilian official banks and companies. The conference gathered 480 participants including 35 invited speakers working at the frontier of this field, researchers, clinicians, representatives from industry, post-doctoral fellows and students. Two hundred and ninety posters were presented by international scientists, including many young Brazilian, British, Canadian and Hungarian researchers. The 15 best posters were selected by an international scientific committee and awarded prizes at the end of the meeting.

This conference was devoted to novel aspects of basic science and pharmacology of inflammation, therapeutic potential of new compounds, including the mechanism of action of glucocorticoids and the anti-inflammatory properties of NO-aspirin type compounds, modulation of allergic inflammation, chemotactic factors, NO as a modulator of proliferation and mechanisms of pain sensation and treatment of pulmonary inflammation, mechanisms, and mediators of allergic inflammation, NO and NO donors as pro- or anti-inflammatory agents, mediators that regulate the resolution of inflammation, microbial-epithelial interactions as they pertain to inflammation, protease-activated-receptors pain, and inflammatory signaling.

We believe that the 37 papers and reviews published in these Proceedings give an overview of the richness and diversity of presentations and discussions that occurred at this Brazilian meeting, reflect the state-of-the-art of investigations involving NO, Cytokines and Inflammation around the world, and will be able to contribute significantly to the advance of knowledge in this field.

The Editors

Publication Dates

  • Publication in this collection
    14 June 2005
  • Date of issue
    Mar 2005
Instituto Oswaldo Cruz, Ministério da Saúde Av. Brasil, 4365 - Pavilhão Mourisco, Manguinhos, 21040-900 Rio de Janeiro RJ Brazil, Tel.: (55 21) 2562-1222, Fax: (55 21) 2562 1220 - Rio de Janeiro - RJ - Brazil